(Q44905276)

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11beta-Hydroxysteroid dehydrogenase Type 1: genetic polymorphisms are associated with Type 2 diabetes in Pima Indians independently of obesity and expression in adipocyte and muscle

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

7 December 2017

11beta-Hydroxysteroid dehydrogenase Type 1: genetic polymorphisms are associated with Type 2 diabetes in Pima Indians independently of obesity and expression in adipocyte and muscle (English)

1 reference

Europe PubMed Central

PubMed publication ID

7 December 2017

type-1 diabetes

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type 2 diabetes

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Robert S Lindsay

3

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Europe PubMed Central

PubMed publication ID

7 December 2017

Clifton Bogardus

6

object named as

C Bogardus

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Europe PubMed Central

PubMed publication ID

7 December 2017

author name string

S Nair

1

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Europe PubMed Central

PubMed publication ID

7 December 2017

Y H Lee

2

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Europe PubMed Central

PubMed publication ID

7 December 2017

B R Walker

4

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Europe PubMed Central

PubMed publication ID

7 December 2017

P A Tataranni

5

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Europe PubMed Central

PubMed publication ID

7 December 2017

L J Baier

7

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Europe PubMed Central

PubMed publication ID

7 December 2017

P A Permana

8

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Europe PubMed Central

PubMed publication ID

7 December 2017

publication date

20 May 2004

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Europe PubMed Central

PubMed publication ID

7 December 2017

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Europe PubMed Central

PubMed publication ID

7 December 2017

47

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Europe PubMed Central

PubMed publication ID

7 December 2017

6

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Europe PubMed Central

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7 December 2017

1088-1095

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Europe PubMed Central

PubMed publication ID

7 December 2017

https://scigraph.springernature.com/pub.10.1007/s00125-004-1407-6

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Subcutaneous adipose 11 beta-hydroxysteroid dehydrogenase type 1 activity and messenger ribonucleic acid levels are associated with adiposity and insulinemia in Pima Indians and Caucasians

1 reference

https://pubmed.ncbi.nlm.nih.gov/15156315

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Abnormal cortisol metabolism and tissue sensitivity to cortisol in patients with glucose intolerance.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15156315

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Body fat distribution and cortisol metabolism in healthy men: enhanced 5beta-reductase and lower cortisol/cortisone metabolite ratios in men with fatty liver

1 reference

https://pubmed.ncbi.nlm.nih.gov/15156315

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MEF2 protein expression, DNA binding specificity and complex composition, and transcriptional activity in muscle and non-muscle cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/15156315

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Type 1 11beta -hydroxysteroid dehydrogenase mediates glucocorticoid activation and insulin release in pancreatic islets

1 reference

https://pubmed.ncbi.nlm.nih.gov/15156315

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Carbenoxolone increases hepatic insulin sensitivity in man: a novel role for 11-oxosteroid reductase in enhancing glucocorticoid receptor activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/15156315

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Improved lipid and lipoprotein profile, hepatic insulin sensitivity, and glucose tolerance in 11beta-hydroxysteroid dehydrogenase type 1 null mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/15156315

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased expression and activity of 11beta-HSD-1 in diabetic islets and prevention with troglitazone

1 reference

https://pubmed.ncbi.nlm.nih.gov/15156315

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

11Beta-hydroxysteroid dehydrogenase 1 in adipocytes: expression is differentiation-dependent and hormonally regulated

1 reference

https://pubmed.ncbi.nlm.nih.gov/15156315

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tissue-specific changes in peripheral cortisol metabolism in obese women: increased adipose 11beta-hydroxysteroid dehydrogenase type 1 activity.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15156315

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Involvement of the homeodomain-containing transcription factor PDX-1 in islet amyloid polypeptide gene transcription

1 reference

https://pubmed.ncbi.nlm.nih.gov/15156315

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunohistochemical localization of type 1 11beta-hydroxysteroid dehydrogenase in human tissues

1 reference

https://pubmed.ncbi.nlm.nih.gov/15156315

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of glucocorticoid receptor alpha and beta isoforms and type I 11beta-hydroxysteroid dehydrogenase expression in human skeletal muscle cells: a key role in the pathogenesis of insulin resistance?

1 reference

https://pubmed.ncbi.nlm.nih.gov/15156315

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IPF1, a homeodomain-containing transactivator of the insulin gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/15156315

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association of the glycogen synthase locus on 19q13 with NIDDM in Pima Indians

1 reference

https://pubmed.ncbi.nlm.nih.gov/15156315

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vivo insulin action is familial characteristic in nondiabetic Pima Indians

1 reference

https://pubmed.ncbi.nlm.nih.gov/15156315

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Influences of glucose loading and of injected insulin on hepatic glucose output

1 reference

https://pubmed.ncbi.nlm.nih.gov/15156315

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differentiation of adipose stromal cells: the roles of glucocorticoids and 11beta-hydroxysteroid dehydrogenase

1 reference

https://pubmed.ncbi.nlm.nih.gov/15156315

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The MEF2A and MEF2D isoforms are differentially regulated in muscle and adipose tissue during states of insulin deficiency

1 reference

https://pubmed.ncbi.nlm.nih.gov/15156315

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Myocyte enhancer factor 2 (MEF2) binding site is essential for C2C12 myotube-specific expression of the rat GLUT4/muscle-adipose facilitative glucose transporter gene.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15156315

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association studies between microsatellite markers within the gene encoding human 11beta-hydroxysteroid dehydrogenase type 1 and body mass index, waist to hip ratio, and glucocorticoid metabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/15156315

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

11beta-hydroxysteroid dehydrogenase type 1 knockout mice show attenuated glucocorticoid-inducible responses and resist hyperglycemia on obesity or stress

1 reference

https://pubmed.ncbi.nlm.nih.gov/15156315

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Use of dual-energy X-ray absorptiometry in obese individuals

1 reference

https://pubmed.ncbi.nlm.nih.gov/15156315

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tissue-specific dysregulation of cortisol metabolism in human obesity

1 reference

https://pubmed.ncbi.nlm.nih.gov/15156315

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Local and systemic impact of transcriptional up-regulation of 11beta-hydroxysteroid dehydrogenase type 1 in adipose tissue in human obesity

1 reference

https://pubmed.ncbi.nlm.nih.gov/15156315

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lack of mutations of type 1 11beta-hydroxysteroid dehydrogenase gene in patients with abdominal obesity

1 reference

https://pubmed.ncbi.nlm.nih.gov/15156315

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of 11beta-hydroxysteroid dehydrogenase type 1 in adipose tissue is not increased in human obesity

1 reference

https://pubmed.ncbi.nlm.nih.gov/15156315

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutations in the genes encoding 11beta-hydroxysteroid dehydrogenase type 1 and hexose-6-phosphate dehydrogenase interact to cause cortisone reductase deficiency

1 reference

https://pubmed.ncbi.nlm.nih.gov/15156315

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cortisol metabolism in human obesity: impaired cortisone-->cortisol conversion in subjects with central adiposity

1 reference

https://pubmed.ncbi.nlm.nih.gov/15156315

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased glucocorticoid receptor expression in human skeletal muscle cells may contribute to the pathogenesis of the metabolic syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/15156315

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A transgenic model of visceral obesity and the metabolic syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/15156315

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Minireview: 11beta-hydroxysteroid dehydrogenase type 1- a tissue-specific amplifier of glucocorticoid action

1 reference

https://pubmed.ncbi.nlm.nih.gov/15156315

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Myocyte enhancer factor 2 (MEF2)-binding site is required for GLUT4 gene expression in transgenic mice. Regulation of MEF2 DNA binding activity in insulin-deficient diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/15156315

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of the mRNA coding for 11beta-hydroxysteroid dehydrogenase type 1 in adipose tissue from obese patients: an in situ hybridization study

1 reference

https://pubmed.ncbi.nlm.nih.gov/15156315

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin-promoter-factor 1 is required for pancreas development in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/15156315

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glucocorticoid-related genetic susceptibility for Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15156315

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An autosomal genomic scan for loci linked to type II diabetes mellitus and body-mass index in Pima Indians

1 reference

https://pubmed.ncbi.nlm.nih.gov/15156315

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of the 11 beta-hydroxysteroid dehydrogenase inhibitor carbenoxolone on insulin sensitivity in men with type 2 diabetes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15156315

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S00125-004-1407-6

1 reference

Europe PubMed Central

PubMed publication ID

7 December 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

7 December 2017

ResearchGate publication ID

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