(Q45230466)

English

Antiproliferative plant and synthetic polyphenolics are specific inhibitors of vertebrate inositol-1,4,5-trisphosphate 3-kinases and inositol polyphosphate multikinase

scientific article published on 19 January 2005

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scholarly article

1 reference

Europe PubMed Central

11 December 2017

Antiproliferative plant and synthetic polyphenolics are specific inhibitors of vertebrate inositol-1,4,5-trisphosphate 3-kinases and inositol polyphosphate multikinase (English)

1 reference

Europe PubMed Central

11 December 2017

1 reference

ChEBI release 2020-05-28

author name string

Georg W Mayr

1

1 reference

Europe PubMed Central

11 December 2017

Sabine Windhorst

2

1 reference

Europe PubMed Central

11 December 2017

Kirsten Hillemeier

3

1 reference

Europe PubMed Central

11 December 2017

language of work or name

0 references

publication date

19 January 2005

1 reference

Europe PubMed Central

11 December 2017

Journal of Biological Chemistry

1 reference

Europe PubMed Central

11 December 2017

280

1 reference

Europe PubMed Central

11 December 2017

14

1 reference

Europe PubMed Central

11 December 2017

13229-13240

1 reference

Europe PubMed Central

11 December 2017

The inositol tris/tetrakisphosphate pathway--demonstration of Ins(1,4,5)P3 3-kinase activity in animal tissues

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500545200

21 January 2018

Purification of bovine brain inositol 1,4,5-trisphosphate 3-kinase. Identification of the enzyme by sodium dodecyl sulphate/polyacrylamide-gel electrophoresis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500545200

21 January 2018

Cloning and expression in Escherichia coli of a rat brain cDNA encoding a Ca2+/calmodulin-sensitive inositol 1,4,5-trisphosphate 3-kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500545200

21 January 2018

Molecular cloning and expression of a human brain inositol 1,4,5-trisphosphate 3-kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500545200

21 January 2018

Cloning and expression of a full-length cDNA encoding human inositol 1,4,5-trisphosphate 3-kinase B.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500545200

21 January 2018

Cloning and expression of a cDNA encoding human inositol 1,4,5-trisphosphate 3-kinase C.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500545200

21 January 2018

The families of kinases removing the Ca2+ releasing second messenger Ins(1,4,5)P3.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500545200

21 January 2018

Identification of the actin-binding domain of Ins(1,4,5)P3 3-kinase isoform B (IP3K-B).

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500545200

21 January 2018

The three isoenzymes of human inositol-1,4,5-trisphosphate 3-kinase show specific intracellular localization but comparable Ca2+ responses on transfection in COS-7 cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500545200

21 January 2018

Membrane association, localization and topology of rat inositol 1,4,5-trisphosphate 3-kinase B: implications for membrane traffic and Ca2+ homoeostasis.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500545200

21 January 2018

Tissue- and cell-specific expression of Ins(1,4,5)P3 3-kinase isoenzymes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500545200

21 January 2018

Inositol 1,4,5-trisphosphate 3-kinase A associates with F-actin and dendritic spines via its N terminus

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500545200

21 January 2018

Rat inositol 1,4,5-trisphosphate 3-kinase C is enzymatically specialized for basal cellular inositol trisphosphate phosphorylation and shuttles actively between nucleus and cytoplasm

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500545200

21 January 2018

Recruitment of the yeast MADS-box proteins, ArgRI and Mcm1 by the pleiotropic factor ArgRIII is required for their stability

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500545200

21 January 2018

The human homologue of yeast ArgRIII protein is an inositol phosphate multikinase with predominantly nuclear localization

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500545200

21 January 2018

A role for nuclear inositol 1,4,5-trisphosphate kinase in transcriptional control

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500545200

21 January 2018

Molecular and biochemical characterization of two plant inositol polyphosphate 6-/3-/5-kinases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500545200

21 January 2018

How versatile are inositol phosphate kinases?

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500545200

21 January 2018

The pathway for the production of inositol hexakisphosphate in human cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500545200

21 January 2018

The interaction of coatomer with inositol polyphosphates is conserved in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500545200

21 January 2018

Inositol polyphosphate multikinase (ArgRIII) determines nuclear mRNA export in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500545200

21 January 2018

A phospholipase C-dependent inositol polyphosphate kinase pathway required for efficient messenger RNA export

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500545200

21 January 2018

Second messenger control of chromatin remodeling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500545200

21 January 2018

Inositol hexakisphosphate promotes dynamin I- mediated endocytosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500545200

21 January 2018

Involvement of protein kinase C-epsilon in inositol hexakisphosphate-induced exocytosis in mouse pancreatic beta-cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500545200

21 January 2018

Cytosolic multiple inositol polyphosphate phosphatase in the regulation of cytoplasmic free Ca2+ concentration

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500545200

21 January 2018

Inositol hexakisphosphate increases L-type Ca2+ channel activity by stimulation of adenylyl cyclase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500545200

21 January 2018

Regulation of AP-2-synaptotagmin interaction by inositol high polyphosphates.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500545200

21 January 2018

Inositol hexakisphosphate-mediated regulation of glutamate receptors in rat brain sections

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500545200

21 January 2018

myo-Inositol-1,2,3,4,5,6-hexakisphosphate

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500545200

21 January 2018

Inositol 1,3,4,5-tetrakisphosphate is essential for T lymphocyte development

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500545200

21 January 2018

A novel A-isoform-like inositol 1,4,5-trisphosphate 3-kinase from chicken erythrocytes exhibits alternative splicing and conservation of intron positions between vertebrates and invertebrates

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500545200

21 January 2018

Structure of a human inositol 1,4,5-trisphosphate 3-kinase: substrate binding reveals why it is not a phosphoinositide 3-kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500545200

21 January 2018

Crystal structure of the catalytic core of inositol 1,4,5-trisphosphate 3-kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500545200

21 January 2018

The inhibition of phosphatidylinositol 3-kinase by quercetin and analogs

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500545200

21 January 2018

Flavonoids are selective cyclic GMP phosphodiesterase inhibitors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500545200

21 January 2018

Inhibition of phosphorylase kinase, and tyrosine protein kinase activities by quercetin.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500545200

21 January 2018

Potent and specific inhibitors of protein kinase C of microbial origin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500545200

21 January 2018

The natural tyrosine kinase inhibitor genistein produces cell cycle arrest and apoptosis in Jurkat T-leukemia cells.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500545200

21 January 2018

Hypericin and pseudohypericin specifically inhibit protein kinase C: possible relation to their antiretroviral activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500545200

21 January 2018

Inhibition of protein kinase C by calphostin C is light-dependent

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500545200

21 January 2018

Inhibition of phospholipase C gamma 1 activity by amentoflavone isolated from Selaginella tamariscina

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500545200

21 January 2018

Rottlerin, a novel protein kinase inhibitor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500545200

21 January 2018

Mammalian inositol polyphosphate multikinase synthesizes inositol 1,4,5-trisphosphate and an inositol pyrophosphate

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500545200

21 January 2018

The pp60c-Src inhibitor PP1 is non-competitive against ATP.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500545200

21 January 2018

Prolyl endopeptidase inhibitors from green tea.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500545200

21 January 2018

Suppression of extracellular signals and cell proliferation through EGF receptor binding by (-)-epigallocatechin gallate in human A431 epidermoid carcinoma cells

1 reference

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21 January 2018

The dietary anticancer agent ellagic acid is a potent inhibitor of DNA topoisomerases in vitro.

1 reference

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21 January 2018

Aurintricarboxylic acid, a putative inhibitor of apoptosis, is a potent inhibitor of DNA topoisomerase II in vitro and in Chinese hamster fibrosarcoma cells

1 reference

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21 January 2018

Relationship between flavonoid structure and inhibition of phosphatidylinositol 3-kinase: a comparison with tyrosine kinase and protein kinase C inhibition.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500545200

21 January 2018

The effect of the flavonoids, quercetin, myricetin and epicatechin on the growth and enzyme activities of MCF7 human breast cancer cells.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500545200

21 January 2018

Effects of structurally related flavonoids on cell cycle progression of human melanoma cells: regulation of cyclin-dependent kinases CDK2 and CDK1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500545200

21 January 2018

Inhibition of carcinogenesis by dietary polyphenolic compounds

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500545200

21 January 2018

Prevention of cellular ROS damage by isovitexin and related flavonoids

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500545200

21 January 2018

Chemopreventive effects of tea extracts and various components on human pancreatic and prostate tumor cells in vitro

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500545200

21 January 2018

Green tea constituent epigallocatechin-3-gallate and induction of apoptosis and cell cycle arrest in human carcinoma cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500545200

21 January 2018

Induction of apoptosis by green tea catechins in human prostate cancer DU145 cells.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500545200

21 January 2018

Green tea and cancer chemoprevention

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500545200

21 January 2018

Effect of (-)-epigallocatechin gallate on leukemic blast cells from patients with acute myeloblastic leukemia

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500545200

21 January 2018

Phenolic Compounds from Nymphaea odorata

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500545200

21 January 2018

Laser photosensitization of cells by hypericin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500545200

21 January 2018

Photodynamic effects of hypericin on lipid peroxidation and antioxidant status in melanoma cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500545200

21 January 2018

Hypericin-induced photosensitization of HeLa cells leads to apoptosis or necrosis

1 reference

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21 January 2018

The Activation of the c-Jun N-terminal Kinase and p38 Mitogen-activated Protein Kinase Signaling Pathways Protects HeLa Cells from Apoptosis Following Photodynamic Therapy with Hypericin

1 reference

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21 January 2018

Inhibition of cellular growth and induction of apoptosis in pituitary adenoma cell lines by the protein kinase C inhibitor hypericin: potential therapeutic application

1 reference

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21 January 2018

A photodynamic pathway to apoptosis and necrosis induced by dimethyl tetrahydroxyhelianthrone and hypericin in leukaemic cells: possible relevance to photodynamic therapy

1 reference

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21 January 2018

Hypericin and hypocrellin induced apoptosis in human mucosal carcinoma cells

1 reference

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21 January 2018

Photodynamic therapy with hypericin induces vascular damage and apoptosis in the RIF-1 mouse tumor model.

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https://api.crossref.org/works/10.1074%2FJBC.M500545200

21 January 2018

Hypericin in phototherapy

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21 January 2018

Combination therapy with irinotecan and protein kinase C inhibitors in malignant glioma

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21 January 2018

In vitro and in vivo cytotoxicity of gossypol against central nervous system tumor cell lines

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21 January 2018

Gossypol treatment of recurrent adult malignant gliomas

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21 January 2018

Oral gossypol in the treatment of patients with refractory metastatic breast cancer: a phase I/II clinical trial.

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21 January 2018

Prevention of N-nitrosodiethylamine-induced lung tumorigenesis by ellagic acid and quercetin in mice.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500545200

21 January 2018

Aurintricarboxylic acid inhibits apoptosis and supports proliferation in a haemopoietic growth-factor dependent myeloid cell line

1 reference

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21 January 2018

Activation of the insulin-like growth factor 1 signaling pathway by the antiapoptotic agents aurintricarboxylic acid and evans blue

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21 January 2018

Pretreatment with intraventricular aurintricarboxylic acid decreases infarct size by inhibiting apoptosis following transient global ischemia in gerbils

1 reference

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21 January 2018

Mitigation of tumor necrosis factor alpha cytotoxicity by aurintricarboxylic acid in human peripheral B lymphocytes

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21 January 2018

Cytotoxic effect of the diterpene lactone dehydrocrotonin from Croton cajucara on human promyelocytic leukemia cells.

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21 January 2018

Effects of several polyhydroxylated flavonoids on the growth of B16F10 melanoma and Melan-a melanocyte cell lines: influence of the sequential oxidation state of the flavonoid skeleton

1 reference

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21 January 2018

CrmA protects against apoptosis and ceramide formation in PC12 cells.

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21 January 2018

Chemopreventive effects of coffee bean and rice constituents on colorectal carcinogenesis

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21 January 2018

Antileukemic Activity of Selected Natural Products in Taiwan

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21 January 2018

Echinacoside and caffeoyl conjugates protect collagen from free radical-induced degradation: a potential use of Echinacea extracts in the prevention of skin photodamage

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21 January 2018

Oxidized LDLs Induce Massive Apoptosis of Cultured Human Endothelial Cells Through a Calcium-Dependent Pathway

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21 January 2018

Identifiers

10.1074/JBC.M500545200

1 reference

Europe PubMed Central

11 December 2017

1 reference

Europe PubMed Central

11 December 2017

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