(Q45183033)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15591471%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

title

A role for hydroxy-methylglutaryl coenzyme a reductase in pulmonary inflammation and host defense (English)

1 reference

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6 January 2020

1

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6 January 2020

author name string

Scott K Young

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15591471%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

Samithamby Jeyaseelan

3

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15591471%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

Jonathan G Lieber

4

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6 January 2020

Patrick G Arndt

5

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6 January 2020

Jerry A Nick

6

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6 January 2020

G Scott Worthen

7

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6 January 2020

language of work or name

English

0 references

publication date

10 December 2004

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15591471%20AND%20SRC:MED&resulttype=core&format=json

American Journal of Respiratory and Critical Care Medicine

6 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15591471%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

volume

171

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6 January 2020

issue

6

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6 January 2020

page(s)

606-615

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15591471%20AND%20SRC:MED&resulttype=core&format=json

Cerivastatin ameliorates high insulin-enhanced neutrophil–endothelial cell adhesion and endothelial intercellular adhesion molecule-1 expression by inhibiting mitogen-activated protein kinase activation

6 January 2020

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Simvastatin suppresses LPS-induced Akt phosphorylation in the human monocyte cell line THP-1.

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Mevastatin suppresses lipopolysaccharide-induced Rac activation in the human monocyte cell line THP-1.

21 January 2018

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Simvastatin attenuates leucocyte-endothelial interactions after coronary revascularisation with cardiopulmonary bypass

21 January 2018

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Statins selectively inhibit leukocyte function antigen-1 by binding to a novel regulatory integrin site

21 January 2018

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Isoprenoid metabolism and the pleiotropic effects of statins

21 January 2018

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A new HMG-CoA reductase inhibitor, rosuvastatin, exerts anti-inflammatory effects on the microvascular endothelium: the role of mevalonic acid

21 January 2018

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Cytoskeletal activation and altered gene expression in endothelial barrier regulation by simvastatin

21 January 2018

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In vivo anti-inflammatory effect of statins is mediated by nonsterol mevalonate products

21 January 2018

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Fluvastatin treatment inhibits leucocyte adhesion and extravasation in models of complement-mediated acute inflammation.

21 January 2018

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Simvastatin ameliorates injury in an experimental model of lung ischemia-reperfusion

21 January 2018

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The effect of statins on mortality in patients with bacteremia

21 January 2018

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Sleep apnea and markers of vascular endothelial function in a large community sample of older adults.

21 January 2018

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Selective suppression of neutrophil accumulation in ongoing pulmonary inflammation by systemic inhibition of p38 mitogen-activated protein kinase

21 January 2018

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Selective activation and functional significance of p38alpha mitogen-activated protein kinase in lipopolysaccharide-stimulated neutrophils

21 January 2018

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The in vitro production and characterization of neutrophils from embryonic stem cells

21 January 2018

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Neutrophil activation and acute lung injury.

21 January 2018

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Neutrophils and acute lung injury

21 January 2018

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A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

21 January 2018

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Protective effects of sphingosine 1-phosphate in murine endotoxin-induced inflammatory lung injury

21 January 2018

1 reference

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Hydroxymethylglutaryl coenzyme A reductase inhibitors modify the inflammatory response of human macrophages and endothelial cells infected with Chlamydia pneumoniae

21 January 2018

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Role of inflammatory mediators in the pathophysiology of acute respiratory distress syndrome

21 January 2018

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Cell migration: integrating signals from front to back

21 January 2018

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Chemoattractant-stimulated Rac activation in wild-type and Rac2-deficient murine neutrophils: preferential activation of Rac2 and Rac2 gene dosage effect on neutrophil functions

21 January 2018

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Regulation of intracellular actin polymerization by prenylated cellular proteins

21 January 2018

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Interaction of Klebsiella capsule type 7 with human polymorphonuclear leucocytes

21 January 2018

1 reference

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Withdrawal of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors elicits oxidative stress and induces endothelial dysfunction in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.200406-729OC

Statin inhibition of Fc receptor-mediated phagocytosis by macrophages is modulated by cell activation and cholesterol

21 January 2018

1 reference

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Mouse Lysozyme M Is Important in Pulmonary Host Defense againstKlebsiella pneumoniaeInfection

21 January 2018

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Impairment of respiratory burst in polymorphonuclear leukocytes by extended-spectrum beta-lactamase-producing strains of Klebsiella pneumoniae.

21 January 2018

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Variants of toll-like receptor 4 modify the efficacy of statin therapy and the risk of cardiovascular events

21 January 2018

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Crosstalk between LXR and Toll-like Receptor Signaling Mediates Bacterial and Viral Antagonism of Cholesterol Metabolism

21 January 2018

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Lipopolysaccharide down regulates both scavenger receptor B1 and ATP binding cassette transporter A1 in RAW cells

21 January 2018

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Human lipoproteins have divergent neutralizing effects on E. coli LPS, N. meningitidis LPS, and complete Gram-negative bacteria

21 January 2018

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Binding and internalization of lipopolysaccharide by Cla-1, a human orthologue of rodent scavenger receptor B1

21 January 2018

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Hmg-CoA reductase inhibitor modulates monocyte-endothelial cell interaction under physiological flow conditions in vitro: involvement of Rho GTPase-dependent mechanism

21 January 2018

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Simvastatin augments lipopolysaccharide-induced proinflammatory responses in macrophages by differential regulation of the c-Fos and c-Jun transcription factors

21 January 2018

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Cholesterol depletion from the plasma membrane triggers ligand-independent activation of the epidermal growth factor receptor

21 January 2018

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Lipid rafts regulate lipopolysaccharide-induced activation of Cdc42 and inflammatory functions of the human neutrophil

21 January 2018

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Polarized distribution of endogenous Rac1 and RhoA at the cell surface

21 January 2018

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Mechanism of NADPH oxidase activation by the Rac/Rho-GDI complex

21 January 2018

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Requirement for posttranslational processing of Rac GTP-binding proteins for activation of human neutrophil NADPH oxidase

21 January 2018

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NAD(P)H oxidase-derived superoxide mediates hypercholesterolemia-induced leukocyte-endothelial cell adhesion

21 January 2018

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The impact of intravenous fat emulsion administration in acute lung injury

21 January 2018

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Sphingosine 1-phosphate reduces vascular leak in murine and canine models of acute lung injury

21 January 2018

1 reference

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10.1164/RCCM.200406-729OC

21 January 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15591471%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

1 reference