(Q45037100)

8 December 2017

title

Enhanced rate of cleavage at Arg-306 and Arg-506 in coagulation factor Va by Gla domain-mutated human-activated protein C. (English)

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8 December 2017

Yong-Hui Sun

1

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8 December 2017

Sinh Tran

series ordinal

2

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8 December 2017

Eva A Norstrøm

series ordinal

3

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8 December 2017

Björn Dahlbäck

series ordinal

4

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8 December 2017

language of work or name

English

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publication date

27 August 2004

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Journal of Biological Chemistry

8 December 2017

published in

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8 December 2017

volume

279

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8 December 2017

issue

46

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8 December 2017

page(s)

47528-47535

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The molecular basis of blood coagulation

8 December 2017

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407366200

Enhancement of vitamin-K-dependent protein function by modification of the gamma-carboxyglutamic acid domain: studies of protein C and factor VII.

21 January 2018

1 reference

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Cofactor proteins in the assembly and expression of blood clotting enzyme complexes

21 January 2018

1 reference

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Effects of protein S and factor Xa on peptide bond cleavages during inactivation of factor Va and factor VaR506Q by activated protein C

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407366200

Factor V and thrombotic disease: description of a janus-faced protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407366200

Peptide bond cleavages and loss of functional activity during inactivation of factor Va and factor VaR506Q by activated protein C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407366200

Importance of protein S and phospholipid for activated protein C-mediated cleavages in factor Va.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407366200

Binding site for blood coagulation factor Xa involving residues 311-325 in factor Va.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407366200

Interdomain engineered disulfide bond permitting elucidation of mechanisms of inactivation of coagulation factor Va by activated protein C

21 January 2018

1 reference

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Functional characterization of recombinant FV Hong Kong and FV Cambridge.

21 January 2018

1 reference

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Comparison of naturally occurring vitamin K-dependent proteins: correlation of amino acid sequences and membrane binding properties suggests a membrane contact site

21 January 2018

1 reference

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Enhancing the activity of protein C by mutagenesis to improve the membrane-binding site: studies related to proline-10.

21 January 2018

1 reference

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Enhancement of human protein C function by site-directed mutagenesis of the gamma-carboxyglutamic acid domain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407366200

Gla domain-mutated human protein C exhibiting enhanced anticoagulant activity and increased phospholipid binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407366200

Purification of human vitamin K-dependent protein S and its limited proteolysis by thrombin

21 January 2018

1 reference

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Inherited resistance to activated protein C is corrected by anticoagulant cofactor activity found to be a property of factor V.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407366200

Factor Va is inactivated by activated protein C in the absence of cleavage sites at Arg-306, Arg-506, and Arg-679.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407366200

Efficacy and safety of recombinant human activated protein C for severe sepsis

21 January 2018

1 reference

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Gene expression profile of antithrombotic protein c defines new mechanisms modulating inflammation and apoptosis

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1074/JBC.M407366200

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8 December 2017

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