(Q45070050)

9 December 2017

title

Interleukin 1beta inhibits CAR-induced expression of hepatic genes involved in drug and bilirubin clearance (English)

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9 December 2017

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Eric Assenat

1

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9 December 2017

Sabine Gerbal-Chaloin

2

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9 December 2017

Dominique Larrey

3

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9 December 2017

Jean Saric

4

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9 December 2017

Jean-Michel Fabre

5

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9 December 2017

Patrick Maurel

6

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9 December 2017

Marie-José Vilarem

7

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9 December 2017

Jean Marc Pascussi

8

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9 December 2017

language of work or name

English

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publication date

1 October 2004

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9 December 2017

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9 December 2017

volume

40

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9 December 2017

issue

4

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9 December 2017

page(s)

951-960

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Regulation of cytochromes P450 during inflammation and infection.

9 December 2017

cites work

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7 January 2021

The role of individual human cytochromes P450 in drug metabolism and clinical response

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7 January 2021

Interleukin-1 beta antagonizes phenobarbital induction of several major cytochromes P450 in adult rat hepatocytes in primary culture

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7 January 2021

Reduction in cytochrome P-450 enzyme expression is associated with repression of CAR (constitutive androstane receptor) and PXR (pregnane X receptor) in mouse liver during the acute phase response

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7 January 2021

Down-regulation of phenobarbital-induced cytochrome P4502B mRNAs and proteins by endotoxin in mice: independence from nitric oxide production by inducible nitric oxide synthase

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7 January 2021

Interleukin-6 negatively regulates the expression of pregnane X receptor and constitutively activated receptor in primary human hepatocytes.

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7 January 2021

Nitric oxide-independent suppression of P450 2C11 expression by interleukin-1beta and endotoxin in primary rat hepatocytes

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7 January 2021

Inflammation-induced cholestasis

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7 January 2021

Sepsis-associated cholestasis

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7 January 2021

Hepatocyte transport of bile acids and organic anions in endotoxemic rats: impaired uptake and secretion

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7 January 2021

The repressed nuclear receptor CAR responds to phenobarbital in activating the human CYP2B6 gene

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7 January 2021

Transcriptional regulation of CYP2C9 gene. Role of glucocorticoid receptor and constitutive androstane receptor

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7 January 2021

Transcriptional regulation of the human CYP3A4 gene by the constitutive androstane receptor

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7 January 2021

Induction of bilirubin clearance by the constitutive androstane receptor (CAR)

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7 January 2021

Regulation of multidrug resistance-associated protein 2 (ABCC2) by the nuclear receptors pregnane X receptor, farnesoid X-activated receptor, and constitutive androstane receptor

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7 January 2021

Differential transactivation by two isoforms of the orphan nuclear hormone receptor CAR

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7 January 2021

Phenobarbital-elicited activation of nuclear receptor CAR in induction of cytochrome P450 genes

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7 January 2021

Transcriptional analysis of the orphan nuclear receptor constitutive androstane receptor (NR1I3) gene promoter: identification of a distal glucocorticoid response element

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7 January 2021

Biochemistry, molecular biology, and physiology of the glucocorticoid receptor

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7 January 2021

Transcriptional cross-talk, the second mode of steroid hormone receptor action

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7 January 2021

Physical association and functional antagonism between the p65 subunit of transcription factor NF-kappa B and the glucocorticoid receptor

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7 January 2021

The NF-kappa B and I kappa B proteins: new discoveries and insights

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7 January 2021

Regulation of inducible gene expression by the transcription factor NF-kappaB.

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7 January 2021

How NF-kappaB is activated: the role of the IkappaB kinase (IKK) complex

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7 January 2021

Negative regulation of nuclear factor-kappaB activation and function by glucocorticoids

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7 January 2021

Mechanism of suppression of cytochrome P-450 1A1 expression by tumor necrosis factor-alpha and lipopolysaccharide

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7 January 2021

Sulforaphane and its glutathione conjugate but not sulforaphane nitrile induce UDP-glucuronosyl transferase (UGT1A1) and glutathione transferase (GSTA1) in cultured cells.

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7 January 2021

Transcriptional control. Sinful repression

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7 January 2021

Transcriptional repression by UME6 involves deacetylation of lysine 5 of histone H4 by RPD3.

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7 January 2021

Rapid induction of NF-kappaB binding during liver cell isolation and culture: inhibition by L-NAME indicates a role for nitric oxide synthase.

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7 January 2021

Identification and analysis of drug-responsive expression of UDP-glucuronosyltransferase family 1 (UGT1) isozyme in rat hepatic microsomes using anti-peptide antibodies

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7 January 2021

Down-regulation of cytochrome P450 1A1 gene promoter by oxidative stress. Critical contribution of nuclear factor 1.

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7 January 2021

Suppression of CYP2C11 gene transcription by interleukin-1 mediated by NF-kappaB binding at the transcription start site

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7 January 2021

Down-regulation of human CYP3A4 by the inflammatory signal interleukin-6: molecular mechanism and transcription factors involved

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7 January 2021

Enhancement of glucuronide-conjugating capacity in a hyperbilirubinemic infant due to apparent enzyme induction by phenobarbital

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7 January 2021

Glucocorticoids repress NF-kappaB-driven genes by disturbing the interaction of p65 with the basal transcription machinery, irrespective of coactivator levels in the cell

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7 January 2021

Nuclear integration of glucocorticoid receptor and nuclear factor-kappaB signaling by CREB-binding protein and steroid receptor coactivator-1.

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7 January 2021

p65-activated histone acetyltransferase activity is repressed by glucocorticoids: mifepristone fails to recruit HDAC2 to the p65-HAT complex

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7 January 2021

Identifiers

DOI

10.1002/HEP.20387

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9 December 2017

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