(Q44982141)

7 December 2017

Definition of protein kinase sequence motifs that trigger high affinity binding of Hsp90 and Cdc37. (English)

1 reference

7 December 2017

Thomas Prince

1

1 reference

PubMed ID

15258137

7 December 2017

Robert L Matts

series ordinal

2

1 reference

PubMed ID

15258137

7 December 2017

language of work or name

English

0 references

publication date

17 July 2004

1 reference

Journal of Biological Chemistry

7 December 2017

7

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based on heuristic

inferred from page(s)

published in

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7 December 2017

279

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7 December 2017

39975-39981

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7 December 2017

38

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Regulation of signaling protein function and trafficking by the hsp90/hsp70-based chaperone machinery

7 December 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406882200

Heat-shock protein 90, a chaperone for folding and regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406882200

Hsp90: chaperoning signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406882200

A conserved proline in the hsp90 binding region of the glucocorticoid receptor is required for hsp90 heterocomplex stabilization and receptor signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406882200

Mutations at positions 547-553 of rat glucocorticoid receptors reveal that hsp90 binding requires the presence, but not defined composition, of a seven-amino acid sequence at the amino terminus of the ligand binding domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406882200

Binding of hsp90 to the glucocorticoid receptor requires a specific 7-amino acid sequence at the amino terminus of the hormone-binding domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406882200

Involvement of Hsp90 in signaling and stability of 3-phosphoinositide-dependent kinase-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406882200

Modulation of Akt kinase activity by binding to Hsp90

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406882200

Folding requirements of the ligand-binding domain of the human mineralocorticoid receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406882200

Identification of a conserved sequence motif that promotes Cdc37 and cyclin D1 binding to Cdk4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406882200

Two chaperone sites in Hsp90 differing in substrate specificity and ATP dependence

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406882200

Cdc37 goes beyond Hsp90 and kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406882200

Cdc37 is a molecular chaperone with specific functions in signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406882200

Mammalian p50Cdc37 is a protein kinase-targeting subunit of Hsp90 that binds and stabilizes Cdk4

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406882200

p50(cdc37) acting in concert with Hsp90 is required for Raf-1 function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406882200

p50(Cdc37) can buffer the temperature-sensitive properties of a mutant of Hck.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406882200

Hsp90 regulates p50(cdc37) function during the biogenesis of the activeconformation of the heme-regulated eIF2 alpha kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406882200

Functional Dissection of Cdc37: Characterization of Domain Structure and Amino Acid Residues Critical for Protein Kinase Binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406882200

Identification and characterization of Harc, a novel Hsp90-associating relative of Cdc37

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406882200

Phosphorylation of serine 13 is required for the proper function of the Hsp90 co-chaperone, Cdc37.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406882200

High Affinity Binding of Hsp90 Is Triggered by Multiple Discrete Segments of Its Kinase Clients

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406882200

Inhibition of heat shock protein HSP90-pp60v-src heteroprotein complex formation by benzoquinone ansamycins: essential role for stress proteins in oncogenic transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406882200

Crystal structure of an Hsp90-geldanamycin complex: targeting of a protein chaperone by an antitumor agent

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406882200

Identification and structural characterization of the ATP/ADP-binding site in the Hsp90 molecular chaperone

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406882200

The heat shock protein 90 antagonist novobiocin interacts with a previously unrecognized ATP-binding domain in the carboxyl terminus of the chaperone

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406882200

Novobiocin induces a distinct conformation of Hsp90 and alters Hsp90-cochaperone-client interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406882200

p50(cdc37) is a nonexclusive Hsp90 cohort which participates intimately in Hsp90-mediated folding of immature kinase molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406882200

Hop modulates Hsp70/Hsp90 interactions in protein folding

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406882200

Effect of geldanamycin on the kinetics of chaperone-mediated renaturation of firefly luciferase in rabbit reticulocyte lysate

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406882200

Evidence that protein phosphatase 5 functions to negatively modulate the maturation of the Hsp90-dependent heme-regulated eIF2alpha kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406882200

Functional messenger RNAs are produced by SP6in vitrotranscription of cloned cDNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406882200

Hsp90 is obligatory for the heme-regulated eIF-2alpha kinase to acquire and maintain an activable conformation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406882200

TNF-induced recruitment and activation of the IKK complex require Cdc37 and Hsp90

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406882200

p50(cdc37) binds directly to the catalytic domain of Raf as well as to a site on hsp90 that is topologically adjacent to the tetratricopeptide repeat binding site

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406882200

Akt forms an intracellular complex with heat shock protein 90 (Hsp90) and Cdc37 and is destabilized by inhibitors of Hsp90 function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406882200

Crystal structure of cyclin-dependent kinase 2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406882200

Three-dimensional structure of the tyrosine kinase c-Src

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406882200

Crystal structures of c-Src reveal features of its autoinhibitory mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406882200

Crystal structure of Hck in complex with a Src family-selective tyrosine kinase inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406882200

Intramolecular regulatory interactions in the Src family kinase Hck probed by mutagenesis of a conserved tryptophan residue.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406882200

Insights into Src kinase functions: structural comparisons

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406882200

Steroid receptor interactions with heat shock protein and immunophilin chaperones

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406882200

21 January 2018

Identifiers

DOI

10.1074/JBC.M406882200

1 reference

7 December 2017

1 reference

PubMed ID

15258137