(Q44982496)

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30 December 2019

title

Allosteric inhibition of protein tyrosine phosphatase 1B (English)

1 reference

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30 December 2019

1

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30 December 2019

7

Bruce J Fahr

1 reference

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30 December 2019

author name string

Kenneth J Barr

2

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30 December 2019

Jenny Kung

3

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30 December 2019

Jiang Zhu

4

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30 December 2019

Daniel A Erlanson

5

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30 December 2019

Wang Shen

6

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30 December 2019

Min Zhong

8

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30 December 2019

Lisa Taylor

9

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30 December 2019

Mike Randal

10

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30 December 2019

Robert S McDowell

11

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30 December 2019

Stig K Hansen

12

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30 December 2019

publication date

18 July 2004

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Nature Structural & Molecular Biology

30 December 2019

published in

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30 December 2019

volume

11

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30 December 2019

page(s)

730-737

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30 December 2019

issue

8

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https://scigraph.springernature.com/pub.10.1038/nsmb803

30 December 2019

exact match

0 references

cites work

New perspectives into the molecular pathogenesis and treatment of type 2 diabetes

1 reference

Osmotic loading of neutralizing antibodies demonstrates a role for protein-tyrosine phosphatase 1B in negative regulation of the insulin action pathway

21 January 2018

1 reference

Protein tyrosine phosphatase 1B interacts with the activated insulin receptor

21 January 2018

1 reference

Protein-tyrosine phosphatase 1B is a negative regulator of insulin- and insulin-like growth factor-I-stimulated signaling

21 January 2018

1 reference

Increased insulin sensitivity and obesity resistance in mice lacking the protein tyrosine phosphatase-1B gene

21 January 2018

1 reference

Increased energy expenditure, decreased adiposity, and tissue-specific insulin sensitivity in protein-tyrosine phosphatase 1B-deficient mice

21 January 2018

1 reference

Protein tyrosine phosphatase 1B reduction regulates adiposity and expression of genes involved in lipogenesis

21 January 2018

1 reference

PTP1B antisense oligonucleotide lowers PTP1B protein, normalizes blood glucose, and improves insulin sensitivity in diabetic mice

21 January 2018

1 reference

Protein tyrosine phosphatase 1B inhibitors for diabetes

21 January 2018

1 reference

PTP1B inhibition and antihyperglycemic activity in the ob/ob mouse model of novel 11-arylbenzo[b]naphtho[2,3-d]furans and 11-arylbenzo[b]naphtho[2,3-d]thiophenes

21 January 2018

1 reference

Crystal structure of human protein tyrosine phosphatase 1B

21 January 2018

1 reference

Structural basis for phosphotyrosine peptide recognition by protein tyrosine phosphatase 1B

21 January 2018

1 reference

Identification of a second aryl phosphate-binding site in protein-tyrosine phosphatase 1B: a paradigm for inhibitor design

21 January 2018

1 reference

Structure-based design of a low molecular weight, nonphosphorus, nonpeptide, and highly selective inhibitor of protein-tyrosine phosphatase 1B

21 January 2018

1 reference

Visualization of the cysteinyl-phosphate intermediate of a protein-tyrosine phosphatase by x-ray crystallography

21 January 2018

1 reference

Visualization of intermediate and transition-state structures in protein-tyrosine phosphatase catalysis

21 January 2018

1 reference

Small molecule peptidomimetics containing a novel phosphotyrosine bioisostere inhibit protein tyrosine phosphatase 1B and augment insulin action

21 January 2018

1 reference

Cellular effects of small molecule PTP1B inhibitors on insulin signaling

21 January 2018

1 reference

Molecular basis for the dephosphorylation of the activation segment of the insulin receptor by protein tyrosine phosphatase 1B

21 January 2018

1 reference

Can allosteric regulation be predicted from structure?

21 January 2018

1 reference

Structural and evolutionary relationships among protein tyrosine phosphatase domains

21 January 2018

1 reference

Crystal structure of the tandem phosphatase domains of RPTP LAR

21 January 2018

1 reference

Direct binding of the proline-rich region of protein tyrosine phosphatase 1B to the Src homology 3 domain of p130(Cas)

21 January 2018

1 reference

Implications of protein flexibility for drug discovery

21 January 2018

1 reference

Allosteric binding sites on cell-surface receptors: novel targets for drug discovery

21 January 2018

1 reference

Structural mechanism for STI-571 inhibition of abelson tyrosine kinase

21 January 2018

1 reference

Inhibition of p38 MAP kinase by utilizing a novel allosteric binding site

21 January 2018

1 reference

Discovery of a New Phosphotyrosine Mimetic for PTP1B Using Breakaway Tethering

21 January 2018

1 reference

2-(oxalylamino)-benzoic acid is a general, competitive inhibitor of protein-tyrosine phosphatases

21 January 2018

1 reference

The finer things in X-ray diffraction data collection

21 January 2018

1 reference

The CCP4 suite: programs for protein crystallography

21 January 2018

1 reference

Improved methods for building protein models in electron density maps and the location of errors in these models

21 January 2018

1 reference

Down-regulation of Insulin Signaling by Protein-tyrosine Phosphatase 1B Is Mediated by an N-terminal Binding Region

21 January 2018

1 reference

The Noncatalytic C-terminal Segment of the T Cell Protein Tyrosine Phosphatase Regulates Activity via an Intramolecular Mechanism

21 January 2018

1 reference

Protein-tyrosine phosphatases PTP1B and syp are modulators of insulin-stimulated translocation of GLUT4 in transfected rat adipose cells

21 January 2018

1 reference

31 March 2020

Identifiers

DOI

10.1038/NSMB803

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15258570%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

1 reference