(Q44925761)

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K252a-potentiation of EGF-induced neurite outgrowth from PC12 cells is not mimicked or blocked by other protein kinase activators or inhibitors

scientific article published on May 26, 1995

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scholarly article

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Europe PubMed Central

PubMed publication ID

7 December 2017

K252a-potentiation of EGF-induced neurite outgrowth from PC12 cells is not mimicked or blocked by other protein kinase activators or inhibitors (English)

1 reference

Europe PubMed Central

PubMed publication ID

7 December 2017

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C. F. Wu

1

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7656414

22 July 2024

B. D. Howard

2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7656414

22 July 2024

language of work or name

1 reference

National Center for Biotechnology Information

PubMed publication ID

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=7656414

22 July 2024

publication date

1 May 1995

1 reference

Europe PubMed Central

PubMed publication ID

7 December 2017

26 May 1995

1 reference

National Center for Biotechnology Information

PubMed publication ID

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=7656414

22 July 2024

number of pages

10

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full work available at URL

https://api.elsevier.com/content/article/PII:016538069500028C?httpAccept=text/xml

1 reference

10.1016/0165-3806(95)00028-C

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22 July 2024

https://api.elsevier.com/content/article/PII:016538069500028C?httpAccept=text/plain

1 reference

10.1016/0165-3806(95)00028-C

https://api.crossref.org/works/10.1016/0165-3806(95)00028-C

22 July 2024

Developmental Brain Research

1 reference

Europe PubMed Central

PubMed publication ID

7 December 2017

86

1 reference

Europe PubMed Central

PubMed publication ID

7 December 2017

1-2

1 reference

Europe PubMed Central

PubMed publication ID

7 December 2017

217-226

1 reference

Europe PubMed Central

PubMed publication ID

7 December 2017

The Wnt-1 (int-1) proto-oncogene is required for development of a large region of the mouse brain

1 reference

24 May 2022

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K-252a, a potent inhibitor of protein kinase C from microbial origin

1 reference

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Differentiation of PC12 phaeochromocytoma cells induced by v-src oncogene

1

1 reference

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1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine-resistant, flat-cell PC12 variants having a partial loss of transformed phenotype.

2

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Microinjection of the ras oncogene protein into PC12 cells induces morphological differentiation

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PC12 variants deficient in catecholamine transport

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Ionic responses and growth stimulation induced by nerve growth factor and epidermal growth factor in rat pheochromocytoma (PC12) cells

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Clonal variants of PC12 pheochromocytoma cells with altered response to nerve growth factor

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Tumor promoter modulation of epidermal growth factor- and nerve growth factor-induced adhesion and growth factor binding of PC-12 pheochromocytoma cells

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Inhibition by cAMP of Ras-dependent activation of Raf.

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A dopaminergic cell line variant resistant to the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine

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Metabolism and effects of epidermal growth factor and related growth factors in mammals

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Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor

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Differential and synergistic actions of nerve growth factor and cyclic AMP in PC12 cells

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The action of nerve growth factor and dibutyryl adenosine cyclic 3':5'- monophosphate on rat pheochromocytoma reveals distinct stages in the mechanisms underlying neurite outgrowth

16

1 reference

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K-252a, a potent protein kinase inhibitor, blocks nerve growth factor-induced neurite outgrowth and changes in the phosphorylation of proteins in PC12h cells

17

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Synergistic effects of cyclic AMP and nerve growth factor on neurite outgrowth and microtubule stability of PC12 cells

18

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Expression of the v-crk oncogene product in PC12 cells results in rapid differentiation by both nerve growth factor- and epidermal growth factor-dependent pathways

19

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Multiple intercellular signalling systems control the development of the Caenorhabditis elegans vulva.

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Nerve growth factor-induced reduction in epidermal growth factor responsiveness and epidermal growth factor receptors in PC12 cells: An aspect of cell differentiation

22

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Nerve growth factor-induced alteration in the response of PC12 pheochromocytoma cells to epidermal growth factor

23

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K-252 compounds, novel and potent inhibitors of protein kinase C and cyclic nucleotide-dependent protein kinases

26

1 reference

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K-252a: a specific inhibitor of the action of nerve growth factor on PC 12 cells

27

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K-252a inhibits the increase in c-fos transcription and the increase in intracellular calcium produced by nerve growth factor in PC12 cells

28

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Trophic stimulation of cultured neurons from neonatal rat brain by epidermal growth factor

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Inhibition of nerve growth factor-induced neurite outgrowth of PC12 cells by a protein kinase inhibitor which does not permeate the cell membrane

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Epidermal growth factor and transforming growth factor-alpha can induce neuronal differentiation of rat pheochromocytoma PC12 cells under particular culture conditions

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Studies and perspectives of protein kinase C.

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Sarcoma viruses carrying ras oncogenes induce differentiation-associated properties in a neuronal cell line

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PC12 cell neuronal differentiation is associated with prolonged p21ras activity and consequent prolonged ERK activity

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The role of cAMP in nerve growth factor-promoted neurite outgrowth in PC12 cells

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Contrasting morphological changes in PC12 flat cells expressing two different forms of exogenous oncogenic ras.

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Protein Phosphorylation

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Activation of Microtubule‐Associated Protein Kinase in PC12D Cells in Response to Both Fibroblast Growth Factor and Epidermal Growth Factor and Concomitant Stimulation of the Outgrowth of Neurites

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The Wnt-1 proto-oncogene induces changes in morphology, gene expression, and growth factor responsiveness in PC12 cells

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The effect of fibroblast growth factor on PC12 cells

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Targeted disruption of the murine int-1 proto-oncogene resulting in severe abnormalities in midbrain and cerebellar development

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Induction of neurite outgrowth by v-src mimics critical aspects of nerve growth factor-induced differentiation

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Sustained activation of the mitogen-activated protein (MAP) kinase cascade may be required for differentiation of PC12 cells. Comparison of the effects of nerve growth factor and epidermal growth factor

45

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EGF triggers neuronal differentiation of PC12 cells that overexpress the EGF receptor

46

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Clonal variants of PC12 pheochromocytoma cells with defects in cAMP-dependent protein kinases induce ornithine decarboxylase in response to nerve growth factor but not to adenosine agonists

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K252a potentiates epidermal growth factor-induced differentiation of PC12 cells

49

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Inhibition of the EGF-activated MAP kinase signaling pathway by adenosine 3',5'-monophosphate

50

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Transforming growth factor alpha and a PC12-derived growth factor induce neurites in PC12 cells and enhance the survival of embryonic brain neurons.

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Identifiers

10.1016/0165-3806(95)00028-C

1 reference

Europe PubMed Central

PubMed publication ID

7 December 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

7 December 2017

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