(Q44979237)

7 December 2017

title

Unique and redundant roles of Smad3 in TGF-beta-mediated regulation of long bone development in organ culture (English)

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7 December 2017

Jesus Alvarez

1

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7 December 2017

Rosa Serra

series ordinal

2

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7 December 2017

publication date

1 August 2004

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7 December 2017

published in

Developmental Dynamics

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7 December 2017

volume

230

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7 December 2017

issue

4

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7 December 2017

page(s)

685-699

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Heteromeric and homomeric interactions correlate with signaling activity and functional cooperativity of Smad3 and Smad4/DPC4

7 December 2017

cites work

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The perichondrium plays an important role in mediating the effects of TGF-beta1 on endochondral bone formation

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7 January 2021

Mice lacking Smad3 show accelerated wound healing and an impaired local inflammatory response

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7 January 2021

TGF-beta 1 prevents hypertrophy of epiphyseal chondrocytes: regulation of gene expression for cartilage matrix proteins and metalloproteases

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Terminal differentiation of chondrocytes in culture is a spontaneous process and is arrested by transforming growth factor-beta 2 and basic fibroblast growth factor in synergy

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7 January 2021

The loss of Smad3 results in a lower rate of bone formation and osteopenia through dysregulation of osteoblast differentiation and apoptosis

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7 January 2021

Genetic analysis of the mammalian transforming growth factor-beta superfamily

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7 January 2021

Bone abnormalities in latent TGF-[beta] binding protein (Ltbp)-3-null mice indicate a role for Ltbp-3 in modulating TGF-[beta] bioavailability

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7 January 2021

Direct binding of Smad3 and Smad4 to critical TGF beta-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene

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7 January 2021

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7 January 2021

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7 January 2021

Opposite effects of osteogenic protein and transforming growth factor beta on chondrogenesis in cultured long bone rudiments.

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7 January 2021

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7 January 2021

Smad2 and 3 mediate transforming growth factor-beta1-induced inhibition of chondrocyte maturation

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7 January 2021

Inhibition of terminal chondrocyte differentiation by bone morphogenetic protein 7 (OP-1) in vitro depends on the periarticular region but is independent of parathyroid hormone-related peptide

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7 January 2021

Terminal differentiation and calcification in rabbit chondrocyte cultures grown in centrifuge tubes: regulation by transforming growth factor beta and serum factors

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

Localization of Smads, the TGF-beta family intracellular signaling components during endochondral ossification

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7 January 2021

Caenorhabditis elegans genes sma-2, sma-3, and sma-4 define a conserved family of transforming growth factor beta pathway components

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7 January 2021

Expression of a truncated, kinase-defective TGF-beta type II receptor in mouse skeletal tissue promotes terminal chondrocyte differentiation and osteoarthritis

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7 January 2021

Parathyroid hormone-related peptide (PTHrP)-dependent and -independent effects of transforming growth factor beta (TGF-beta) on endochondral bone formation

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7 January 2021

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7 January 2021

Smad2 signaling in extraembryonic tissues determines anterior-posterior polarity of the early mouse embryo

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7 January 2021

Failure of egg cylinder elongation and mesoderm induction in mouse embryos lacking the tumor suppressor smad2.

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7 January 2021

Mechanism of activation of the TGF-beta receptor

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7 January 2021

Targeted disruption of SMAD3 results in impaired mucosal immunity and diminished T cell responsiveness to TGF-beta

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7 January 2021

TGF-beta/Smad3 signals repress chondrocyte hypertrophic differentiation and are required for maintaining articular cartilage

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7 January 2021

Mammalian dwarfins are phosphorylated in response to transforming growth factor beta and are implicated in control of cell growth

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7 January 2021

Receptor-associated Mad homologues synergize as effectors of the TGF-beta response

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7 January 2021

Smad3 mutant mice develop metastatic colorectal cancer

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7 January 2021

Identifiers

DOI

10.1002/DVDY.20100

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7 December 2017

1 reference