(Q45044236)

8 December 2017

title

Glutathione S-transferase Pi has at least three distinguishable xenobiotic substrate sites close to its glutathione-binding site (English)

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8 December 2017

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2

Roberta F Colman

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8 December 2017

Luis A Ralat

1

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8 December 2017

language of work or name

English

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publication date

3 September 2004

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Journal of Biological Chemistry

8 December 2017

published in

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8 December 2017

volume

279

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8 December 2017

issue

48

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8 December 2017

page(s)

50204-50213

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Nomenclature for human glutathione transferases

8 December 2017

cites work

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Identification of a highly reactive sulphydryl group in human placental glutathione transferase by a site-directed fluorescent reagent.

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Cysteine-86 is not needed for the enzymic activity of glutathione S-transferase 3-3

21 January 2018

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Tyrosine-7 is an essential residue for the catalytic activity of human class PI glutathione S-transferase: chemical modification and site-directed mutagenesis studies

21 January 2018

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Tyrosine-7 in human class Pi glutathione S-transferase is important for lowering the pKa of the thiol group of glutathione in the enzyme-glutathione complex

21 January 2018

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Structure and function of the xenobiotic substrate binding site of a glutathione S-transferase as revealed by X-ray crystallographic analysis of product complexes with the diastereomers of 9-(S-glutathionyl)-10-hydroxy-9,10-dihydrophenanthrene

21 January 2018

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Structure and function of the xenobiotic substrate-binding site and location of a potential non-substrate-binding site in a class pi glutathione S-transferase

21 January 2018

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Three-dimensional structure, catalytic properties, and evolution of a sigma class glutathione transferase from squid, a progenitor of the lens S-crystallins of cephalopods

21 January 2018

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Structure determination and refinement of human alpha class glutathione transferase A1-1, and a comparison with the Mu and Pi class enzymes

21 January 2018

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Glutathione S-transferase pi immunostaining of cisplatin-resistant ovarian cancer cells in ascites.

21 January 2018

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Coordinated action of glutathione S-transferases (GSTs) and multidrug resistance protein 1 (MRP1) in antineoplastic drug detoxification. Mechanism of GST A1-1- and MRP1-associated resistance to chlorambucil in MCF7 breast carcinoma cells

21 January 2018

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Monobromobimane occupies a distinct xenobiotic substrate site in glutathione S‐transferase π

21 January 2018

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Reversible conjugation of isothiocyanates with glutathione catalyzed by human glutathione transferases

21 January 2018

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Isothiocyanates as substrates for human glutathione transferases: structure-activity studies.

21 January 2018

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Forward and reverse catalysis and product sequestration by human glutathione S-transferases in the reaction of GSH with dietary aralkyl isothiocyanates

21 January 2018

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47 A centrifuged-column procedure for the measurement of ligand binding by beef heart F1

21 January 2018

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A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

21 January 2018

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Characterization of cysteine residues of glutathione S-transferase P: evidence for steric hindrance of substrate binding by a bulky adduct to cysteine 47

21 January 2018

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Site-directed mutagenesis of human glutathione transferase P1-1. Spectral, kinetic, and structural properties of Cys-47 and Lys-54 mutants

21 January 2018

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Kinetic characterization of native and cysteine 112-modified glutathione S-transferase A1-1: reassessment of nonsubstrate ligand binding

21 January 2018

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Spectrofluorimetric assessment of the surface hydrophobicity of proteins

21 January 2018

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Characterization of bromosulphophthalein binding to human glutathione S-transferase A1-1: thermodynamics and inhibition kinetics

21 January 2018

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Molecular determinants for ATP-binding in proteins: a data mining and quantum chemical analysis

21 January 2018

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The structures of human glutathione transferase P1-1 in complex with glutathione and various inhibitors at high resolution

21 January 2018

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Evidence for an induced-fit mechanism operating in pi class glutathione transferases

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M407445200

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8 December 2017

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