(Q52277603)

28 April 2018

title

Identification and characterisation of novel polymorphisms in the CYP2A locus: implications for nicotine metabolism. (English)

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28 April 2018

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4

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28 April 2018

author name string

M Oscarson

1

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28 April 2018

R A McLellan

2

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28 April 2018

H Gullstén

3

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28 April 2018

J Benítez

5

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28 April 2018

A Rautio

6

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28 April 2018

H Raunio

7

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28 April 2018

O Pelkonen

8

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28 April 2018

M Ingelman-Sundberg

9

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28 April 2018

language of work or name

English

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publication date

1 October 1999

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28 April 2018

published in

FEBS Letters

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28 April 2018

volume

460

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28 April 2018

issue

2

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28 April 2018

page(s)

321-327

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28 April 2018

Polymorphic human cytochrome P450 enzymes: an opportunity for individualized drug treatment

cites work

1 reference

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Genotyping of human cytochrome P450 2A6 (CYP2A6), a nicotine C-oxidase

21 January 2018

1 reference

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The significance of the homozygous CYP2A6 deletion on nicotine metabolism: a new genotyping method of CYP2A6 using a single PCR-RFLP

21 January 2018

1 reference

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Species differences and interindividual variation in liver microsomal cytochrome P450 2A enzymes: effects on coumarin, dicumarol, and testosterone oxidation

21 January 2018

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A single amino acid substitution (Leu160His) in cytochrome P450 CYP2A6 causes switching from 7-hydroxylation to 3-hydroxylation of coumarin

21 January 2018

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The CYP2A3 gene product catalyzes coumarin 7-hydroxylation in human liver microsomes

21 January 2018

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Nicotine metabolism defect reduces smoking.

21 January 2018

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Maximizing the expression of mammalian cytochrome P-450 monooxygenase activities in yeast cells

21 January 2018

1 reference

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Enhanced in vivo monooxygenase activities of mammalian P450s in engineered yeast cells producing high levels of NADPH-P450 reductase and human cytochrome b5.

21 January 2018

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Chimeras of the human cytochrome P450 1A family produced in yeast. Accumulation in microsomal membranes, enzyme kinetics and stability

21 January 2018

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A simple and sensitive assay of 7-ethoxycoumarin deethylation

21 January 2018

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Genetic variation of CYP2A6, smoking, and risk of cancer.

21 January 2018

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Variability of coumarin 7- and 3-hydroxylation in a Jordanian population is suggestive of a functional polymorphism in cytochrome P450 CYP2A6

21 January 2018

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Roles of CYP2A6 and CYP2B6 in nicotine C-oxidation by human liver microsomes

21 January 2018

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Interindividual variability of coumarin 7-hydroxylation in a Turkish population

21 January 2018

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Comparison of a novel thin-layer chromatographic-fluorescence detection method with a spectrofluorometric method for the determination of 7-hydroxycoumarin in human urine

21 January 2018

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21 January 2018

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Characterisation and PCR-based detection of a CYP2A6 gene deletion found at a high frequency in a Chinese population

21 January 2018

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CYP2A6 gene deletion reduces susceptibility to lung cancer

21 January 2018

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CYP2A6 gene polymorphism and risk of liver cancer and cirrhosis

21 January 2018

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Nomenclature for human CYP2D6 alleles.

21 January 2018

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A combination of mutations in the CYP2D6*17 (CYP2D6Z) allele causes alterations in enzyme function.

21 January 2018

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10.1016/S0014-5793(99)01364-2

7 January 2021

Identifiers

DOI

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28 April 2018

PubMed ID

10544257

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28 April 2018