(Q45049923)

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3beta-20beta-dihydroxy-5alpha-pregnane (UC1011) antagonism of the GABA potentiation and the learning impairment induced in rats by allopregnanolone

scientific article published in September 2004

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Europe PubMed Central

PubMed publication ID

8 December 2017

3beta-20beta-dihydroxy-5alpha-pregnane (UC1011) antagonism of the GABA potentiation and the learning impairment induced in rats by allopregnanolone (English)

1 reference

Europe PubMed Central

PubMed publication ID

8 December 2017

Torbjörn C. Bäckström

5

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Torbjorn Backstrom

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Europe PubMed Central

PubMed publication ID

8 December 2017

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Sahruh Turkmen

1

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Europe PubMed Central

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8 December 2017

Per Lundgren

2

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Europe PubMed Central

PubMed publication ID

8 December 2017

Vita Birzniece

3

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Europe PubMed Central

PubMed publication ID

8 December 2017

Elisabeth Zingmark

4

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Europe PubMed Central

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8 December 2017

Inga-Maj Johansson

6

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Europe PubMed Central

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8 December 2017

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publication date

1 September 2004

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Europe PubMed Central

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8 December 2017

European Journal of Neuroscience

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Europe PubMed Central

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8 December 2017

20

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Europe PubMed Central

PubMed publication ID

8 December 2017

6

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Europe PubMed Central

PubMed publication ID

8 December 2017

1604-1612

1 reference

Europe PubMed Central

PubMed publication ID

8 December 2017

Neurosteroids: a new brain function?

1 reference

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Anxiolytic effects of 3α-hydroxy-5α[β]-pregnan-20-one: endogenous metabolites of progesterone that are active at the GABAA receptor

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Progesterone, 5alpha-pregnane-3,20-dione and 3alpha-hydroxy-5alpha-pregnane-20-one in specific regions of the human female brain in different endocrine states

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Alpha2C-adrenoceptor overexpression disrupts execution of spatial and non-spatial search patterns.

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Motherhood and memory: a review

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Apolipoprotein E knockout mice display procedural deficits in the Morris water maze: analysis of learning strategies in three versions of the task.

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Neurosteroids: biosynthesis and function of these novel neuromodulators

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Physiological modulation of GABA(A) receptor plasticity by progesterone metabolites.

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Applications of the Morris water maze in the study of learning and memory

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gamma-aminobutyric acidA receptor regulation: heterologous uncoupling of modulatory site interactions induced by chronic steroid, barbiturate, benzodiazepine, or GABA treatment in culture

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Neurosteroids Affect Spatial/Reference, Working, and Long-Term Memory of Female Rats

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Circulating levels of allopregnanolone in humans: gender, age, and endocrine influences

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Allopregnanolone modulates spontaneous GABA release via presynaptic Cl- permeability in rat preoptic nerve terminals

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Allopregnanolone inhibits learning in the Morris water maze

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Convulsant actions of the neurosteroid pregnenolone sulfate in mice

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Prolonged intracerebroventricular infusion of neurosteroids affects cognitive performances in the mouse.

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Serum allopregnanolone levels in pregnant women: changes during pregnancy, at delivery, and in hypertensive patients.

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Allopregnanolone-stimulated GABA-mediated chloride ion flux is inhibited by 3beta-hydroxy-5alpha-pregnan-20-one (isoallopregnanolone).

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Mood, neuropsychological function and cognitions in premenstrual dysphoric disorder.

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Infusion of neurosteroids into the nucleus basalis magnocellularis affects cognitive processes in the rat.

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21 January 2018

Differential effects of benzodiazepine receptor agonists on hippocampal long-term potentiation and spatial learning in the Morris water maze.

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Chlordiazepoxide, an anxiolytic benzodiazepine, impairs place navigation in rats.

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An update on GABAA receptors

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Developments of a water-maze procedure for studying spatial learning in the rat

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Place navigation impaired in rats with hippocampal lesions

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Radioimmunoassay of 3 alpha-hydroxy-5 alpha-pregnan-20-one in rat and human plasma.

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21 January 2018

Stress and glucocorticoids impair retrieval of long-term spatial memory

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The effects of neurosteroids on acquisition and retention of a modified passive-avoidance learning task in mice

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21 January 2018

Sex and estrous cycle-dependent changes in neurosteroid and benzodiazepine effects on food consumption and plus-maze learning behaviors in rats.

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21 January 2018

Reversible neural inactivation reveals hippocampal participation in several memory processes

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Water maze performance, exploratory activity, inhibitory avoidance and hippocampal plasticity in aged superior and inferior learners

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Estrogen plus progestin and the incidence of dementia and mild cognitive impairment in postmenopausal women: the Women's Health Initiative Memory Study: a randomized controlled trial

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Neuroactive steroids and the constraint of memory.

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Patients with premenstrual syndrome have a different sensitivity to a neuroactive steroid during the menstrual cycle compared to control subjects

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Reduced benzodiazepine sensitivity in patients with premenstrual syndrome: a pilot study.

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Cognitive properties of sedation agents: comparison of the effects of nitrous oxide and midazolam on memory and mood.

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Effect of acute ethanol administration and acute allopregnanolone administration on spontaneous hippocampal pyramidal cell neural activity

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Neurosteroids in learning and memory processes

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Lorazepam impairs both visual and auditory perceptual priming.

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The inhibitory effects of allopregnanolone and pregnanolone on the population spike, evoked in the rat hippocampal CA1 stratum pyramidale in vitro, can be blocked selectively by epiallopregnanolone.

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Neuroactive steroids and central nervous system disorders.

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Anxiolytic activity of the progesterone metabolite 5α-pregnan-3α-ol-20-one

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Hippocampal corticosteroid receptor mRNA expression and spatial learning in the aged Wistar rat.

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Evaluation and comparison of the pharmacokinetic and pharmacodynamic properties of allopregnanolone and pregnanolone at induction of anaesthesia in the male rat.

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10.1111/J.1460-9568.2004.03610.X

1 reference

Europe PubMed Central

PubMed publication ID

8 December 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

8 December 2017

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