(Q45366717)

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Characterization of antigenic regions in the porcine reproductive and respiratory syndrome virus by the use of peptide-specific serum antibodies

scientific article published on 7 May 2011

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Europe PubMed Central

PubMed publication ID

13 December 2017

Characterization of antigenic regions in the porcine reproductive and respiratory syndrome virus by the use of peptide-specific serum antibodies (English)

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Europe PubMed Central

PubMed publication ID

13 December 2017

porcine reproductive and respiratory syndrome

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based on heuristic

inferred from title

porcine reproductive and respiratory syndrome virus

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porcine reproductive and respiratory syndrome virus

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based on heuristic

inferred from title

Hans J Nauwynck

6

object named as

Hans Nauwynck

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Europe PubMed Central

PubMed publication ID

13 December 2017

author name string

Merijn Vanhee

1

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Europe PubMed Central

PubMed publication ID

13 December 2017

Wander Van Breedam

2

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Europe PubMed Central

PubMed publication ID

13 December 2017

Sarah Costers

3

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Europe PubMed Central

PubMed publication ID

13 December 2017

Marc Geldhof

4

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Europe PubMed Central

PubMed publication ID

13 December 2017

Ytse Noppe

5

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Europe PubMed Central

PubMed publication ID

13 December 2017

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publication date

7 May 2011

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Europe PubMed Central

PubMed publication ID

13 December 2017

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Europe PubMed Central

PubMed publication ID

13 December 2017

29

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Europe PubMed Central

PubMed publication ID

13 December 2017

29-30

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Europe PubMed Central

PubMed publication ID

13 December 2017

4794-4804

1 reference

Europe PubMed Central

PubMed publication ID

13 December 2017

Isolation of swine infertility and respiratory syndrome virus (isolate ATCC VR-2332) in North America and experimental reproduction of the disease in gnotobiotic pigs

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Assessment of the economic impact of porcine reproductive and respiratory syndrome on swine production in the United States

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Mystery swine disease in the Netherlands: The isolation of Lelystad virus

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Experimental reproduction of porcine epidemic abortion and respiratory syndrome (mystery swine disease) by infection with Lelystad virus: Koch's postulates fulfilled

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Porcine reproductive and respiratory syndrome virus infection in the boar: a review

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The combination of PRRS virus and bacterial endotoxin as a model for multifactorial respiratory disease in pigs

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Virus quantification and identification of cellular targets in the lungs and lymphoid tissues of pigs at different time intervals after inoculation with porcine reproductive and respiratory syndrome virus (PRRSV).

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Nidovirales: evolving the largest RNA virus genome

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Molecular analysis of the ORFs 3 to 7 of porcine reproductive and respiratory syndrome virus, Québec reference strain

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Characterization of proteins encoded by ORFs 2 to 7 of Lelystad virus.

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A 10-kDa structural protein of porcine reproductive and respiratory syndrome virus encoded by ORF2b

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GP3 is a structural component of the PRRSV type II (US) virion.

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The genetic diversity of European type PRRSV is similar to that of the North American type but is geographically skewed within Europe

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The ever-expanding diversity of porcine reproductive and respiratory syndrome virus

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North American and European porcine reproductive and respiratory syndrome viruses differ in non-structural protein coding regions

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Definition of subtypes in the European genotype of porcine reproductive and respiratory syndrome virus: nucleocapsid characteristics and geographical distribution in Europe.

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Porcine reproductive and respiratory syndrome virus-infected alveolar macrophages contain no detectable levels of viral proteins in their plasma membrane and are protected against antibody-dependent, complement-mediated cell lysis

1 reference

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Functional impairment of PRRSV-specific peripheral CD3+CD8high cells

1 reference

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The challenge of PRRS immunology.

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Development of an experimental inactivated PRRSV vaccine that induces virus-neutralizing antibodies

1 reference

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Immune responses of pigs after experimental infection with a European strain of Porcine reproductive and respiratory syndrome virus

1 reference

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Characterization of the Humoral Immune Response to Porcine Reproductive and Respiratory Syndrome (PRRS) Virus Infection

1 reference

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Effect of cellular changes and onset of humoral immunity on the replication of porcine reproductive and respiratory syndrome virus in the lungs of pigs

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Protection against porcine reproductive and respiratory syndrome virus (PRRSV) infection through passive transfer of PRRSV-neutralizing antibodies is dose dependent.

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Role of neutralizing antibodies in PRRSV protective immunity

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Monoclonal antibody analysis of porcine reproductive and respiratory syndrome virus epitopes associated with antibody-dependent enhancement and neutralization of virus infection

1 reference

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Identification of neutralizing and nonneutralizing epitopes in the porcine reproductive and respiratory syndrome virus GP5 ectodomain.

1 reference

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The major envelope protein, GP5, of a European porcine reproductive and respiratory syndrome virus contains a neutralization epitope in its N-terminal ectodomain.

1 reference

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GP4 of porcine reproductive and respiratory syndrome virus contains a neutralizing epitope that is susceptible to immunoselection in vitro

1 reference

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Antigen-specific B-cell responses to porcine reproductive and respiratory syndrome virus infection

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Seroneutralization of porcine reproductive and respiratory syndrome virus correlates with antibody response to the GP5 major envelope glycoprotein

1 reference

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Kinetics of humoral immune response to the major structural proteins of the porcine reproductive and respiratory syndrome virus

1 reference

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Serum immune responses to the proteins of porcine reproductive and respiratory syndrome (PRRS) virus

1 reference

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Porcine B-cells recognize epitopes that are conserved between the structural proteins of American- and European-type porcine reproductive and respiratory syndrome virus

1 reference

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Emergence of porcine reproductive and respiratory syndrome virus deletion mutants: correlation with the porcine antibody response to a hypervariable site in the ORF 3 structural glycoprotein

1 reference

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Epitope mapping porcine reproductive and respiratory syndrome virus by phage display: the nsp2 fragment of the replicase polyprotein contains a cluster of B-cell epitopes

1 reference

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The primary neutralization epitope of porcine respiratory and reproductive syndrome virus strain VR-2332 is located in the middle of the GP5 ectodomain

1 reference

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Antigenic structure analysis of glycosylated protein 3 of porcine reproductive and respiratory syndrome virus

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Antigenic differences between European and American isolates of porcine reproductive and respiratory syndrome virus (PRRSV) are encoded by the carboxyterminal portion of viral open reading frame 3.

1 reference

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Serologic marker candidates identified among B-cell linear epitopes of Nsp2 and structural proteins of a North American strain of porcine reproductive and respiratory syndrome virus.

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The role of porcine reproductive and respiratory syndrome (PRRS) virus structural and non-structural proteins in virus pathogenesis

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Categorization of North American porcine reproductive and respiratory syndrome viruses: epitopic profiles of the N, M, GP5 and GP3 proteins and susceptibility to neutralization

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Immune evasion of porcine reproductive and respiratory syndrome virus through glycan shielding involves both glycoprotein 5 as well as glycoprotein 3.

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Molecular assessment of the role of envelope-associated structural proteins in cross neutralization among different PRRS viruses

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A variable region in GP4 of European-type porcine reproductive and respiratory syndrome virus induces neutralizing antibodies against homologous but not heterologous virus strains

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Respiratory tract protection upon challenge of pigs vaccinated with attenuated porcine reproductive and respiratory syndrome virus vaccines

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Porcine reproductive and respiratory syndrome virus (PRRSV)-specific mAbs: supporting diagnostics and providing new insights into the antigenic properties of the virus

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The structural biology of PRRSV

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GP4-specific neutralizing antibodies might be a driving force in PRRSV evolution

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Discriminating between serological responses to European-genotype live vaccine and European-genotype field strains of porcine reproductive and respiratory syndrome virus (PRRSV) by peptide ELISA.

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Identification of an immunodominant epitope in the C terminus of glycoprotein 5 of porcine reproductive and respiratory syndrome virus

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Monoclonal antibodies and conserved antigenic epitopes in the C terminus of GP5 protein of the North American type porcine reproductive and respiratory syndrome virus

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Monoclonal antibodies against conformationally dependent epitopes on porcine reproductive and respiratory syndrome virus

1 reference

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Monoclonal antibodies to the ORF5 product of porcine reproductive and respiratory syndrome virus define linear neutralizing determinants

1 reference

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The origin and evolution of porcine reproductive and respiratory syndrome viruses

1 reference

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Variation in open reading frames 3, 4 and 7 among porcine reproductive and respiratory syndrome virus isolates in the UK.

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A molecular clock dates the common ancestor of European-type porcine reproductive and respiratory syndrome virus at more than 10 years before the emergence of disease

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Challenges for porcine reproductive and respiratory syndrome virus (PRRSV) vaccinology

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Analysis of immunogenicity of minor envelope protein GP3 of porcine reproductive and respiratory syndrome virus in mice

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Enhanced immune responses of mice inoculated recombinant adenoviruses expressing GP5 by fusion with GP3 and/or GP4 of PRRS virus

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CD40 ligand expressed in adenovirus can improve the immunogenicity of the GP3 and GP5 of porcine reproductive and respiratory syndrome virus in swine

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HSP70 fused with GP3 and GP5 of porcine reproductive and respiratory syndrome virus enhanced the immune responses and protective efficacy against virulent PRRSV challenge in pigs

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GM-CSF fused with GP3 and GP5 of porcine reproductive and respiratory syndrome virus increased the immune responses and protective efficacy against virulent PRRSV challenge

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Baculovirus expression of proteins of porcine reproductive and respiratory syndrome virus strain Olot/91. Involvement of ORF3 and ORF5 proteins in protection.

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Construction and evaluation of genetically engineered replication-defective porcine reproductive and respiratory syndrome virus vaccine candidates

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10.1016/J.VACCINE.2011.04.071

1 reference

Europe PubMed Central

PubMed publication ID

13 December 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

13 December 2017

ResearchGate publication ID

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