(Q45099239)

9 December 2017

A 50-A separation of the integrin alpha v beta 3 extracellular domain C termini reveals an intermediate activation state (English)

1 reference

9 December 2017

Stephanie E Gline

1

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9 December 2017

Stephanie Cambier

series ordinal

2

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9 December 2017

Cedric Govaerts

series ordinal

3

1 reference

9 December 2017

Stephen L Nishimura

series ordinal

4

1 reference

9 December 2017

language of work or name

English

0 references

publication date

8 October 2004

1 reference

Journal of Biological Chemistry

9 December 2017

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9 December 2017

279

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9 December 2017

52

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9 December 2017

54567-54572

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Integrin structure: heady advances in ligand binding, but activation still makes the knees wobble

9 December 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406582200

A structural mechanism of integrin alpha(IIb)beta(3) "inside-out" activation as regulated by its cytoplasmic face

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406582200

Crystal structure of the extracellular segment of integrin alpha Vbeta3

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406582200

Crystal structure of the extracellular segment of integrin alpha Vbeta3 in complex with an Arg-Gly-Asp ligand

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406582200

Global conformational rearrangements in integrin extracellular domains in outside-in and inside-out signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406582200

Bidirectional transmembrane signaling by cytoplasmic domain separation in integrins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406582200

Breaking the integrin hinge. A defined structural constraint regulates integrin signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406582200

Stabilizing the open conformation of the integrin headpiece with a glycan wedge increases affinity for ligand

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406582200

Locking the beta3 integrin I-like domain into high and low affinity conformations with disulfides

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406582200

Reversibly locking a protein fold in an active conformation with a disulfide bond: integrin alphaL I domains with high affinity and antagonist activity in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406582200

Structure of integrin alpha5beta1 in complex with fibronectin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406582200

Structure of an integrin-ligand complex deduced from solution x-ray scattering and site-directed mutagenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406582200

The integrin alpha(v)beta8 mediates epithelial homeostasis through MT1-MMP-dependent activation of TGF-beta1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406582200

Crystal structure of alkaline phosphatase from human placenta at 1.8 A resolution. Implication for a substrate specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406582200

Transmembrane-truncated alphavbeta3 integrin retains high affinity for ligand binding: evidence for an 'inside-out' suppressor?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406582200

Topography of ligand-induced binding sites, including a novel cation-sensitive epitope (AP5) at the amino terminus, of the human integrin beta 3 subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406582200

Activation of integrin alphaIIbbeta3 by modulation of transmembrane helix associations

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406582200

21 January 2018

Identifiers

DOI

10.1074/JBC.M406582200

1 reference

9 December 2017

1 reference