(Q45128222)

9 December 2017

title

Tet oxidizes thymine to 5-hydroxymethyluracil in mouse embryonic stem cell DNA. (English)

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9 December 2017

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20

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9 December 2017

24

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9 December 2017

Markus Müller

23

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Fabio Spada

object named as

Fabio Spada

2

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Primo Schär

object named as

Primo Schär

22

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Stylianos Michalakis

12

object named as

Stylianos Michalakis

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9 December 2017

Toni Pfaffeneder

1

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9 December 2017

Mirko Wagner

3

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9 December 2017

Caterina Brandmayr

4

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9 December 2017

Silvia K Laube

5

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9 December 2017

David Eisen

6

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9 December 2017

Matthias Truss

7

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9 December 2017

Jessica Steinbacher

8

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9 December 2017

Benjamin Hackner

9

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9 December 2017

Olga Kotljarova

10

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9 December 2017

David Schuermann

11

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9 December 2017

Olesea Kosmatchev

13

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9 December 2017

Stefan Schiesser

14

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9 December 2017

Barbara Steigenberger

15

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9 December 2017

Nada Raddaoui

16

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9 December 2017

Gengo Kashiwazaki

17

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9 December 2017

Udo Müller

18

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9 December 2017

Cornelia G Spruijt

19

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9 December 2017

Heinrich Leonhardt

21

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9 December 2017

publication date

18 May 2014

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9 December 2017

published in

Nature Chemical Biology

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9 December 2017

volume

10

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9 December 2017

issue

7

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9 December 2017

page(s)

574-581

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DNA methylation: roles in mammalian development

9 December 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1532

5-Methylcytosine DNA demethylation: more than losing a methyl group

21 January 2018

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Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1

21 January 2018

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The discovery of 5-formylcytosine in embryonic stem cell DNA.

21 January 2018

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Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCHEMBIO.1532

Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNA

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCHEMBIO.1532

Tet family proteins and 5-hydroxymethylcytosine in development and disease

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCHEMBIO.1532

Thymine DNA glycosylase can rapidly excise 5-formylcytosine and 5-carboxylcytosine: potential implications for active demethylation of CpG sites

21 January 2018

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Hydroxylation of 5-methylcytosine by TET1 promotes active DNA demethylation in the adult brain

21 January 2018

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Thymine DNA glycosylase is essential for active DNA demethylation by linked deamination-base excision repair

21 January 2018

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AID/APOBEC deaminases disfavor modified cytosines implicated in DNA demethylation.

21 January 2018

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AID enzymatic activity is inversely proportional to the size of cytosine C5 orbital cloud

21 January 2018

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DNA glycosylases: in DNA repair and beyond

21 January 2018

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DNA glycosylase activities for thymine residues oxidized in the methyl group are functions of the hNEIL1 and hNTH1 enzymes in human cells

21 January 2018

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Quantification of DNA damage products resulting from deamination, oxidation and reaction with products of lipid peroxidation by liquid chromatography isotope dilution tandem mass spectrometry

21 January 2018

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Tissue distribution of 5-hydroxymethylcytosine and search for active demethylation intermediates

21 January 2018

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The nuclear DNA base 5-hydroxymethylcytosine is present in Purkinje neurons and the brain

21 January 2018

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Quantification of the sixth DNA base hydroxymethylcytosine in the brain

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCHEMBIO.1532

Quantitative assessment of Tet-induced oxidation products of 5-methylcytosine in cellular and tissue DNA.

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCHEMBIO.1532

FGF signaling inhibition in ESCs drives rapid genome-wide demethylation to the epigenetic ground state of pluripotency

21 January 2018

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Whole-genome bisulfite sequencing of two distinct interconvertible DNA methylomes of mouse embryonic stem cells

21 January 2018

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Naive pluripotency is associated with global DNA hypomethylation

21 January 2018

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Reconstitution of the mouse germ cell specification pathway in culture by pluripotent stem cells

21 January 2018

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Conversion of embryonic stem cells into neuroectodermal precursors in adherent monoculture

21 January 2018

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A screen for hydroxymethylcytosine and formylcytosine binding proteins suggests functions in transcription and chromatin regulation

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCHEMBIO.1532

Dynamic readers for 5-(hydroxy)methylcytosine and its oxidized derivatives

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1532

Directed DNA metallization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1532

A stepwise huisgen cycloaddition process: copper(I)-catalyzed regioselective "ligation" of azides and terminal alkynes

21 January 2018

1 reference

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Tandem Mass Tags: A Novel Quantification Strategy for Comparative Analysis of Complex Protein Mixtures by MS/MS

21 January 2018

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Quantitative analysis of complex protein mixtures using isotope-coded affinity tags

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1532

Recognition of 5-hydroxymethylcytosine by the Uhrf1 SRA domain

21 January 2018

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Cooperative DNA and histone binding by Uhrf2 links the two major repressive epigenetic pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1532

Definitive identification of mammalian 5-hydroxymethyluracil DNA N-glycosylase activity as SMUG1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1532

Uracil in DNA--general mutagen, but normal intermediate in acquired immunity

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCHEMBIO.1532

Active demethylation in mouse zygotes involves cytosine deamination and base excision repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1532

21 January 2018

Capturing pluripotency

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1532

DNA modifications repaired by base excision repair are epigenetic.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1532

Deamination, oxidation, and C-C bond cleavage reactivity of 5-hydroxymethylcytosine, 5-formylcytosine, and 5-carboxycytosine

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1532

Click Chemistry as a Reliable Method for the High-Density Postsynthetic Functionalization of Alkyne-Modified DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1532

Collisionally activated dissociation of protonated 2'-deoxycytidine, 2'-deoxyuridine, and their oxidatively damaged derivatives

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1532

Quantification of oxidative DNA lesions in tissues of Long-Evans Cinnamon rats by capillary high-performance liquid chromatography-tandem mass spectrometry coupled with stable isotope-dilution method

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1532

Establishment and maintenance of genomic methylation patterns in mouse embryonic stem cells by Dnmt3a and Dnmt3b.

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCHEMBIO.1532

Embryonic lethal phenotype reveals a function of TDG in maintaining epigenetic stability

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCHEMBIO.1532

Derivation of completely cell culture-derived mice from early-passage embryonic stem cells

21 January 2018

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Somatic mutations in the neurofibromatosis 1 gene in human tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1532

Kindlin-2 controls bidirectional signaling of integrins

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCHEMBIO.1532

Defined conditions for neural commitment and differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1532

TET1 and hydroxymethylcytosine in transcription and DNA methylation fidelity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1532

Production of endoribonuclease-prepared short interfering RNAs for gene silencing in mammalian cells

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCHEMBIO.1532

Base-resolution analysis of 5-hydroxymethylcytosine in the mammalian genome.

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCHEMBIO.1532

Ionic and radical oxidations of DNA by hydrogen peroxide

21 January 2018

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12 December 2020

Surviving an Oxygen Atmosphere: DNA Damage and Repair

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12 December 2020

Serologic Assay of DNA Base Damage: I. 5-Hydroxymethyldeoxyuridine, A Radiation Product of Thymidine

1 reference

12 December 2020

Targeted mutation of the DNA methyltransferase gene results in embryonic lethality

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12 December 2020

Oxidation of thymine to 5-formyluracil in DNA: mechanisms of formation, structural implications, and base excision by human cell free extracts

1 reference

12 December 2020

Identifiers

DOI

10.1038/NCHEMBIO.1532

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Dimensions Publication ID

9 December 2017

1038572510

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