(Q45233639)

11 December 2017

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title

Challenges translating breast cancer gene signatures into the clinic (English)

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11 December 2017

4

Jorge S Reis-Filho

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11 December 2017

1

Britta Weigelt

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11 December 2017

3

Alan Ashworth

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11 December 2017

Lajos Pusztai

2

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PubMed ID

21878891

11 December 2017

language of work or name

English

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publication date

30 August 2011

1 reference

Nature Reviews Clinical Oncology

11 December 2017

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11 December 2017

9

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11 December 2017

58-64

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11 December 2017

1

1 reference

Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: an overview of the randomised trials

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Gene-expression signatures in breast cancer

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Molecular profiling: moving away from tumor philately

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Molecular portraits of human breast tumours

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Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications

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Repeated observation of breast tumor subtypes in independent gene expression data sets

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The molecular portraits of breast tumors are conserved across microarray platforms

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Predicting prognosis of breast cancer with gene signatures: are we lost in a sea of data?

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Phenotypic and molecular characterization of the claudin-low intrinsic subtype of breast cancer

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Gene-expression profiles predict survival of patients with lung adenocarcinoma

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Gene expression profiling predicts clinical outcome of breast cancer

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Breast cancer assessment tools and optimizing adjuvant therapy.

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Do predictive signatures really predict response to cancer chemotherapy?

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Deriving chemosensitivity from cell lines: Forensic bioinformatics and reproducible research in high-throughput biology

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Clinical evaluation of chemotherapy response predictors developed from breast cancer cell lines

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Effect of training-sample size and classification difficulty on the accuracy of genomic predictors

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.125

Microarrays: retracing steps

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.125

Biological Processes Associated with Breast Cancer Clinical Outcome Depend on the Molecular Subtypes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.125

Meta-analysis of gene expression profiles in breast cancer: toward a unified understanding of breast cancer subtyping and prognosis signatures

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.125

Breast cancer molecular profiling with single sample predictors: a retrospective analysis

31 March 2020

1 reference

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Supervised risk predictor of breast cancer based on intrinsic subtypes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.125

Concordance of clinical and molecular breast cancer subtyping in the context of preoperative chemotherapy response

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.125

The effect of the stromal component of breast tumours on prediction of clinical outcome using gene expression microarray analysis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.125

Molecular classification of breast cancer: limitations and potential

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1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.125

Pitfalls in the use of DNA microarray data for diagnostic and prognostic classification

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1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.125

Microarray-based class discovery for molecular classification of breast cancer: analysis of interobserver agreement

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.125

Calibration and discriminatory accuracy of prognosis calculation for breast cancer with the online Adjuvant! program: a hospital-based retrospective cohort study.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.125

Molecular profiling currently offers no more than tumour morphology and basic immunohistochemistry

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.125

T-cell metagene predicts a favorable prognosis in estrogen receptor-negative and HER2-positive breast cancers.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.125

A robust classifier of high predictive value to identify good prognosis patients in ER-negative breast cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.125

Immunohistochemical demonstration of oestrogen and progesterone receptors: correlation of standards achieved on in house tumours with that achieved on external quality assessment material in over 150 laboratories from 26 countries

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.125

Estrogen- and progesterone-receptor status in ECOG 2197: comparison of immunohistochemistry by local and central laboratories and quantitative reverse transcription polymerase chain reaction by central laboratory.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.125

The MicroArray Quality Control (MAQC) project shows inter- and intraplatform reproducibility of gene expression measurements

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.125

The MicroArray Quality Control (MAQC)-II study of common practices for the development and validation of microarray-based predictive models

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1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.125

Use of 70-gene signature to predict prognosis of patients with node-negative breast cancer: a prospective community-based feasibility study (RASTER).

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.125

Predictive signatures for chemotherapy sensitivity in breast cancer: are they ready for use in the clinic?

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.125

Pharmacogenomic predictor of sensitivity to preoperative chemotherapy with paclitaxel and fluorouracil, doxorubicin, and cyclophosphamide in breast cancer.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.125

Evaluation of a 30-gene paclitaxel, fluorouracil, doxorubicin, and cyclophosphamide chemotherapy response predictor in a multicenter randomized trial in breast cancer.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.125

Genome remodelling in a basal-like breast cancer metastasis and xenograft

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1 reference

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Mutational evolution in a lobular breast tumour profiled at single nucleotide resolution

31 March 2020

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Molecular predictors of response to trastuzumab and lapatinib in breast cancer.

31 March 2020

1 reference

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Complex landscapes of somatic rearrangement in human breast cancer genomes

31 March 2020

1 reference

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Microarrays and breast cancer clinical studies: forgetting what we have not yet learnt

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1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.125

Deflating the Genomic Bubble

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1 reference

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Genetic Interactions in Cancer Progression and Treatment

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1 reference

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Prognostic value of Ki67 expression after short-term presurgical endocrine therapy for primary breast cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.125

A marker of homologous recombination predicts pathologic complete response to neoadjuvant chemotherapy in primary breast cancer

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1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.125

Using functional genetics to understand breast cancer biology

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1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2011.125

Personalizing cancer treatment in the age of global genomic analyses: PALB2 gene mutations and the response to DNA damaging agents in pancreatic cancer

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1 reference

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Subtype-specific genomic alterations define new targets for soft-tissue sarcoma therapy

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1 reference

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The evolving war on cancer

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1 reference

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Does massively parallel DNA resequencing signify the end of histopathology as we know it?

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1 reference

12 December 2020

Estrogen receptor status in breast cancer is associated with remarkably distinct gene expression patterns

1 reference

12 December 2020

The contribution of gene expression profiling to breast cancer classification, prognostication and prediction: a retrospective of the last decade

1 reference

12 December 2020

Gene-expression profiles to predict distant metastasis of lymph-node-negative primary breast cancer

1 reference

12 December 2020

10.1038/NRCLINONC.2011.125

Identifiers

DOI

1 reference

11 December 2017

1 reference

PubMed ID

21878891