(Q44895447)

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Distinct patterns of novel gene mutations in poor-prognostic stereotyped subsets of chronic lymphocytic leukemia: the case of SF3B1 and subset #2.

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Europe PubMed Central

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7 December 2017

Distinct patterns of novel gene mutations in poor-prognostic stereotyped subsets of chronic lymphocytic leukemia: the case of SF3B1 and subset #2. (English)

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7 December 2017

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chronic lymphocytic leukemia

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based on heuristic

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24

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K Plevova

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author name string

J C Strefford

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L-A Sutton

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P Baliakas

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A Agathangelidis

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J Malčíková

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L Scarfó

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Z Davis

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E Stalika

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D Cortese

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N Cahill

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L B Pedersen

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P F di Celle

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T Tzenou

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C Geisler

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P Panagiotidis

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A W Langerak

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N Chiorazzi

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S Pospisilova

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D Oscier

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F Davi

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C Belessi

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L Mansouri

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K Stamatopoulos

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R Rosenquist

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publication date

5 April 2013

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2196-2199

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7 December 2017

https://scigraph.springernature.com/pub.10.1038/leu.2013.98

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Chronic lymphocytic leukemia B cells express restricted sets of mutated and unmutated antigen receptors.

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2013.98

21 January 2018

Chronic lymphocytic leukemias utilizing the VH3-21 gene display highly restricted Vlambda2-14 gene use and homologous CDR3s: implicating recognition of a common antigen epitope.

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2013.98

21 January 2018

Multiple distinct sets of stereotyped antigen receptors indicate a role for antigen in promoting chronic lymphocytic leukemia

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https://api.crossref.org/works/10.1038%2FLEU.2013.98

21 January 2018

Subsets with restricted immunoglobulin gene rearrangement features indicate a role for antigen selection in the development of chronic lymphocytic leukemia

1 reference

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21 January 2018

Over 20% of patients with chronic lymphocytic leukemia carry stereotyped receptors: Pathogenetic implications and clinical correlations.

1 reference

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21 January 2018

Stereotyped patterns of somatic hypermutation in subsets of patients with chronic lymphocytic leukemia: implications for the role of antigen selection in leukemogenesis.

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21 January 2018

Stereotyped B-cell receptors in one-third of chronic lymphocytic leukemia: a molecular classification with implications for targeted therapies

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21 January 2018

Cellular origin(s) of chronic lymphocytic leukemia: cautionary notes and additional considerations and possibilities

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Antigens in chronic lymphocytic leukemia--implications for cell origin and leukemogenesis

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21 January 2018

Strikingly homologous immunoglobulin gene rearrangements and poor outcome in VH3-21-using chronic lymphocytic leukemia patients independent of geographic origin and mutational status

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2013.98

21 January 2018

Remarkably similar antigen receptors among a subset of patients with chronic lymphocytic leukemia

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2013.98

21 January 2018

Distinctive gene expression pattern in VH3-21 utilizing B-cell chronic lymphocytic leukemia.

1 reference

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21 January 2018

High-density screening reveals a different spectrum of genomic aberrations in chronic lymphocytic leukemia patients with 'stereotyped' IGHV3-21 and IGHV4-34 B-cell receptors

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2013.98

21 January 2018

Distinct gene expression profiles in subsets of chronic lymphocytic leukemia expressing stereotyped IGHV4-34 B-cell receptors

1 reference

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21 January 2018

Toll-like receptor signaling pathway in chronic lymphocytic leukemia: distinct gene expression profiles of potential pathogenic significance in specific subsets of patients

1 reference

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21 January 2018

Distinct transcriptional control in major immunogenetic subsets of chronic lymphocytic leukemia exhibiting subset-biased global DNA methylation profiles

1 reference

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21 January 2018

Distinct innate immunity pathways to activation and tolerance in subgroups of chronic lymphocytic leukemia with distinct immunoglobulin receptors

1 reference

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21 January 2018

Whole-genome sequencing identifies recurrent mutations in chronic lymphocytic leukaemia

1 reference

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21 January 2018

Analysis of the chronic lymphocytic leukemia coding genome: role of NOTCH1 mutational activation

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2013.98

21 January 2018

SF3B1 and other novel cancer genes in chronic lymphocytic leukemia

1 reference

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Exome sequencing identifies recurrent mutations of the splicing factor SF3B1 gene in chronic lymphocytic leukemia

1 reference

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21 January 2018

Disruption of BIRC3 associates with fludarabine chemorefractoriness in TP53 wild-type chronic lymphocytic leukemia.

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2013.98

21 January 2018

Mutations of NOTCH1 are an independent predictor of survival in chronic lymphocytic leukemia

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2013.98

21 January 2018

NOTCH1 and SF3B1 mutations can be added to the hierarchical prognostic classification in chronic lymphocytic leukemia

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2013.98

21 January 2018

NOTCH1 mutations in +12 chronic lymphocytic leukemia (CLL) confer an unfavorable prognosis, induce a distinctive transcriptional profiling and refine the intermediate prognosis of +12 CLL

1 reference

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21 January 2018

The clinical significance of NOTCH1 and SF3B1 mutations in the UK LRF CLL4 trial.

1 reference

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21 January 2018

Assessment of fludarabine plus cyclophosphamide for patients with chronic lymphocytic leukaemia (the LRF CLL4 Trial): a randomised controlled trial

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21 January 2018

Guidelines for the diagnosis and treatment of chronic lymphocytic leukemia: a report from the International Workshop on Chronic Lymphocytic Leukemia updating the National Cancer Institute-Working Group 1996 guidelines

1 reference

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21 January 2018

Molecular and clinical features of chronic lymphocytic leukaemia with stereotyped B cell receptors: results from an Italian multicentre study

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https://api.crossref.org/works/10.1038%2FLEU.2013.98

21 January 2018

A different ontogenesis for chronic lymphocytic leukemia cases carrying stereotyped antigen receptors: molecular and computational evidence

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21 January 2018

Geographic patterns and pathogenetic implications of IGHV gene usage in chronic lymphocytic leukemia: the lesson of the IGHV3-21 gene

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21 January 2018

Stereotyped B-Cell Receptor Is an Independent Risk Factor of Chronic Lymphocytic Leukemia Transformation to Richter Syndrome

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21 January 2018

Recurrent cytogenetic findings in subsets of patients with chronic lymphocytic leukemia expressing IgG-switched stereotyped immunoglobulins

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The most frequent t(14;19)(q32;q13)-positive B-cell malignancy corresponds to an aggressive subgroup of atypical chronic lymphocytic leukemia

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21 January 2018

A comprehensive genetic and histopathologic analysis identifies two subgroups of B-cell malignancies carrying a t(14;19)(q32;q13) or variant BCL3-translocation

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

SF3B1, a splicing factor is frequently mutated in refractory anemia with ring sideroblasts

1 reference

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SF3B1 mutations in primary myelofibrosis: clinical, histopathology and genetic correlates among 155 patients

1 reference

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SF3B1 mutations in myelodysplastic syndromes: clinical associations and prognostic implications

1 reference

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NOTCH1 mutations identify a genetic subgroup of chronic lymphocytic leukemia patients with high risk of transformation and poor outcome.

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

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10.1038/LEU.2013.98

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Europe PubMed Central

PubMed publication ID

7 December 2017

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1 reference

Europe PubMed Central

PubMed publication ID

7 December 2017

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