(Q45144504)

English

Kinetics of nucleotide incorporation opposite DNA bulky guanine N2 adducts by processive bacteriophage T7 DNA polymerase (exonuclease-) and HIV-1 reverse transcriptase

scientific article published on 8 November 2004

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scholarly article

1 reference

Europe PubMed Central

10 December 2017

Kinetics of nucleotide incorporation opposite DNA bulky guanine N2 adducts by processive bacteriophage T7 DNA polymerase (exonuclease-) and HIV-1 reverse transcriptase (English)

1 reference

Europe PubMed Central

10 December 2017

1 reference

based on heuristic

inferred from title

F. Peter Guengerich

3

object named as

F Peter Guengerich

1 reference

Europe PubMed Central

10 December 2017

author name string

Hong Zang

1

1 reference

Europe PubMed Central

10 December 2017

Thomas M Harris

2

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Europe PubMed Central

10 December 2017

language of work or name

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publication date

8 November 2004

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Europe PubMed Central

10 December 2017

Journal of Biological Chemistry

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Europe PubMed Central

10 December 2017

280

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Europe PubMed Central

10 December 2017

2

1 reference

Europe PubMed Central

10 December 2017

1165-1178

1 reference

Europe PubMed Central

10 December 2017

Fidelity mechanisms in DNA replication

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Biochemical basis of DNA replication fidelity

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DNA replication fidelity

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Eukaryotic DNA polymerases: proposal for a revised nomenclature.

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Conformational coupling in DNA polymerase fidelity

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An induced-fit kinetic mechanism for DNA replication fidelity: direct measurement by single-turnover kinetics

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Analysis of nucleotide insertion and extension at 8-oxo-7,8-dihydroguanine by replicative T7 polymerase exo- and human immunodeficiency virus-1 reverse transcriptase using steady-state and pre-steady-state kinetics

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Explanation of pre-steady-state kinetics and decreased burst amplitude of HIV-1 reverse transcriptase at sites of modified DNA bases with an additional, nonproductive enzyme-DNA-nucleotide complex

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21 January 2018

Fidelity of nucleotide insertion at 8-oxo-7,8-dihydroguanine by mammalian DNA polymerase delta. Steady-state and pre-steady-state kinetic analysis

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21 January 2018

Effect of the O6 substituent on misincorporation kinetics catalyzed by DNA polymerases at O(6)-methylguanine and O(6)-benzylguanine

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Misincorporation and stalling at O(6)-methylguanine and O(6)-benzylguanine: evidence for inactive polymerase complexes

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Analysis of the effect of bulk at N2-alkylguanine DNA adducts on catalytic efficiency and fidelity of the processive DNA polymerases bacteriophage T7 exonuclease- and HIV-1 reverse transcriptase

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Rate-limiting steps in the DNA polymerase I reaction pathway

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Kinetic mechanism of DNA polymerase I (Klenow).

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1,3-Butadiene: exposure estimation, hazard characterization, and exposure-response analysis

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Genotoxic properties of 1,3-butadiene

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Synthesis, characterization, and in vitro quantitation of N-7-guanine adducts of diepoxybutane

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Adenine adducts with diepoxybutane: isolation and analysis in exposed calf thymus DNA.

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Characterization of four N-3-thymidine adducts formed in vitro by the reaction of thymidine and butadiene monoxide.

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Translesion DNA synthesis by yeast DNA polymerase eta on templates containing N2-guanine adducts of 1,3-butadiene metabolites

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Endogenous formation and significance of 1,N2-propanodeoxyguanosine adducts

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Mammalian translesion DNA synthesis across an acrolein-derived deoxyguanosine adduct. Participation of DNA polymerase eta in error-prone synthesis in human cells

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The genetic toxicology of styrene and styrene oxide.

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Styrene oxide adducts in an oligodeoxynucleotide containing the human N-ras codon 12: minor groove structures of the R(12,1)- and S(12,1)-alpha-(N2-guanyl) stereoisomers determined by 1H nuclear magnetic resonance

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Synthesis and characterization of nucleosides and oligonucleotides bearing adducts of butadiene epoxides on adenine n(6) and guanine n(2).

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21 January 2018

Stereospecific synthesis of oligonucleotides containing crotonaldehyde adducts of deoxyguanosine

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21 January 2018

Evaluation of the mutagenic potential of the principal DNA adduct of acrolein

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21 January 2018

Error prone translesion synthesis past gamma-hydroxypropano deoxyguanosine, the primary acrolein-derived adduct in mammalian cells

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21 January 2018

DNA adducts of acrolein: site-specific synthesis of an oligodeoxynucleotide containing 6-hydroxy-5,6,7,8-tetrahydropyrimido[1,2-a]purin-10(3H)-one, an acrolein adduct of guanine

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Improved strategies for postoligomerization synthesis of oligodeoxynucleotides bearing structurally defined adducts at the N2 position of deoxyguanosine.

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21 January 2018

Pre-steady-state kinetic analysis of processive DNA replication including complete characterization of an exonuclease-deficient mutant

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21 January 2018

Insights into DNA polymerization mechanisms from structure and function analysis of HIV-1 reverse transcriptase

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21 January 2018

Steady-state and pre-steady-state kinetic analysis of 8-oxo-7,8-dihydroguanosine triphosphate incorporation and extension by replicative and repair DNA polymerases

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21 January 2018

Rate-determining steps in phenacetin oxidations by human cytochrome P450 1A2 and selected mutants

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DNA secondary structure effects on DNA synthesis catalyzed by HIV-1 reverse transcriptase

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21 January 2018

Kinetic partitioning between the exonuclease and polymerase sites in DNA error correction

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Mutants affecting nucleotide recognition by T7 DNA polymerase.

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Crystal structure of human immunodeficiency virus type 1 reverse transcriptase complexed with double-stranded DNA at 3.0 A resolution shows bent DNA

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Role of the C-terminal residue of the DNA polymerase of bacteriophage T7.

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Crystal structure of a bacteriophage T7 DNA replication complex at 2.2 A resolution

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Structure of a covalently trapped catalytic complex of HIV-1 reverse transcriptase: implications for drug resistance

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Use of single-turnover kinetics to study bulky adduct bypass by T7 DNA polymerase

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Single d(GpG)/cis-diammineplatinum(II) adduct-induced inhibition of DNA polymerization

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Effects of benzo[a]pyrene DNA adducts on Escherichia coli DNA polymerase I (Klenow fragment) primer-template interactions: evidence for inhibition of the catalytically active ternary complex formation.

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Translesion synthesis past acrolein-derived DNA adduct, gamma -hydroxypropanodeoxyguanosine, by yeast and human DNA polymerase eta.

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21 January 2018

Comparative evaluation of the bioreactivity and mutagenic spectra of acrolein-derived alpha-HOPdG and gamma-HOPdG regioisomeric deoxyguanosine adducts

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NMR characterization of a DNA duplex containing the major acrolein-derived deoxyguanosine adduct gamma -OH-1,-N2-propano-2'-deoxyguanosine

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Detection of an interchain carbinolamine cross-link formed in a CpG sequence by the acrolein DNA adduct gamma-OH-1,N( 2)-propano-2'-deoxyguanosine

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Mutagenesis by acrolein-derived propanodeoxyguanosine adducts in human cells

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Base sequence dependence of in vitro translesional DNA replication past a bulky lesion catalyzed by the exo- Klenow fragment of Pol I.

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Translesion synthesis by human DNA polymerase kappa on a DNA template containing a single stereoisomer of dG-(+)- or dG-(-)-anti-N(2)-BPDE (7,8-dihydroxy-anti-9,10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene).

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Translesional synthesis on DNA templates containing a single abasic site. A mechanistic study of the "A rule".

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Mechanism of DNA replication fidelity for three mutants of DNA polymerase I: Klenow fragment KF(exo+), KF(polA5), and KF(exo-).

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Minimal kinetic mechanism for misincorporation by DNA polymerase I (Klenow fragment)

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Steady-state and pre-steady-state kinetic analysis of dNTP insertion opposite 8-oxo-7,8-dihydroguanine by Escherichia coli polymerases I exo- and II exo-.

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Effect of RNA secondary structure on the kinetics of DNA synthesis catalyzed by HIV-1 reverse transcriptase

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Kinetic analysis of nucleotide incorporation by mammalian DNA polymerase delta

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Efficiency and accuracy of SOS-induced DNA polymerases replicating benzo[a]pyrene-7,8-diol 9,10-epoxide A and G adducts

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21 January 2018

trans-Lesion synthesis past bulky benzo[a]pyrene diol epoxide N2-dG and N6-dA lesions catalyzed by DNA bypass polymerases

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Effects of base sequence context on translesion synthesis past a bulky (+)-trans-anti-B[a]P-N2-dG lesion catalyzed by the Y-family polymerase pol kappa.

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21 January 2018

Preferential misincorporation of purine nucleotides by human DNA polymerase eta opposite benzo[a]pyrene 7,8-diol 9,10-epoxide deoxyguanosine adducts

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21 January 2018

Two-step error-prone bypass of the (+)- and (-)-trans-anti-BPDE-N2-dG adducts by human DNA polymerases eta and kappa

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21 January 2018

Translesion replication of benzo[a]pyrene and benzo[c]phenanthrene diol epoxide adducts of deoxyadenosine and deoxyguanosine by human DNA polymerase iota

1 reference

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21 January 2018

Benzo[a]pyrene diol epoxide-deoxyguanosine adducts are accurately bypassed by yeast DNA polymerase zeta in vitro

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21 January 2018

Identifiers

10.1074/JBC.M405996200

1 reference

Europe PubMed Central

10 December 2017

1 reference

Europe PubMed Central

10 December 2017

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