(Q44978629)

English

Variability in the benzodiazepine response of serotonin 5-HT1A receptor null mice displaying anxiety-like phenotype: evidence for genetic modifiers in the 5-HT-mediated regulation of GABA(A) receptors.

scientific article published in July 2004

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scholarly article

1 reference

Europe PubMed Central

7 December 2017

Variability in the benzodiazepine response of serotonin 5-HT1A receptor null mice displaying anxiety-like phenotype: evidence for genetic modifiers in the 5-HT-mediated regulation of GABA(A) receptors (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6729545&resulttype=core&format=json

12 May 2020

0 references

1 reference

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author name string

Sarah J Bailey

1

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6729545&resulttype=core&format=json

12 May 2020

Miklos Toth

2

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6729545&resulttype=core&format=json

12 May 2020

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publication date

1 July 2004

1 reference

Europe PubMed Central

7 December 2017

Journal of Neuroscience

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6729545&resulttype=core&format=json

12 May 2020

24

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6729545&resulttype=core&format=json

12 May 2020

28

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Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6729545&resulttype=core&format=json

12 May 2020

6343-6351

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6729545&resulttype=core&format=json

12 May 2020

Effects of centrally administered anxiolytic compounds in animal models of anxiety

1 reference

https://pubmed.ncbi.nlm.nih.gov/15254090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Altered emotional states in knockout mice lacking 5-HT1A or 5-HT1B receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/15254090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Decreased GABAA-receptor clustering results in enhanced anxiety and a bias for threat cues.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15254090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The recombinant 5-HT1A receptor: G protein coupling and signalling pathways.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15254090

12 December 2020

based on heuristic

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Benzodiazepine actions mediated by specific gamma-aminobutyric acid(A) receptor subtypes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15254090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genealogies of mouse inbred strains

1 reference

https://pubmed.ncbi.nlm.nih.gov/15254090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MEK inhibitors block BDNF-dependent and -independent expression of GABA(A) receptor subunit mRNAs in cultured mouse cerebellar granule neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/15254090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synchronous postnatal increase in alpha1 and gamma2L GABA(A) receptor mRNAs and high affinity zolpidem binding across three regions of rat brain.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15254090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differences in anxiety-related behaviours and in sensitivity to diazepam in inbred and outbred strains of mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15254090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

SPECT [I-123]iomazenil measurement of the benzodiazepine receptor in panic disorder

1 reference

https://pubmed.ncbi.nlm.nih.gov/15254090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyclic AMP-mediated regulation of GABA(A) receptor subunit expression in mature rat cerebellar granule cells: evidence for transcriptional and translational control

1 reference

https://pubmed.ncbi.nlm.nih.gov/15254090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic inactivation of the Serotonin(1A) receptor in mice results in downregulation of major GABA(A) receptor alpha subunits, reduction of GABA(A) receptor binding, and benzodiazepine-resistant anxiety.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15254090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sedative but not anxiolytic properties of benzodiazepines are mediated by the GABA(A) receptor alpha1 subtype.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15254090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Decreased benzodiazepine receptor binding in prefrontal cortex in combat-related posttraumatic stress disorder

1 reference

https://pubmed.ncbi.nlm.nih.gov/15254090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Behavioural analysis of four mouse strains in an anxiety test battery

1 reference

https://pubmed.ncbi.nlm.nih.gov/15254090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantitative reverse transcription-polymerase chain reaction to study mRNA decay: comparison of endpoint and real-time methods

1 reference

https://pubmed.ncbi.nlm.nih.gov/15254090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular and neuronal substrate for the selective attenuation of anxiety.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15254090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dominant modifier DFNM1 suppresses recessive deafness DFNB26

1 reference

https://pubmed.ncbi.nlm.nih.gov/15254090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differences in anxiety-related behavior and response to diazepam in BALB/cByJ and C57BL/6J strains of mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15254090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Two mouse lines selected for differential sensitivities to beta-carboline-induced seizures are also differentially sensitive to various pharmacological effects of other GABA(A) receptor ligands

1 reference

https://pubmed.ncbi.nlm.nih.gov/15254090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phenotype-genotype relationships in monogenic disease: lessons from the thalassaemias.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15254090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Loss of the major GABA(A) receptor subtype in the brain is not lethal in mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15254090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Triallelic inheritance in Bardet-Biedl syndrome, a Mendelian recessive disorder

1 reference

https://pubmed.ncbi.nlm.nih.gov/15254090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modern views on an ancient chemical: serotonin effects on cell proliferation, maturation, and apoptosis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15254090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Jerky, a protein deficient in a mouse epilepsy model, is associated with translationally inactive mRNA in neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/15254090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular pathways of anxiety revealed by knockout mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/15254090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic basis of anxiety-like behaviour: a critical review

1 reference

https://pubmed.ncbi.nlm.nih.gov/15254090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Serotonin1A receptor acts during development to establish normal anxiety-like behaviour in the adult

1 reference

https://pubmed.ncbi.nlm.nih.gov/15254090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

GABA(A)-benzodiazepine receptor complex sensitivity in 5-HT(1A) receptor knockout mice on a 129/Sv background

1 reference

https://pubmed.ncbi.nlm.nih.gov/15254090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Excitatory actions of GABA increase BDNF expression via a MAPK-CREB-dependent mechanism--a positive feedback circuit in developing neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/15254090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

GABA(A) receptor alpha-1 subunit deletion alters receptor subtype assembly, pharmacological and behavioral responses to benzodiazepines and zolpidem.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15254090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuronal activity and its influence on developmentally regulated GABA(A) receptor expression in cultured mouse cerebellar granule cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/15254090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Contrasting phenotypes of C57BL/6JOlaHsd, 129S2/SvHsd and 129/SvEv mice in two exploration-based tests of anxiety-related behaviour.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15254090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Behavioral and physiological mouse assays for anxiety: a survey in nine mouse strains

1 reference

https://pubmed.ncbi.nlm.nih.gov/15254090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

GABA(A) receptor composition is determined by distinct assembly signals within alpha and beta subunits

1 reference

https://pubmed.ncbi.nlm.nih.gov/15254090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

5-HT1A receptor knockout mouse as a genetic model of anxiety

1 reference

https://pubmed.ncbi.nlm.nih.gov/15254090

12 December 2020

based on heuristic

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Modifier genes and protective alleles in humans and mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/15254090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The distribution of thirteen GABAA receptor subunit mRNAs in the rat brain. III. Embryonic and postnatal development

1 reference

https://pubmed.ncbi.nlm.nih.gov/15254090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

5-HT1A receptor and 5-HT1B receptor knockout mice in stress and anxiety paradigms

1 reference

https://pubmed.ncbi.nlm.nih.gov/15254090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduced serotonin type 1A receptor binding in panic disorder.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15254090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Benzodiazepine receptor sensitivity in panic disorder.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15254090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Benzodiazepine anti-conflict effects in Maudsley reactive (MR/Har) and non-reactive (MNRA/Har) rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/15254090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduced benzodiazepine sensitivity in panic disorder

1 reference

https://pubmed.ncbi.nlm.nih.gov/15254090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of benzodiazepine and GABA antagonists on anticonflict effects of antianxiety drugs injected into the rat amygdala in a water-lick suppression test.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15254090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Further observations on the effects of subhypnotic doses of midazolam in normal volunteers.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15254090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Roles for Serotonin in Neurogenesis1

1 reference

https://pubmed.ncbi.nlm.nih.gov/15254090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differences in benzodiazepine receptor binding in Maudsley reactive and Maudsley non-reactive rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/15254090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Postnatal development and localization of 5-HT1A receptor mRNA in rat forebrain and cerebellum.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15254090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proteins P1, P2, and P0, components of the eukaryotic ribosome stalk. New structural and functional aspects.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15254090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A review of the validity and variability of the elevated plus-maze as an animal model of anxiety

1 reference

https://pubmed.ncbi.nlm.nih.gov/15254090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential synaptic localization of two major gamma-aminobutyric acid type A receptor alpha subunits on hippocampal pyramidal cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/15254090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduced benzodiazepine sensitivity in patients with panic disorder: comparison with patients with obsessive-compulsive disorder and normal subjects.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15254090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fragile X mental retardation protein: nucleocytoplasmic shuttling and association with somatodendritic ribosomes

1 reference

https://pubmed.ncbi.nlm.nih.gov/15254090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

5-HT1a receptors mediate the neurotrophic effect of serotonin on developing dentate granule cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15254090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effects of midazolam and flumazenil on psychomotor function.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15254090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Agonist-Promoted Down-Regulation and Functional Desensitization in Two Naturally Occurring Variants of the Human Serotonin1A Receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/15254090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of the 5-HT1A receptor in development of the neonatal rat brain: preliminary behavioral studies.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15254090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

GABAA-receptor alpha-subunit is an essential prerequisite for receptor formation in vivo.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15254090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cerebral benzodiazepine receptor binding and distribution in generalized anxiety disorder: a fractal analysis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15254090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The benzodiazepine binding site of GABAA receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/15254090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Determinants of pharmacologic treatment failure in panic disorder.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15254090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stabilization of myelin mRNAs as measured in a brain slice system.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15254090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

FMRP associates with polyribosomes as an mRNP, and the I304N mutation of severe fragile X syndrome abolishes this association

1 reference

https://pubmed.ncbi.nlm.nih.gov/15254090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Decreased brain GABA(A)-benzodiazepine receptor binding in panic disorder: preliminary results from a quantitative PET study

1 reference

https://pubmed.ncbi.nlm.nih.gov/15254090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased anxiety of mice lacking the serotonin1A receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/15254090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Novel mutations in the promoter and coding region of the human 5-HT1A receptor gene and association analysis in schizophrenia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15254090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Serotonin receptor 1A knockout: an animal model of anxiety-related disorder

1 reference

https://pubmed.ncbi.nlm.nih.gov/15254090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Elevated anxiety and antidepressant-like responses in serotonin 5-HT1A receptor mutant mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/15254090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.0563-04.2004

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6729545&resulttype=core&format=json

12 May 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6729545&resulttype=core&format=json

12 May 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6729545&resulttype=core&format=json

12 May 2020

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