(Q44897916)

7 December 2017

title

Identification of intermediates in the bile acid synthetic pathway as ligands for the farnesoid X receptor (English)

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7 December 2017

author name string

Tomoko Nishimaki-Mogami

1

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7 December 2017

Mizuho Une

2

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7 December 2017

Tomofumi Fujino

3

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7 December 2017

Yoji Sato

4

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7 December 2017

Norimasa Tamehiro

5

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7 December 2017

Yosuke Kawahara

6

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7 December 2017

Koichi Shudo

7

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7 December 2017

Kazuhide Inoue

8

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7 December 2017

language of work or name

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16 May 2004

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Journal of Lipid Research

7 December 2017

published in

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7 December 2017

volume

45

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7 December 2017

issue

8

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7 December 2017

page(s)

1538-1545

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7 December 2017

cites work

Bile acid biosynthesis

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400102-JLR200

Effects of different bile salts on steady-state mRNA levels and transcriptional activity of cholesterol 7 alpha-hydroxylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400102-JLR200

A regulatory cascade of the nuclear receptors FXR, SHP-1, and LRH-1 represses bile acid biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400102-JLR200

Molecular basis for feedback regulation of bile acid synthesis by nuclear receptors

21 January 2018

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https://api.crossref.org/works/10.1194%2FJLR.M400102-JLR200

Identification of a nuclear receptor for bile acids

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400102-JLR200

Bile acids: natural ligands for an orphan nuclear receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400102-JLR200

Human bile salt export pump promoter is transactivated by the farnesoid X receptor/bile acid receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400102-JLR200

Regulation of multidrug resistance-associated protein 2 (ABCC2) by the nuclear receptors pregnane X receptor, farnesoid X-activated receptor, and constitutive androstane receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400102-JLR200

Activation of the nuclear receptor LXR by oxysterols defines a new hormone response pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400102-JLR200

27-hydroxycholesterol is an endogenous ligand for liver X receptor in cholesterol-loaded cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400102-JLR200

An oxysterol signalling pathway mediated by the nuclear receptor LXR alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400102-JLR200

Defects of Bile Acid Synthesis in Zellweger's Syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400102-JLR200

In vivo and vitro studies on formation of bile acids in patients with Zellweger syndrome. Evidence that peroxisomes are of importance in the normal biosynthesis of both cholic and chenodeoxycholic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400102-JLR200

Occurrence of both (25R)- and (25S)-3 alpha,7 alpha,12 alpha-trihydroxy-5 beta-cholestanoic acids in urine from an infant with Zellweger's syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400102-JLR200

Cerebrotendinous xanthomatosis: a defect in mitochondrial 26-hydroxylation required for normal biosynthesis of cholic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400102-JLR200

Bile acid synthesis in cultured human hepatocytes: support for an alternative biosynthetic pathway to cholic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400102-JLR200

Identification of the DNA binding specificity and potential target genes for the farnesoid X-activated receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400102-JLR200

Identification of liver X receptor-retinoid X receptor as an activator of the sterol regulatory element-binding protein 1c gene promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400102-JLR200

In vitro farnesoid X receptor ligand sensor assay using surface plasmon resonance and based on ligand-induced coactivator association

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400102-JLR200

Role of LXRs in control of lipogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400102-JLR200

Lithocholic acid decreases expression of bile salt export pump through farnesoid X receptor antagonist activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400102-JLR200

Identification of CYP3A4 as the major enzyme responsible for 25-hydroxylation of 5beta-cholestane-3alpha,7alpha,12alpha-triol in human liver microsomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400102-JLR200

The farnesoid X receptor controls gene expression in a ligand- and promoter-selective fashion

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400102-JLR200

Bile acid profiles in peroxisomal 3-oxoacyl-coenzyme A thiolase deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400102-JLR200

Definition of a novel growth factor-dependent signal cascade for the suppression of bile acid biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400102-JLR200

Loss of nuclear receptor SHP impairs but does not eliminate negative feedback regulation of bile acid synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400102-JLR200

Redundant pathways for negative feedback regulation of bile acid production

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400102-JLR200

Side chain hydroxylations in bile acid biosynthesis catalyzed by CYP3A are markedly up-regulated in Cyp27-/- mice but not in cerebrotendinous xanthomatosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400102-JLR200

Disruption of the sterol 27-hydroxylase gene in mice results in hepatomegaly and hypertriglyceridemia. Reversal by cholic acid feeding.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400102-JLR200

Markedly reduced bile acid synthesis but maintained levels of cholesterol and vitamin D metabolites in mice with disrupted sterol 27-hydroxylase gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400102-JLR200

Bile alcohol profiles in bile, urine, and feces of a patient with cerebrotendinous xanthomatosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400102-JLR200

Structural basis for bile acid binding and activation of the nuclear receptor FXR

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400102-JLR200

Structure-activity relationship of bile acids and bile acid analogs in regard to FXR activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400102-JLR200

FOR, a novel orphan nuclear receptor related to farnesoid X receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400102-JLR200

10.1194/JLR.M400102-JLR200

21 January 2018

Identifiers

DOI

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7 December 2017

1 reference