(Q45318222)

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Pre-NOTCH Expression and Processing

An instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-1912422)

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8 July 2022

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8 July 2022

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https://identifiers.org/reactome:R-HSA-1912422

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Pre-NOTCH Processing in the Endoplasmic Reticulum

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Pre-NOTCH Transcription and Translation

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Pre-NOTCH Processing in Golgi

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Modification of epidermal growth factor-like repeats with O-fucose. Molecular cloning and expression of a novel GDP-fucose protein O-fucosyltransferase

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8 July 2022

Fringe boundaries coincide with Notch-dependent patterning centres in mammals and alter Notch-dependent development in Drosophila

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8 July 2022

Epithelial to mesenchymal transition is mechanistically linked with stem cell signatures in prostate cancer cells

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Intracellular cleavage of Notch leads to a heterodimeric receptor on the plasma membrane

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8 July 2022

MicroRNA miR-34 inhibits human pancreatic cancer tumor-initiating cells

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Fringe modulation of Jagged1-induced Notch signaling requires the action of beta 4galactosyltransferase-1

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Fringe modifies O-fucose on mouse Notch1 at epidermal growth factor-like repeats within the ligand-binding site and the Abruptex region

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A family of mammalian Fringe genes implicated in boundary determination and the Notch pathway

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8 July 2022

Modulation of microRNA expression in human T-cell development: targeting of NOTCH3 by miR-150.

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MicroRNA-34a suppresses invasion through downregulation of Notch1 and Jagged1 in cervical carcinoma and choriocarcinoma cells.

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Protein O-fucosyltransferase 1 (Pofut1) regulates lymphoid and myeloid homeostasis through modulation of Notch receptor ligand interactions

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Roles for proteolysis and trafficking in notch maturation and signal transduction

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Calcium depletion dissociates and activates heterodimeric notch receptors

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8 July 2022

The Notch1 receptor is cleaved constitutively by a furin-like convertase

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MicroRNA-206 targets notch3, activates apoptosis, and inhibits tumor cell migration and focus formation

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8 July 2022

Control of vertebrate multiciliogenesis by miR-449 through direct repression of the Delta/Notch pathway

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Epigenetically reprogramming metastatic tumor cells with an embryonic microenvironment

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Fringe is a glycosyltransferase that modifies Notch

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Effects of S1 Cleavage on the Structure, Surface Export, and Signaling Activity of Human Notch1 and Notch2

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8 July 2022

Regulation of mammalian Notch signaling and embryonic development by the protein O-glucosyltransferase Rumi

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8 July 2022

Roles of Pofut1 and O-fucose in mammalian Notch signaling

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8 July 2022

MicroRNA-34a inhibits glioblastoma growth by targeting multiple oncogenes

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8 July 2022

Rumi is a CAP10 domain glycosyltransferase that modifies Notch and is required for Notch signaling.

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Involvement of epigenetically silenced microRNA-181c in gastric carcinogenesis

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8 July 2022

Glycosyltransferase activity of Fringe modulates Notch-Delta interactions.

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8 July 2022

Identifiers

1 reference

8 July 2022

(Q45318222)

Pre-NOTCH Expression and Processing

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