(Q45183730)

English

Common polymorphisms of the PPAR-gamma2 (Pro12Ala) and PGC-1alpha (Gly482Ser) genes are associated with the conversion from impaired glucose tolerance to type 2 diabetes in the STOP-NIDDM trial

scientific article published on 8 December 2004

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

10 December 2017

Common polymorphisms of the PPAR-gamma2 (Pro12Ala) and PGC-1alpha (Gly482Ser) genes are associated with the conversion from impaired glucose tolerance to type 2 diabetes in the STOP-NIDDM trial (English)

1 reference

Europe PubMed Central

PubMed publication ID

10 December 2017

type 2 diabetes

1 reference

based on heuristic

inferred from title

4

object named as

M Laakso

1 reference

Europe PubMed Central

PubMed publication ID

10 December 2017

author name string

L Andrulionytè

1

1 reference

Europe PubMed Central

PubMed publication ID

10 December 2017

J Zacharova

2

1 reference

Europe PubMed Central

PubMed publication ID

10 December 2017

J-L Chiasson

3

1 reference

Europe PubMed Central

PubMed publication ID

10 December 2017

STOP-NIDDM Study Group

5

1 reference

Europe PubMed Central

PubMed publication ID

10 December 2017

publication date

8 December 2004

1 reference

Europe PubMed Central

PubMed publication ID

10 December 2017

1 reference

Europe PubMed Central

PubMed publication ID

10 December 2017

47

1 reference

Europe PubMed Central

PubMed publication ID

10 December 2017

12

1 reference

Europe PubMed Central

PubMed publication ID

10 December 2017

2176-2184

1 reference

Europe PubMed Central

PubMed publication ID

10 December 2017

https://scigraph.springernature.com/pub.10.1007/s00125-004-1577-2

0 references

Prospective study of the association between the proline to alanine codon 12 polymorphism in the PPARgamma gene and type 2 diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/15592662

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Assessment of insulin sensitivity and beta-cell function from measurements in the fasting state and during an oral glucose tolerance test.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15592662

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The peroxisome proliferator-activated receptor-gamma2 Pro12A1a variant: association with type 2 diabetes and trait differences.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15592662

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin sensitivity and insulin secretion in monozygotic and dizygotic twins.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15592662

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impact of the Peroxisome Proliferator Activated Receptor γ2 Pro12Ala polymorphism on adiposity, lipids and non-insulin-dependent diabetes mellitus

1 reference

https://pubmed.ncbi.nlm.nih.gov/15592662

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The inherited basis of diabetes mellitus: implications for the genetic analysis of complex traits

1 reference

https://pubmed.ncbi.nlm.nih.gov/15592662

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A Gly482Ser missense mutation in the peroxisome proliferator-activated receptor gamma coactivator-1 is associated with altered lipid oxidation and early insulin secretion in Pima Indians

1 reference

https://pubmed.ncbi.nlm.nih.gov/15592662

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stimulation of adipogenesis in fibroblasts by PPAR gamma 2, a lipid-activated transcription factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/15592662

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A genetic variation in the PGC-1 gene could confer insulin resistance and susceptibility to Type II diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/15592662

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acarbose for prevention of type 2 diabetes mellitus: the STOP-NIDDM randomised trial

1 reference

https://pubmed.ncbi.nlm.nih.gov/15592662

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PPARgamma, the ultimate thrifty gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/15592662

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peroxisome proliferator-activated receptor gamma 2 Pro12Ala gene variant is strongly associated with larger body mass in the Taiwanese.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15592662

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A Pro12Ala substitution in PPARgamma2 associated with decreased receptor activity, lower body mass index and improved insulin sensitivity

1 reference

https://pubmed.ncbi.nlm.nih.gov/15592662

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1

1 reference

https://pubmed.ncbi.nlm.nih.gov/15592662

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association of the Pro12Ala polymorphism in the PPAR-gamma2 gene with 3-year incidence of type 2 diabetes and body weight change in the Finnish Diabetes Prevention Study

1 reference

https://pubmed.ncbi.nlm.nih.gov/15592662

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

No association between the G482S polymorphism of the proliferator-activated receptor-gamma coactivator-1 (PGC-1) gene and Type II diabetes in French Caucasians

1 reference

https://pubmed.ncbi.nlm.nih.gov/15592662

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transcriptional co-activator PGC-1 alpha drives the formation of slow-twitch muscle fibres

1 reference

https://pubmed.ncbi.nlm.nih.gov/15592662

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Significance of Pro12Ala mutation in peroxisome proliferator-activated receptor-gamma2 in Korean diabetic and obese subjects

1 reference

https://pubmed.ncbi.nlm.nih.gov/15592662

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PPARgamma : a nuclear regulator of metabolism, differentiation, and cell growth

1 reference

https://pubmed.ncbi.nlm.nih.gov/15592662

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15592662

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/15592662

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pro12Ala substitution in the peroxisome proliferator-activated receptor-gamma2 is not associated with type 2 diabetes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15592662

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutation analysis of peroxisome proliferator-activated receptor-gamma coactivator-1 (PGC-1) and relationships of identified amino acid polymorphisms to Type II diabetes mellitus

1 reference

https://pubmed.ncbi.nlm.nih.gov/15592662

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PGC-1alpha at the crossroads of type 2 diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/15592662

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peroxisome proliferator-activated receptor-gamma coactivator 1 alpha (PGC-1 alpha): transcriptional coactivator and metabolic regulator

1 reference

https://pubmed.ncbi.nlm.nih.gov/15592662

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Concordance rate for type II diabetes mellitus in monozygotic twins: actuarial analysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15592662

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An autosomal genomic scan for loci linked to prediabetic phenotypes in Pima Indians

1 reference

https://pubmed.ncbi.nlm.nih.gov/15592662

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pro12Ala missense mutation of the peroxisome proliferator activated receptor gamma and diabetes mellitus

1 reference

https://pubmed.ncbi.nlm.nih.gov/15592662

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduced expression of PGC-1 and insulin-signaling molecules in adipose tissue is associated with insulin resistance

1 reference

https://pubmed.ncbi.nlm.nih.gov/15592662

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human peroxisome proliferator activated receptor gamma coactivator 1 (PPARGC1) gene: cDNA sequence, genomic organization, chromosomal localization, and tissue expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/15592662

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Pro12Ala polymorphism in PPAR gamma2 may confer resistance to type 2 diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/15592662

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased prevalence of left ventricular hypertrophy in hypertensive women with type 2 diabetes mellitus

1 reference

https://pubmed.ncbi.nlm.nih.gov/15592662

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transcriptional regulation of adipogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15592662

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

mPPAR gamma 2: tissue-specific regulator of an adipocyte enhancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/15592662

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The STOP-NIDDM Trial: an international study on the efficacy of an alpha-glucosidase inhibitor to prevent type 2 diabetes in a population with impaired glucose tolerance: rationale, design, and preliminary screening data. Study to Prevent Non-Insuli

1 reference

https://pubmed.ncbi.nlm.nih.gov/15592662

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Pro115Gln and Pro12Ala PPAR gamma gene mutations in obesity and type 2 diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/15592662

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetics of non-insulin-dependent (type-II) diabetes mellitus

1 reference

https://pubmed.ncbi.nlm.nih.gov/15592662

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The mechanisms by which both heterozygous peroxisome proliferator-activated receptor gamma (PPARgamma) deficiency and PPARgamma agonist improve insulin resistance

1 reference

https://pubmed.ncbi.nlm.nih.gov/15592662

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The common PPARgamma Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/15592662

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Pro12 -->Ala substitution in PPAR-gamma is associated with resistance to development of diabetes in the general population: possible involvement in impairment of insulin secretion in individuals with type 2 diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/15592662

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PPAR gamma mediates high-fat diet-induced adipocyte hypertrophy and insulin resistance

1 reference

https://pubmed.ncbi.nlm.nih.gov/15592662

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PPAR(gamma) and glucose homeostasis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15592662

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor gamma (PPAR gamma)

1 reference

https://pubmed.ncbi.nlm.nih.gov/15592662

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PPAR-gamma: adipogenic regulator and thiazolidinedione receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/15592662

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The metabolic syndrome: peroxisome proliferator-activated receptor gamma and its therapeutic modulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/15592662

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Coordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes: Potential role of PGC1 and NRF1

1 reference

https://pubmed.ncbi.nlm.nih.gov/15592662

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of experimental elevation of free fatty acids on insulin secretion and insulin sensitivity in healthy carriers of the Pro12Ala polymorphism of the peroxisome proliferator--activated receptor-gamma2 gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/15592662

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Restoration of insulin-sensitive glucose transporter (GLUT4) gene expression in muscle cells by the transcriptional coactivator PGC-1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15592662

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular scanning of the human peroxisome proliferator activated receptor gamma (hPPAR gamma) gene in diabetic Caucasians: identification of a Pro12Ala PPAR gamma 2 missense mutation

1 reference

https://pubmed.ncbi.nlm.nih.gov/15592662

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S00125-004-1577-2

1 reference

Europe PubMed Central

PubMed publication ID

10 December 2017

Dimensions Publication ID

0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

10 December 2017

ResearchGate publication ID

0 references

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