(Q44957920)

7 December 2017

title

Novel human CYP2A6 alleles confound gene deletion analysis (English)

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7 December 2017

Miki Nakajima

1

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7 December 2017

Ryoko Yoshida

2

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7 December 2017

Tatsuki Fukami

3

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7 December 2017

Howard L McLeod

4

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7 December 2017

Tsuyoshi Yokoi

5

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7 December 2017

language of work or name

English

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publication date

1 July 2004

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7 December 2017

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7 December 2017

volume

569

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7 December 2017

issue

1-3

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7 December 2017

page(s)

75-81

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Identification and characterisation of novel polymorphisms in the CYP2A locus: implications for nicotine metabolism.

7 December 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.05.053

The CYP2A3 gene product catalyzes coumarin 7-hydroxylation in human liver microsomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.05.053

CYP2A6*6, a novel polymorphism in cytochrome p450 2A6, has a single amino acid substitution (R128Q) that inactivates enzymatic activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.05.053

A novel mutant allele of the CYP2A6 gene (CYP2A6*11 ) found in a cancer patient who showed poor metabolic phenotype towards tegafur

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.05.053

Identification of a single nucleotide polymorphism in the TATA box of the CYP2A6 gene: impairment of its promoter activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.05.053

An in vivo pilot study characterizing the new CYP2A6*7, *8, and *10 alleles

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.05.053

Homologous unequal cross-over within the human CYP2A gene cluster as a mechanism for the deletion of the entire CYP2A6 gene associated with the poor metabolizer phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.05.053

Structural characterization of a new variant of the CYP2A6 gene (CYP2A6*1B) apparently diagnosed as heterozygotes of CYP2A6*1A and CYP2A6*4C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.05.053

Characterization of a genotype previously designated as CYP2A6 D-type: CYP2A6*4B, another entire gene deletion allele of the CYP2A6 gene in Japanese

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.05.053

Characterization of a novel CYP2A7/CYP2A6 hybrid allele (CYP2A6*12) that causes reduced CYP2A6 activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.05.053

Deficient cotinine formation from nicotine is attributed to the whole deletion of the CYP2A6 gene in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.05.053

Relationship between interindividual differences in nicotine metabolism and CYP2A6 genetic polymorphism in humans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.05.053

Nicotine metabolism and CYP2A6 allele frequencies in Koreans

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.05.053

Genetic polymorphisms in human CYP2A6 gene causing impaired nicotine metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.05.053

Effects of polymorphism in promoter region of human CYP2A6 gene (CYP2A6*9) on expression level of messenger ribonucleic acid and enzymatic activity in vivo and in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.05.053

Deficient C-oxidation of nicotine continued.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.05.053

Interindividual differences in nicotine metabolism and genetic polymorphisms of human CYP2A6.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.05.053

Nicotine metabolism defect reduces smoking

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.05.053

10.1016/J.FEBSLET.2004.05.053

21 January 2018

Identifiers

DOI

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7 December 2017

1 reference