(Q45258141)

English

Hormone-sensitive lipase knockout mice have increased hepatic insulin sensitivity and are protected from short-term diet-induced insulin resistance in skeletal muscle and heart

scientific article published on 8 February 2005

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scholarly article

1 reference

Europe PubMed Central

11 December 2017

Hormone-sensitive lipase knockout mice have increased hepatic insulin sensitivity and are protected from short-term diet-induced insulin resistance in skeletal muscle and heart (English)

1 reference

Europe PubMed Central

11 December 2017

0 references

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based on heuristic

inferred from title

insulin resistance

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based on heuristic

inferred from title

Gerald I. Shulman

10

object named as

Gerald I Shulman

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Europe PubMed Central

11 December 2017

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object named as

Gary Cline

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Europe PubMed Central

11 December 2017

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object named as

Jason K Kim

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Europe PubMed Central

11 December 2017

Takamasa Higashimori

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object named as

Takamasa Higashimori

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Europe PubMed Central

11 December 2017

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object named as

Hyo-Jeong Kim

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Europe PubMed Central

11 December 2017

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object named as

Jianying Dong

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Europe PubMed Central

11 December 2017

author name string

So-Young Park

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Europe PubMed Central

11 December 2017

Shupei Wang

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Europe PubMed Central

11 December 2017

Yoon-Jung Kim

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Europe PubMed Central

11 December 2017

Hong Li

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Europe PubMed Central

11 December 2017

Marc Prentki

9

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Europe PubMed Central

11 December 2017

Grant A Mitchell

11

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Europe PubMed Central

11 December 2017

publication date

8 February 2005

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Europe PubMed Central

11 December 2017

American Journal of Physiology - Endocrinology and Metabolism

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11 December 2017

289

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1

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E30-9

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11 December 2017

Identification of novel phosphorylation sites in hormone-sensitive lipase that are phosphorylated in response to isoproterenol and govern activation properties in vitro

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00251.2004

21 January 2018

A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00251.2004

21 January 2018

Free fatty acids in obesity and type 2 diabetes: defining their role in the development of insulin resistance and beta-cell dysfunction.

1 reference

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21 January 2018

Effects of acute changes of plasma free fatty acids on intramyocellular fat content and insulin resistance in healthy subjects

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00251.2004

21 January 2018

Five-hour fatty acid elevation increases muscle lipids and impairs glycogen synthesis in the rat.

1 reference

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21 January 2018

Adipose tissue is required for the antidiabetic, but not for the hypolipidemic, effect of thiazolidinediones

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00251.2004

21 January 2018

Lilly lecture 1987. The triumvirate: beta-cell, muscle, liver. A collusion responsible for NIDDM.

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00251.2004

21 January 2018

The cardiac phenotype induced by PPARalpha overexpression mimics that caused by diabetes mellitus

1 reference

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A critical role for PPARalpha-mediated lipotoxicity in the pathogenesis of diabetic cardiomyopathy: modulation by dietary fat content.

1 reference

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Hormone-sensitive lipase-independent adipocyte lipolysis during beta-adrenergic stimulation, fasting, and dietary fat loading.

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00251.2004

21 January 2018

Coordinated regulation of hormone-sensitive lipase and lipoprotein lipase in human adipose tissue in vivo: implications for the control of fat storage and fat mobilization.

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00251.2004

21 January 2018

Hormone-sensitive lipase deficiency in mice changes the plasma lipid profile by affecting the tissue-specific expression pattern of lipoprotein lipase in adipose tissue and muscle

1 reference

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21 January 2018

Defective fatty acid uptake modulates insulin responsiveness and metabolic responses to diet in CD36-null mice

1 reference

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21 January 2018

Resistance to high-fat diet-induced obesity and altered expression of adipose-specific genes in HSL-deficient mice

1 reference

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21 January 2018

Molecular mechanisms regulating hormone-sensitive lipase and lipolysis

1 reference

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21 January 2018

Hormone-Sensitive Lipase: Sequence, Expression, and Chromosomal Localization to 19 cent-q13.3

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00251.2004

21 January 2018

Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00251.2004

21 January 2018

Banting Lecture. Insulin action, diabetogenes, and the cause of type II diabetes

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00251.2004

21 January 2018

Unraveling the mechanism of action of thiazolidinediones

1 reference

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21 January 2018

Differential effects of interleukin-6 and -10 on skeletal muscle and liver insulin action in vivo

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00251.2004

21 January 2018

Tissue-specific overexpression of lipoprotein lipase causes tissue-specific insulin resistance

1 reference

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21 January 2018

Differential effects of rosiglitazone on skeletal muscle and liver insulin resistance in A-ZIP/F-1 fatless mice

1 reference

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21 January 2018

The putative role of the hormone-sensitive lipase gene in the pathogenesis of Type II diabetes mellitus and abdominal obesity

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00251.2004

21 January 2018

Intramyocellular lipid concentrations are correlated with insulin sensitivity in humans: a 1H NMR spectroscopy study.

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00251.2004

21 January 2018

Hormone-sensitive lipase null mice exhibit signs of impaired insulin sensitivity whereas insulin secretion is intact

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00251.2004

21 January 2018

Increased lipolysis and its consequences on gluconeogenesis in non-insulin-dependent diabetes mellitus

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00251.2004

21 January 2018

Targeted disruption of hormone-sensitive lipase results in male sterility and adipocyte hypertrophy, but not in obesity

1 reference

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21 January 2018

Can glucocorticoid homeostasis explain the antiatherogenic effect of peripheral adiposity?

1 reference

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21 January 2018

Serine/threonine phosphorylation of IRS-1 triggers its degradation: possible regulation by tyrosine phosphorylation

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00251.2004

21 January 2018

Intramyocellular triglyceride content is a determinant of in vivo insulin resistance in humans: a 1H-13C nuclear magnetic resonance spectroscopy assessment in offspring of type 2 diabetic parents.

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00251.2004

21 January 2018

Contrasting effects of IRS-1 versus IRS-2 gene disruption on carbohydrate and lipid metabolism in vivo.

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00251.2004

21 January 2018

The glucose fatty-acid cycle. Its role in insulin sensitivity and the metabolic disturbances of diabetes mellitus

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00251.2004

21 January 2018

Banting lecture 1988. Role of insulin resistance in human disease

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00251.2004

21 January 2018

Mechanism of free fatty acid-induced insulin resistance in humans

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00251.2004

21 January 2018

The diabetic heart: metabolic causes for the development of a cardiomyopathy

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00251.2004

21 January 2018

A role for hormone-sensitive lipase in glucose-stimulated insulin secretion: a study in hormone-sensitive lipase-deficient mice.

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00251.2004

21 January 2018

Insulin/IGF-1 and TNF-alpha stimulate phosphorylation of IRS-1 at inhibitory Ser307 via distinct pathways

1 reference

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21 January 2018

Absence of hormone-sensitive lipase inhibits obesity and adipogenesis in Lep ob/ob mice

1 reference

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21 January 2018

Cellular mechanisms of insulin resistance

1 reference

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21 January 2018

The hormone resistin links obesity to diabetes

1 reference

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21 January 2018

Variation in the promoter of the human hormone sensitive lipase gene shows gender specific effects on insulin and lipid levels: results from the Ely study

1 reference

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21 January 2018

Increased hepatic insulin sensitivity together with decreased hepatic triglyceride stores in hormone-sensitive lipase-deficient mice

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00251.2004

21 January 2018

The adipose tissue phenotype of hormone-sensitive lipase deficiency in mice

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00251.2004

21 January 2018

The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity

1 reference

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21 January 2018

Hormone-sensitive lipase--a multipurpose enzyme in lipid metabolism

1 reference

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21 January 2018

Mechanism by which fatty acids inhibit insulin activation of insulin receptor substrate-1 (IRS-1)-associated phosphatidylinositol 3-kinase activity in muscle

1 reference

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21 January 2018

Reversal of obesity- and diet-induced insulin resistance with salicylates or targeted disruption of Ikkbeta

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Decreased fatty acid esterification compensates for the reduced lipolytic activity in hormone-sensitive lipase-deficient white adipose tissue

1 reference

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21 January 2018

Identifiers

10.1152/AJPENDO.00251.2004

1 reference

Europe PubMed Central

11 December 2017

1 reference

Europe PubMed Central

11 December 2017

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