(Q45154618)

10 December 2017

title

Site-specific disulfide capture of agonist and antagonist peptides on the C5a receptor (English)

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10 December 2017

Elizabeth Buck

1

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10 December 2017

Henry Bourne

series ordinal

2

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10 December 2017

James A Wells

series ordinal

3

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10 December 2017

language of work or name

English

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publication date

18 November 2004

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Journal of Biological Chemistry

10 December 2017

published in

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10 December 2017

volume

280

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10 December 2017

issue

6

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10 December 2017

page(s)

4009-4012

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Molecular tinkering of G protein-coupled receptors: an evolutionary success

10 December 2017

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Site-specific mutagenesis of residues in the human C5a anaphylatoxin which are involved in possible interaction with the C5a receptor

21 January 2018

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Mapping the ligand-binding site on the C5a receptor: arginine74 of C5a contacts aspartate282 of the C5a receptor

21 January 2018

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Residues 21-30 within the extracellular N-terminal region of the C5a receptor represent a binding domain for the C5a anaphylatoxin

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An activation switch in the ligand binding pocket of the C5a receptor

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Characteristics for a salt-bridge switch mutation of the alpha(1b) adrenergic receptor. Altered pharmacology and rescue of constitutive activity

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Impaired inflammatory responses in the reverse arthus reaction through genetic deletion of the C5a receptor

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21 January 2018

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Probing the "message:address" sites for chemoattractant binding to the C5a receptor. Mutagenesis of hydrophilic and proline residues within the transmembrane segments

21 January 2018

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Two-site binding of C5a by its receptor: an alternative binding paradigm for G protein-coupled receptors

21 January 2018

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Low-molecular-weight peptidic and cyclic antagonists of the receptor for the complement factor C5a.

21 January 2018

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21 January 2018

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Genetic mapping of the human C5a receptor. Identification of transmembrane amino acids critical for receptor function

21 January 2018

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Identification of receptor-binding residues in the inflammatory complement protein C5a by site-directed mutagenesis

21 January 2018

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Site-directed mutagenesis of conserved charged residues in the helical region of the human C5a receptor. Arg2O6 determines high-affinity binding sites of C5a receptor

21 January 2018

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Tethering: fragment-based drug discovery

21 January 2018

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Site-directed ligand discovery

21 January 2018

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Potent small-molecule binding to a dynamic hot spot on IL-2

21 January 2018

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Allosteric inhibition of protein tyrosine phosphatase 1B.

21 January 2018

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Conversion of agonist site to metal-ion chelator site in the beta(2)-adrenergic receptor

21 January 2018

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Molecular mechanism of agonism and inverse agonism in the melanocortin receptors: Zn(2+) as a structural and functional probe

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.C400500200

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10 December 2017

1 reference