(Q45232462)

English

Thiazolidinediones improve insulin sensitivity in adipose tissue and reduce the hyperlipidaemia without affecting the hyperglycaemia in a transgenic model of type 2 diabetes

scientific article published on 15 December 2004

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

11 December 2017

Thiazolidinediones improve insulin sensitivity in adipose tissue and reduce the hyperlipidaemia without affecting the hyperglycaemia in a transgenic model of type 2 diabetes (English)

1 reference

Europe PubMed Central

PubMed publication ID

11 December 2017

1 reference

based on heuristic

inferred from title

type 2 diabetes

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based on heuristic

inferred from title

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based on heuristic

inferred from title

Martin Haluzík

2

1 reference

Europe PubMed Central

PubMed publication ID

11 December 2017

9

object named as

D LeRoith

1 reference

Europe PubMed Central

PubMed publication ID

11 December 2017

author name string

H Kim

1

1 reference

Europe PubMed Central

PubMed publication ID

11 December 2017

O Gavrilova

3

1 reference

Europe PubMed Central

PubMed publication ID

11 December 2017

S Yakar

4

1 reference

Europe PubMed Central

PubMed publication ID

11 December 2017

J Portas

5

1 reference

Europe PubMed Central

PubMed publication ID

11 December 2017

H Sun

6

1 reference

Europe PubMed Central

PubMed publication ID

11 December 2017

U B Pajvani

7

1 reference

Europe PubMed Central

PubMed publication ID

11 December 2017

P E Scherer

8

1 reference

Europe PubMed Central

PubMed publication ID

11 December 2017

publication date

15 December 2004

1 reference

Europe PubMed Central

PubMed publication ID

11 December 2017

1 reference

Europe PubMed Central

PubMed publication ID

11 December 2017

47

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Europe PubMed Central

PubMed publication ID

11 December 2017

12

1 reference

Europe PubMed Central

PubMed publication ID

11 December 2017

2215-2225

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Europe PubMed Central

PubMed publication ID

11 December 2017

https://scigraph.springernature.com/pub.10.1007/s00125-004-1581-6

0 references

Differential effects of rosiglitazone on skeletal muscle and liver insulin resistance in A-ZIP/F-1 fatless mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/15662559

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Liver-specific disruption of PPARgamma in leptin-deficient mice improves fatty liver but aggravates diabetic phenotypes

1 reference

https://pubmed.ncbi.nlm.nih.gov/15662559

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cellular and molecular mechanisms of non-insulin dependent diabetes mellitus

1 reference

https://pubmed.ncbi.nlm.nih.gov/15662559

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thiazolidinediones in the treatment of insulin resistance and type II diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/15662559

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relative contribution of glycogen synthesis and glycolysis to insulin-mediated glucose uptake. A dose-response euglycemic clamp study in normal and diabetic rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/15662559

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Repetitive blood sampling in unrestrained and unstressed mice using a chronic indwelling right atrial catheterization apparatus

1 reference

https://pubmed.ncbi.nlm.nih.gov/15662559

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PPARS, insulin resistance and type 2 diabetes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15662559

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effects of rosiglitazone on insulin sensitivity, lipolysis, and hepatic and skeletal muscle triglyceride content in patients with type 2 diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/15662559

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thiazolidinediones upregulate impaired fatty acid uptake in skeletal muscle of type 2 diabetic subjects

1 reference

https://pubmed.ncbi.nlm.nih.gov/15662559

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stimulation of adipogenesis in fibroblasts by PPAR gamma 2, a lipid-activated transcription factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/15662559

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Muscle-specific Pparg deletion causes insulin resistance

1 reference

https://pubmed.ncbi.nlm.nih.gov/15662559

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rosiglitazone improves downstream insulin receptor signaling in type 2 diabetic patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/15662559

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impaired multimerization of human adiponectin mutants associated with diabetes. Molecular structure and multimer formation of adiponectin.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15662559

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Time courses of changes in hepatic and skeletal muscle insulin action and GLUT4 protein in skeletal muscle after STZ injection.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15662559

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin-like growth factor 1 (IGF-1)-induced twist expression is involved in the anti-apoptotic effects of the IGF-1 receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/15662559

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of thiazolidinediones on plasma adiponectin levels in normal, obese, and type 2 diabetic subjects

1 reference

https://pubmed.ncbi.nlm.nih.gov/15662559

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolic effects of troglitazone monotherapy in type 2 diabetes mellitus. A randomized, double-blind, placebo-controlled trial.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15662559

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Troglitazone increases the number of small adipocytes without the change of white adipose tissue mass in obese Zucker rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/15662559

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential activation of adipogenesis by multiple PPAR isoforms.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15662559

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Complex distribution, not absolute amount of adiponectin, correlates with thiazolidinedione-mediated improvement in insulin sensitivity

1 reference

https://pubmed.ncbi.nlm.nih.gov/15662559

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

New drug targets for type 2 diabetes and the metabolic syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/15662559

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Development of insulin resistance and reversal by thiazolidinediones in C2C12 skeletal muscle cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/15662559

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Muscle-specific PPARgamma-deficient mice develop increased adiposity and insulin resistance but respond to thiazolidinediones

1 reference

https://pubmed.ncbi.nlm.nih.gov/15662559

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Potentiation of insulin signaling in tissues of Zucker obese rats after acute and long-term treatment with PPARgamma agonists

1 reference

https://pubmed.ncbi.nlm.nih.gov/15662559

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Liver peroxisome proliferator-activated receptor gamma contributes to hepatic steatosis, triglyceride clearance, and regulation of body fat mass.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15662559

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adipose tissue is required for the antidiabetic, but not for the hypolipidemic, effect of thiazolidinediones

1 reference

https://pubmed.ncbi.nlm.nih.gov/15662559

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Efficacy and safety of troglitazone in the treatment of lipodystrophy syndromes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15662559

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacogenetic evidence that cd36 is a key determinant of the metabolic effects of pioglitazone

1 reference

https://pubmed.ncbi.nlm.nih.gov/15662559

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Up-regulation of peroxisome proliferator-activated receptors (PPAR-alpha) and PPAR-gamma messenger ribonucleic acid expression in the liver in murine obesity: troglitazone induces expression of PPAR-gamma-responsive adipose tissue-specific genes in

1 reference

https://pubmed.ncbi.nlm.nih.gov/15662559

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pioglitazone reduces hepatic fat content and augments splanchnic glucose uptake in patients with type 2 diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/15662559

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Treatment of insulin resistance with peroxisome proliferator-activated receptor gamma agonists

1 reference

https://pubmed.ncbi.nlm.nih.gov/15662559

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanism of troglitazone action in type 2 diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/15662559

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional inactivation of the IGF-I and insulin receptors in skeletal muscle causes type 2 diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/15662559

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of glucose transport in cultured muscle cells by novel hypoglycemic agents

1 reference

https://pubmed.ncbi.nlm.nih.gov/15662559

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differences in lipid profiles of patients given rosiglitazone followed by pioglitazone

1 reference

https://pubmed.ncbi.nlm.nih.gov/15662559

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Redistribution of substrates to adipose tissue promotes obesity in mice with selective insulin resistance in muscle

1 reference

https://pubmed.ncbi.nlm.nih.gov/15662559

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Efficacy and metabolic effects of metformin and troglitazone in type II diabetes mellitus.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15662559

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adiponectin--its role in metabolism and beyond

1 reference

https://pubmed.ncbi.nlm.nih.gov/15662559

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin and dietary fructose induce stearoyl-CoA desaturase 1 gene expression of diabetic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/15662559

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comprehensive messenger ribonucleic acid profiling reveals that peroxisome proliferator-activated receptor gamma activation has coordinate effects on gene expression in multiple insulin-sensitive tissues

1 reference

https://pubmed.ncbi.nlm.nih.gov/15662559

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure-function studies of the adipocyte-secreted hormone Acrp30/adiponectin. Implications fpr metabolic regulation and bioactivity

1 reference

https://pubmed.ncbi.nlm.nih.gov/15662559

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Troglitazone action is independent of adipose tissue

1 reference

https://pubmed.ncbi.nlm.nih.gov/15662559

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ACRP30/adiponectin: an adipokine regulating glucose and lipid metabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/15662559

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thiazolidinediones (PPARgamma agonists) but not PPARalpha agonists increase IRS-2 gene expression in 3T3-L1 and human adipocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/15662559

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rosiglitazone fails to improve hypertriglyceridemia and glucose tolerance in CD36-deficient BN.SHR4 congenic rat strain

1 reference

https://pubmed.ncbi.nlm.nih.gov/15662559

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin-sensitizing effect of rosiglitazone (BRL-49653) by regulation of glucose transporters in muscle and fat of Zucker rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/15662559

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Radiometric assays for glycerol, glucose, and glycogen

1 reference

https://pubmed.ncbi.nlm.nih.gov/15662559

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peroxisome proliferator-activated receptor-alpha agonist treatment in a transgenic model of type 2 diabetes reverses the lipotoxic state and improves glucose homeostasis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15662559

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of adipocyte complement-related protein of 30 kilodaltons by PPARgamma agonists: a potential mechanism of insulin sensitization

1 reference

https://pubmed.ncbi.nlm.nih.gov/15662559

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S00125-004-1581-6

1 reference

Europe PubMed Central

PubMed publication ID

11 December 2017

Dimensions Publication ID

0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

11 December 2017

ResearchGate publication ID

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