(Q45367420)

13 December 2017

title

Accumulation of p62/SQSTM1 is associated with poor prognosis in patients with lung adenocarcinoma (English)

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13 December 2017

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15

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11

Hironobu Sasano

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13 December 2017

4

Yasuhiro Miki

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13 December 2017

2

Takashi Suzuki

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13 December 2017

7

Mika Watanabe

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13 December 2017

17

Masayuki Yamamoto

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13 December 2017

9

Chiaki Endo

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13 December 2017

16

Hozumi Motohashi

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13 December 2017

6

Shunichi Sugawara

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13 December 2017

Daisuke Inoue

1

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13 December 2017

Yoichiro Mitsuishi

3

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13 December 2017

Satoshi Suzuki

5

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13 December 2017

Akira Sakurada

8

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13 December 2017

Akira Uruno

10

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13 December 2017

Takayuki Nakagawa

12

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13 December 2017

Kennichi Satoh

13

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13 December 2017

Nobuyuki Tanaka

14

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13 December 2017

publication date

21 February 2012

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13 December 2017

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13 December 2017

volume

103

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13 December 2017

issue

4

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13 December 2017

page(s)

760-766

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13 December 2017

cites work

Global cancer statistics

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Dysfunctional KEAP1-NRF2 interaction in non-small-cell lung cancer

21 January 2018

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Loss of Keap1 function activates Nrf2 and provides advantages for lung cancer cell growth.

21 January 2018

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Genetic alteration of Keap1 confers constitutive Nrf2 activation and resistance to chemotherapy in gallbladder cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2012.02216.X

21 January 2018

1 reference

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Nrf2 and Keap1 abnormalities in non-small cell lung carcinoma and association with clinicopathologic features

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2012.02216.X

Oncogenic NRF2 mutations in squamous cell carcinomas of oesophagus and skin

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1349-7006.2012.02216.X

Molecular mechanisms of the Keap1–Nrf2 pathway in stress response and cancer evolution

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1349-7006.2012.02216.X

Loss of Kelch-like ECH-associated protein 1 function in prostate cancer cells causes chemoresistance and radioresistance and promotes tumor growth.

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1349-7006.2012.02216.X

Hypermethylation of the Keap1 gene in human lung cancer cell lines and lung cancer tissues

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1349-7006.2012.02216.X

RNAi-mediated silencing of nuclear factor erythroid-2-related factor 2 gene expression in non-small cell lung cancer inhibits tumor growth and increases efficacy of chemotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2012.02216.X

p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2012.02216.X

Structural basis for sorting mechanism of p62 in selective autophagy

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1349-7006.2012.02216.X

Autophagy-deficient mice develop multiple liver tumors

21 January 2018

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Persistent activation of Nrf2 through p62 in hepatocellular carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2012.02216.X

Increased signaling through p62 in the marrow microenvironment increases myeloma cell growth and osteoclast formation

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1349-7006.2012.02216.X

Mutation of the sequestosome 1 (p62) gene increases osteoclastogenesis but does not induce Paget disease

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1349-7006.2012.02216.X

Cullin3-based polyubiquitination and p62-dependent aggregation of caspase-8 mediate extrinsic apoptosis signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2012.02216.X

The atypical PKC-interacting protein p62 is an important mediator of RANK-activated osteoclastogenesis

21 January 2018

1 reference

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Mature-onset obesity and insulin resistance in mice deficient in the signaling adapter p62.

21 January 2018

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Enhanced neointimal hyperplasia and carotid artery remodelling in sequestosome 1 deficient mice.

21 January 2018

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Autophagy suppresses tumorigenesis through elimination of p62

21 January 2018

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Analysis of intracytoplasmic hyaline bodies in a hepatocellular carcinoma. Demonstration of p62 as major constituent

21 January 2018

1 reference

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p62 overexpression in breast tumors and regulation by prostate-derived Ets factor in breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2012.02216.X

Cytosolic overexpression of p62 sequestosome 1 in neoplastic prostate tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2012.02216.X

Nrf2 regulates the alternative first exons of CD36 in macrophages through specific antioxidant response elements

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2012.02216.X

Nudix-type motif 2 in human breast carcinoma: a potent prognostic factor associated with cell proliferation

21 January 2018

1 reference

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Redox cycling of 9,10-phenanthraquinone to cause oxidative stress is terminated through its monoglucuronide conjugation in human pulmonary epithelial A549 cells

21 January 2018

1 reference

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Inducible disruption of autophagy in the lung causes airway hyper-responsiveness.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2012.02216.X

Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2012.02216.X

Renal cyst formation in Fh1-deficient mice is independent of the Hif/Phd pathway: roles for fumarate in KEAP1 succination and Nrf2 signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2012.02216.X

Succination of Keap1 and activation of Nrf2-dependent antioxidant pathways in FH-deficient papillary renal cell carcinoma type 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2012.02216.X

Direct interaction between Nrf2 and p21(Cip1/WAF1) upregulates the Nrf2-mediated antioxidant response

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2012.02216.X

Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2012.02216.X

The ubiquitin-binding protein p62 is expressed in breast cancers showing features of aggressive disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2012.02216.X

Signal integration and diversification through the p62 scaffold protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2012.02216.X

PB1 domain interaction of p62/sequestosome 1 and MEKK3 regulates NF-kappaB activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2012.02216.X

Molecular characteristics of liver metastases from uveal melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2012.02216.X

The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22320446

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The diversity expression of p62 in digestive system cancers

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22320446

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The Keap1-Nrf2 system as an in vivo sensor for electrophiles

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22320446

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1111/J.1349-7006.2012.02216.X

1 reference

13 December 2017

0 references

1 reference