(Q45057099)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15364911%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

title

Functional consequences of alpha-synuclein tyrosine nitration: diminished binding to lipid vesicles and increased fibril formation (English)

1 reference

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1 January 2020

1 reference

2

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1 January 2020

author name string

Roberto Hodara

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15364911%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

Benoit I Giasson

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15364911%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

Amanda J Mishizen-Eberz

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15364911%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

David R Lynch

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15364911%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

Virginia M-Y Lee

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15364911%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

Harry Ischiropoulos

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15364911%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

language of work or name

English

0 references

publication date

9 September 2004

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15364911%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

1 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15364911%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

volume

279

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15364911%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

issue

46

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15364911%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

page(s)

47746-47753

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15364911%20AND%20SRC:MED&resulttype=core&format=json

The precursor protein of non-A beta component of Alzheimer's disease amyloid is a presynaptic protein of the central nervous system

1 January 2020

cites work

1 reference

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Characterization of a novel protein regulated during the critical period for song learning in the zebra finch.

21 January 2018

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Identification of two distinct synucleins from human brain

21 January 2018

1 reference

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Stabilization of alpha-synuclein secondary structure upon binding to synthetic membranes

21 January 2018

1 reference

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Regulation of phospholipase D2: selective inhibition of mammalian phospholipase D isoenzymes by alpha- and beta-synucleins

21 January 2018

1 reference

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Chaperone-like activity of synucleins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408906200

Structural changes in alpha-synuclein affect its chaperone-like activity in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408906200

Structural and functional implications of C-terminal regions of alpha-synuclein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408906200

Alpha-synuclein in Lewy bodies

21 January 2018

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alpha-Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with lewy bodies

21 January 2018

1 reference

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Glial cytoplasmic inclusions in white matter oligodendrocytes of multiple system atrophy brains contain insoluble alpha-synuclein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408906200

Oxidative dimer formation is the critical rate-limiting step for Parkinson's disease alpha-synuclein fibrillogenesis

21 January 2018

1 reference

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Acceleration of oligomerization, not fibrillization, is a shared property of both alpha-synuclein mutations linked to early-onset Parkinson's disease: implications for pathogenesis and therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408906200

Inhibition of fibrillization and accumulation of prefibrillar oligomers in mixtures of human and mouse alpha-synuclein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408906200

Alpha-synuclein, especially the Parkinson's disease-associated mutants, forms pore-like annular and tubular protofibrils

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408906200

Effects of oxidative and nitrative challenges on alpha-synuclein fibrillogenesis involve distinct mechanisms of protein modifications

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408906200

Nitration inhibits fibrillation of human α‐synuclein in vitro by formation of soluble oligomers

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408906200

Interaction of human alpha-Synuclein and Parkinson's disease variants with phospholipids. Structural analysis using site-directed mutagenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408906200

Distinct cleavage patterns of normal and pathologic forms of alpha-synuclein by calpain I in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408906200

Cytochrome c nitration by peroxynitrite.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408906200

Endoproteolytic activity of the proteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408906200

Distinct roles of the N-terminal-binding domain and the C-terminal-solubilizing domain of alpha-synuclein, a molecular chaperone

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408906200

Aggregated and monomeric alpha-synuclein bind to the S6' proteasomal protein and inhibit proteasomal function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408906200

Proteasomal function is impaired in substantia nigra in Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408906200

α-Synuclein Is Degraded by Both Autophagy and the Proteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408906200

Lysosomal malfunction accompanies alpha-synuclein aggregation in a progressive mouse model of Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408906200

Parkin cleaves intracellular alpha-synuclein inclusions via the activation of calpain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408906200

Ubiquitination of a new form of alpha-synuclein by parkin from human brain: implications for Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408906200

Kinetic stabilization of the alpha-synuclein protofibril by a dopamine-alpha-synuclein adduct

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408906200

Methionine oxidation inhibits fibrillation of human alpha-synuclein in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408906200

Phosphorylation of alpha-synuclein characteristic of synucleinopathy lesions is recapitulated in alpha-synuclein transgenic Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408906200

Role of individual methionines in the fibrillation of methionine-oxidized alpha-synuclein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408906200

Annular alpha-synuclein protofibrils are produced when spherical protofibrils are incubated in solution or bound to brain-derived membranes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408906200

The association of alpha-synuclein with membranes affects bilayer structure, stability, and fibril formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408906200

Vesicle permeabilization by protofibrillar alpha-synuclein is sensitive to Parkinson's disease-linked mutations and occurs by a pore-like mechanism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408906200

Vesicle permeabilization by protofibrillar alpha-synuclein: implications for the pathogenesis and treatment of Parkinson's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408906200

Alpha-synuclein has a high affinity for packing defects in a bilayer membrane: a thermodynamics study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408906200

Binding of alpha-synuclein to brain vesicles is abolished by familial Parkinson's disease mutation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408906200

Lipid binding inhibits alpha-synuclein fibril formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408906200

Membrane binding and self-association of alpha-synucleins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408906200

The ubiquitin pathway in Parkinson's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408906200

Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408906200

21 January 2018

Identifiers

DOI

10.1074/JBC.M408906200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15364911%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

1 reference