(Q45234608)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15665333%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

title

Kinetic analysis of oxidation of coumarins by human cytochrome P450 2A6 (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15665333%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15665333%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

author name string

Keon-Hee Kim

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15665333%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

M Wade Calcutt

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15665333%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

F Peter Guengerich

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15665333%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

language of work or name

English

0 references

publication date

22 January 2005

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15665333%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

7 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15665333%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

volume

280

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15665333%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

issue

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15665333%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

page(s)

12279-12291

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15665333%20AND%20SRC:MED&resulttype=core&format=json

Steady-state analysis of kinetic isotope effects in enzymic reactions

7 January 2020

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411019200

Bacterial cytochromes P-450.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411019200

Human extrahepatic cytochromes P450: function in xenobiotic metabolism and tissue-selective chemical toxicity in the respiratory and gastrointestinal tracts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411019200

Isolation and sequence of a human cytochrome P-450 cDNA clone

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411019200

A spectrofluorimetric study of the 7-hydroxylation of coumarin by liver microsomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411019200

The CYP2A3 gene product catalyzes coumarin 7-hydroxylation in human liver microsomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411019200

Identification of the human liver cytochrome P-450 responsible for coumarin 7-hydroxylase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411019200

Cytochrome P450 2E1 and 2A6 enzymes as major catalysts for metabolic activation of N-nitrosodialkylamines and tobacco-related nitrosamines in human liver microsomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411019200

Evidence for cytochrome P450 2A6 and 3A4 as major catalysts for N'-nitrosonornicotine alpha-hydroxylation by human liver microsomes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411019200

21 January 2018

Metabolic polymorphisms

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411019200

Genetic variation of CYP2A6, smoking, and risk of cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411019200

Nicotine metabolism defect reduces smoking

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411019200

Formation of indigo by recombinant mammalian cytochrome P450.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411019200

Oxidation of indole by cytochrome P450 enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411019200

Generation of new protein kinase inhibitors utilizing cytochrome p450 mutant enzymes for indigoid synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411019200

Oxidations of p-alkoxyacylanilides catalyzed by human cytochrome P450 1A2: structure-activity relationships and simulation of rate constants of individual steps in catalysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411019200

Oxidation of methoxyphenethylamines by cytochrome P450 2D6. Analysis of rate-limiting steps.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411019200

Rate-limiting steps in cytochrome P450 catalysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411019200

Random mutagenesis of human cytochrome p450 2A6 and screening with indole oxidation products

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411019200

Common and uncommon cytochrome P450 reactions related to metabolism and chemical toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411019200

Hydroxylation by the hydroperoxy-iron species in cytochrome P450 enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411019200

Synthesis and biological evaluation of aeroplysinin analogues: a new class of receptor tyrosine kinase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411019200

The Metabolism of Umbelliferone and Herniarin in Rats and by the Rat Intestinal Microflora

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411019200

Structure Elucidation of 2,4-Dinitrophenylhydrazone Derivatives of Carbonyl Compounds in Ambient Air by HPLC/MS and Multiple MS/MS Using Atmospheric Chemical Ionization in the Negative Ion Mode

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411019200

Characterization by liquid chromatography-nuclear magnetic resonance spectroscopy and liquid chromatography-mass spectrometry of two coupled oxidative-conjugative metabolic pathways for 7-ethoxycoumarin in human liver microsomes treated with alameth

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411019200

Identification of the cytochromes P450 that catalyze coumarin 3,4-epoxidation and 3-hydroxylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411019200

Steady-state and pre-steady-state kinetic analysis of dNTP insertion opposite 8-oxo-7,8-dihydroguanine by Escherichia coli polymerases I exo- and II exo-.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411019200

Kinetic isotope effects and 'metabolic switching' in cytochrome P450-catalyzed reactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411019200

Immunochemical Study on the Electron Pathway from NADH to Cytochrome P-450 of Liver Microsomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411019200

Kinetics of ferric cytochrome P450 reduction by NADPH-cytochrome P450 reductase: rapid reduction in the absence of substrate and variations among cytochrome P450 systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411019200

Lack of electron transfer from cytochrome b5 in stimulation of catalytic activities of cytochrome P450 3A4. Characterization of a reconstituted cytochrome P450 3A4/NADPH-cytochrome P450 reductase system and studies with apo-cytochrome b5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411019200

4-cyanopyridine, a versatile spectroscopic probe for cytochrome P450 BM3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411019200

Oxygenated cytochrome P-450 and its possible role in enzymic hydroxylation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411019200

Spectral intermediates in the reaction of oxygen with purified liver microsomal cytochrome P-450

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411019200

Characterization of the oxygenated intermediate of the thermophilic cytochrome P450 CYP119.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411019200

Roles of NADPH-P450 reductase and apo- and holo-cytochrome b5 on xenobiotic oxidations catalyzed by 12 recombinant human cytochrome P450s expressed in membranes of Escherichia coli.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411019200

Cytochrome P450-catalyzed hydroxylation of hydrocarbons: kinetic deuterium isotope effects for the hydroxylation of an ultrafast radical clock.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411019200

Minimal kinetic mechanism and general equation for deuterium isotope effects on enzymic reactions: uncertainty of detecting a rate-limiting step

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411019200

The Pennsylvania State University College of Medicine 1991 Bernard B. Brodie Lecture. Insights into deuterium isotope effects on the metabolism of steroid hormones and foreign compounds by cytochrome P-450 enzymes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411019200

Theory for the observed isotope effects on the formation of multiple products by different kinetic mechanisms of cytochrome P450 enzymes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411019200

Cyclooxygenase-2-deficient mice are resistant to endotoxin-induced inflammation and death

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411019200

Methamphetamine induces neuronal apoptosis via cross-talks between endoplasmic reticulum and mitochondria-dependent death cascades

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411019200

Kinetic characterization of compound I formation in the thermostable cytochrome P450 CYP119.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411019200

Crystal structure of human cytochrome P450 2C9 with bound warfarin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411019200

Structure of human microsomal cytochrome P450 2C8. Evidence for a peripheral fatty acid binding site

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411019200

Crystal structures of human cytochrome P450 3A4 bound to metyrapone and progesterone

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411019200

The structure of human microsomal cytochrome P450 3A4 determined by X-ray crystallography to 2.05-A resolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411019200

P450BM-3: reduction by NADPH and sodium dithionite

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411019200

A thermodynamic model of regulation: modulation of redox equilibria in camphor monoxygenase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411019200

Redox control of the catalytic cycle of flavocytochrome P-450 BM3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411019200

The catalytic pathway of cytochrome p450cam at atomic resolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411019200

An efficient synthesis of furanocoumarins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411019200

21 January 2018

Identifiers

DOI

10.1074/JBC.M411019200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15665333%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

1 reference