(Q45065860)

9 December 2017

title

A phenylalanine zipper mediates APS dimerization (English)

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9 December 2017

Sirano Dhe-Paganon

1

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9 December 2017

Eric D Werner

2

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9 December 2017

Masahiro Nishi

3

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9 December 2017

Lone Hansen

4

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9 December 2017

Young-In Chi

5

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9 December 2017

Steven E Shoelson

6

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9 December 2017

publication date

19 September 2004

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Nature Structural & Molecular Biology

9 December 2017

published in

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9 December 2017

volume

11

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9 December 2017

issue

10

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9 December 2017

page(s)

968-974

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Regulation of signal transduction and signal diversity by receptor oligomerization

9 December 2017

cites work

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Switching signals on or off by receptor dimerization

21 January 2018

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Dimerization as a regulatory mechanism in signal transduction

21 January 2018

1 reference

Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins

21 January 2018

1 reference

Cloning and characterization of APS, an adaptor molecule containing PH and SH2 domains that is tyrosine phosphorylated upon B-cell receptor stimulation

21 January 2018

1 reference

Cloning and characterization of human Lnk, an adaptor protein with pleckstrin homology and Src homology 2 domains that can inhibit T cell activation

21 January 2018

1 reference

Characterization of Lnk. An adaptor protein expressed in lymphocytes

21 January 2018

1 reference

PSM, an insulin-dependent, pro-rich, PH, SH2 domain containing partner of the insulin receptor

21 January 2018

1 reference

Platelet-derived growth factor (PDGF) stimulates the association of SH2-Bbeta with PDGF receptor and phosphorylation of SH2-Bbeta

21 January 2018

1 reference

Identification and characterization of novel substrates of Trk receptors in developing neurons

21 January 2018

1 reference

SH2-Balpha is an insulin-receptor adapter protein and substrate that interacts with the activation loop of the insulin-receptor kinase

21 January 2018

1 reference

Identification of the APS protein as a novel insulin receptor substrate

21 January 2018

1 reference

Insulin-like growth factor-I receptor and insulin receptor association with a Src homology-2 domain-containing putative adapter

21 January 2018

1 reference

The adapter protein APS associates with the multifunctional docking sites Tyr-568 and Tyr-936 in c-Kit

21 January 2018

1 reference

Identification of SH2-Bbeta as a substrate of the tyrosine kinase JAK2 involved in growth hormone signaling

21 January 2018

1 reference

Identification of SH2-bbeta as a potent cytoplasmic activator of the tyrosine kinase Janus kinase 2.

21 January 2018

1 reference

Molecular cloning of the mouse APS as a member of the Lnk family adaptor proteins

21 January 2018

1 reference

APS, an adaptor protein containing Pleckstrin homology (PH) and Src homology-2 (SH2) domains inhibits the JAK-STAT pathway in collaboration with c-Cbl

21 January 2018

1 reference

Adapter protein with a pleckstrin homology (PH) and an Src homology 2 (SH2) domain (APS) and SH2-B enhance insulin-receptor autophosphorylation, extracellular-signal-regulated kinase and phosphoinositide 3-kinase-dependent signalling

21 January 2018

1 reference

SH2-B family members differentially regulate JAK family tyrosine kinases

21 January 2018

1 reference

The APS adapter protein couples the insulin receptor to the phosphorylation of c-Cbl and facilitates ligand-stimulated ubiquitination of the insulin receptor

21 January 2018

1 reference

APS facilitates c-Cbl tyrosine phosphorylation and GLUT4 translocation in response to insulin in 3T3-L1 adipocytes

21 January 2018

1 reference

Control of B cell production by the adaptor protein lnk. Definition Of a conserved family of signal-modulating proteins

21 January 2018

1 reference

Cytokine signaling and hematopoietic homeostasis are disrupted in Lnk-deficient mice

21 January 2018

1 reference

SH2-B is required for both male and female reproduction

21 January 2018

1 reference

Increased Insulin Sensitivity and Hypoinsulinemia in APS Knockout Mice

21 January 2018

1 reference

Structural basis for recruitment of the adaptor protein APS to the activated insulin receptor

21 January 2018

1 reference

SH2-B and APS are multimeric adapters that augment TrkA signaling

21 January 2018

1 reference

De novo design of helical bundles as models for understanding protein folding and function.

21 January 2018

1 reference

Aromatic-aromatic interaction: a mechanism of protein structure stabilization

21 January 2018

1 reference

Autophosphorylation within insulin receptor .beta.-subunits can occur as an intramolecular process

21 January 2018

1 reference

Self-assembly of designed antimicrobial peptides in solution and micelles

21 January 2018

1 reference

Processing of X-ray diffraction data collected in oscillation mode

21 January 2018

1 reference

Automated MAD and MIR structure solution

21 January 2018

1 reference

The CCP4 suite: programs for protein crystallography

21 January 2018

1 reference

Improved methods for building protein models in electron density maps and the location of errors in these models

21 January 2018

1 reference

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

21 January 2018

1 reference

Size-Distribution Analysis of Macromolecules by Sedimentation Velocity Ultracentrifugation and Lamm Equation Modeling

21 January 2018

1 reference

Characterization of an interaction between insulin receptor substrate 1 and the insulin receptor by using the two-hybrid system

21 January 2018

1 reference

Yeast forward and reverse 'n'-hybrid systems

21 January 2018

1 reference

Protein folding and association: insights from the interfacial and thermodynamic properties of hydrocarbons

21 January 2018

1 reference

SH2-B is required for nerve growth factor-induced neuronal differentiation

21 January 2018

1 reference

Novel approach to phasing proteins: derivatization by short cryo-soaking with halides

31 March 2020

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31 March 2020

Identifiers

DOI

10.1038/NSMB829

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Dimensions Publication ID

9 December 2017

1026466876

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