(Q45361823)

13 December 2017

title

Synthetic virus-like particles and conformationally constrained peptidomimetics in vaccine design (English)

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13 December 2017

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5

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13 December 2017

Tina Riedel

1

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13 December 2017

Arin Ghasparian

2

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13 December 2017

Kerstin Moehle

3

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13 December 2017

Peter Rusert

4

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13 December 2017

John A Robinson

6

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13 December 2017

language of work or name

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11 November 2011

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13 December 2017

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13 December 2017

volume

12

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13 December 2017

issue

18

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13 December 2017

page(s)

2829-2836

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Vaccines: the Fourth Century

13 December 2017

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Current status of short synthetic peptides as vaccines

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The who, how and where of antigen presentation to B cells

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Functional anatomy of T cell activation and synapse formation

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The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors

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The structural biology of Toll-like receptors

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Synthetic virus-like particles from self-assembling coiled-coil lipopeptides and their use in antigen display to the immune system

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Engineered synthetic virus-like particles and their use in vaccine delivery

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Highly immunogenic and totally synthetic lipopeptides as self-adjuvanting immunocontraceptive vaccines.

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A totally synthetic vaccine of generic structure that targets Toll-like receptor 2 on dendritic cells and promotes antibody or cytotoxic T cell responses

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Soluble proteins induce strong CD8+ T cell and antibody responses through electrostatic association with simple cationic or anionic lipopeptides that target TLR2.

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Recognition of lipopeptide patterns by Toll-like receptor 2-Toll-like receptor 6 heterodimer

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Crystal structure of the TLR1-TLR2 heterodimer induced by binding of a tri-acylated lipopeptide

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Single-particle cryoelectron microscopy analysis reveals the HIV-1 spike as a tripod structure

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Structures of the CCR5 N Terminus and of a Tyrosine-Sulfated Antibody with HIV-1 gp120 and CD4

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Structure of a V3-containing HIV-1 gp120 core

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Crystal structures of human immunodeficiency virus type 1 (HIV-1) neutralizing antibody 2219 in complex with three different V3 peptides reveal a new binding mode for HIV-1 cross-reactivity

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Structure of Antibody F425-B4e8 in Complex with a V3 Peptide Reveals a New Binding Mode for HIV-1 Neutralization

21 January 2018

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Structure determination of an anti-HIV-1 Fab 447-52D–peptide complex from an epitaxially twinned data set

21 January 2018

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Conserved structural elements in the V3 crown of HIV-1 gp120

21 January 2018

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Analysis of the neutralization breadth of the anti-V3 antibody F425-B4e8 and re-assessment of its epitope fine specificity by scanning mutagenesis

21 January 2018

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Beta-hairpin peptidomimetics: design, structures and biological activities

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21 January 2018

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β-Sheet 13C structuring shifts appear only at the H-bonded sites of hairpins

21 January 2018

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Interpreting protein chemical shift data

21 January 2018

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Divergent effects of cell environment on HIV entry inhibitor activity.

21 January 2018

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Interaction of the gp120 V1V2 loop with a neighboring gp120 unit shields the HIV envelope trimer against cross-neutralizing antibodies

21 January 2018

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Structure-based approach to rationally design a chimeric protein for an effective vaccine against Group B Streptococcus infections

21 January 2018

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Crystal structure of a human immunodeficiency virus type 1 neutralizing antibody, 50.1, in complex with its V3 loop peptide antigen

21 January 2018

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Crystal structure of the principal neutralization site of HIV-1

21 January 2018

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Dual conformations for the HIV-1 gp120 V3 loop in complexes with different neutralizing fabs

21 January 2018

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Recurring conformation of the human immunodeficiency virus type 1 gp120 V3 loop

21 January 2018

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Solution conformational preferences of immunogenic peptides derived from the principal neutralizing determinant of the HIV-1 envelope glycoprotein gp120.

21 January 2018

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Conformational model for the consensus V3 loop of the envelope protein gp120 of HIV-1 in a 20% trifluoroethanol/water solution

21 January 2018

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Structure-based design of a constrained peptide mimic of the HIV-1 V3 loop neutralization site

21 January 2018

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A structure-based approach to a synthetic vaccine for HIV-1.

21 January 2018

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A cis proline turn linking two beta-hairpin strands in the solution structure of an antibody-bound HIV-1IIIB V3 peptide

21 January 2018

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NMR structure of an anti-gp120 antibody complex with a V3 peptide reveals a surface important for co-receptor binding

21 January 2018

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Molecular switch for alternative conformations of the HIV-1 V3 region: implications for phenotype conversion

21 January 2018

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Mimicking the structure of the V3 epitope bound to HIV-1 neutralizing antibodies

21 January 2018

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An optimally constrained V3 peptide is a better immunogen than its linear homolog or HIV-1 gp120

21 January 2018

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Optimization of human immunodeficiency virus type 1 envelope glycoproteins with V1/V2 deleted, using virus evolution

21 January 2018

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The V1, V2, and V3 regions of the human immunodeficiency virus type 1 envelope differentially affect the viral phenotype in an isolate-dependent manner

21 January 2018

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Effect of major deletions in the V1 and V2 loops of a macrophage-tropic HIV type 1 isolate on viral envelope structure, cell entry, and replication

21 January 2018

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The program XEASY for computer-supported NMR spectral analysis of biological macromolecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201100586

Torsion angle dynamics for NMR structure calculation with the new program DYANA

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201100586

MOLMOL: a program for display and analysis of macromolecular structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201100586

Antigen presentation by dendritic cells in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201100586

21 January 2018

Identifiers

DOI

10.1002/CBIC.201100586

1 reference

13 December 2017

1 reference