(Q45069870)

9 December 2017

title

Pyruvate prevents cardiac dysfunction and AMP-activated protein kinase activation by hydrogen peroxide in isolated rat hearts (English)

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9 December 2017

Richard Schulz

6

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author name string

Hernando Leon

1

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9 December 2017

Laura L Atkinson

2

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9 December 2017

Jolanta Sawicka

3

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9 December 2017

Ken Strynadka

4

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9 December 2017

Gary D Lopaschuk

5

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9 December 2017

publication date

1 June 2004

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Canadian Journal of Physiology and Pharmacology

9 December 2017

published in

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9 December 2017

volume

82

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9 December 2017

issue

6

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9 December 2017

page(s)

409-416

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Superoxide generation in directional coronary atherectomy specimens of patients with angina pectoris: important role of NAD(P)H oxidase

9 December 2017

cites work

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Uric acid as radical scavenger and antioxidant in the heart

21 January 2018

1 reference

Alterations in electrical and contractile behavior of isolated cardiomyocytes by hydrogen peroxide: possible ionic mechanisms

21 January 2018

1 reference

Mutations in the gamma(2) subunit of AMP-activated protein kinase cause familial hypertrophic cardiomyopathy: evidence for the central role of energy compromise in disease pathogenesis

21 January 2018

1 reference

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

21 January 2018

1 reference

Pyruvate-enhanced phosphorylation potential and inotropism in normoxic and postischemic isolated working heart. Near-complete prevention of reperfusion contractile failure

21 January 2018

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The regulation of AMP-activated protein kinase by H(2)O(2).

21 January 2018

1 reference

The AMP-activated protein kinase--fuel gauge of the mammalian cell?

21 January 2018

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AMP-activated protein kinase: the energy charge hypothesis revisited

21 January 2018

1 reference

Influence of pyruvate on contractile performance and Ca(2+) cycling in isolated failing human myocardium

21 January 2018

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Characterization of the AMP-activated protein kinase kinase from rat liver and identification of threonine 172 as the major site at which it phosphorylates AMP-activated protein kinase

21 January 2018

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Potentiation of beta-adrenergic inotropic response by pyruvate in failing human myocardium

21 January 2018

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Characterization of 5'AMP-activated protein kinase activity in the heart and its role in inhibiting acetyl-CoA carboxylase during reperfusion following ischemia

21 January 2018

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Constitutively active adenosine monophosphate-activated protein kinase regulates voltage-gated sodium channels in ventricular myocytes

21 January 2018

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The role of SR Ca(2+)-content in blunted inotropic responsiveness of failing human myocardium

21 January 2018

1 reference

Pyruvate: metabolic protector of cardiac performance.

21 January 2018

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Pyruvate restores contractile function and antioxidant defenses of hydrogen peroxide-challenged myocardium

21 January 2018

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Phosphorylation and activation of heart PFK-2 by AMPK has a role in the stimulation of glycolysis during ischaemia

21 January 2018

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Effects of oxygen radicals on substrate oxidation by cardiac myocytes.

21 January 2018

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Evidence that AMP triggers phosphorylation as well as direct allosteric activation of rat liver AMP-activated protein kinase. A sensitive mechanism to protect the cell against ATP depletion

21 January 2018

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Dual regulation of the AMP-activated protein kinase provides a novel mechanism for the control of creatine kinase in skeletal muscle.

21 January 2018

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Ionic mechanism of the effects of hydrogen peroxide in rat ventricular myocytes.

21 January 2018

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Role of protein kinase C in mediating effects of hydrogen peroxide in guinea-pig ventricular myocytes

21 January 2018

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Role of AMP-activated protein kinase in mechanism of metformin action

21 January 2018

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Generation of peroxynitrite contributes to ischemia-reperfusion injury in isolated rat hearts

21 January 2018

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21 January 2018

Identifiers

DOI

10.1139/Y04-050

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9 December 2017

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