(Q45398491)

14 December 2017

title

Identification of host range mutants of myxoma virus with altered oncolytic potential in human glioma cells (English)

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14 December 2017

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myxoma virus

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4

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14 December 2017

10

Grant McFadden

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14 December 2017

John W Barrett

1

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14 December 2017

Lindsay R Alston

2

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14 December 2017

Fuan Wang

3

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14 December 2017

Philippe-Alexandre Gilbert

5

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14 December 2017

Xiujuan Gao

6

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14 December 2017

June Jimenez

7

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14 December 2017

Danielle Villeneuve

8

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14 December 2017

Peter Forsyth

9

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14 December 2017

language of work or name

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1 December 2007

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14 December 2017

published in

Journal of NeuroVirology

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14 December 2017

volume

13

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14 December 2017

issue

6

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14 December 2017

page(s)

549-560

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Oncolytic vesicular stomatitis virus induces apoptosis via signaling through PKR, Fas, and Daxx

14 December 2017

cites work

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12 December 2020

The myxoma virus M-T4 gene encodes a novel RDEL-containing protein that is retained within the endoplasmic reticulum and is important for the productive infection of lymphocytes

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12 December 2020

Post-translational modification of the myxoma-virus anti-inflammatory serpin SERP-1 by a virally encoded sialyltransferase

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12 December 2020

Infection of human cancer cells with myxoma virus requires Akt activation via interaction with a viral ankyrin-repeat host range factor.

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12 December 2020

Molecular determinants of the response of glioblastomas to EGFR kinase inhibitors.

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12 December 2020

Genetic alteration and expression of the phosphoinositol-3-kinase/Akt pathway genes PIK3CA and PIKE in human glioblastomas

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12 December 2020

Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers

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12 December 2020

Deletion analysis of two tandemly arranged virulence genes in myxoma virus, M11L and myxoma growth factor

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12 December 2020

M-T5, the ankyrin repeat, host range protein of myxoma virus, activates Akt and can be functionally replaced by cellular PIKE-A

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12 December 2020

Clonogenic assay of cells in vitro.

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12 December 2020

Gene therapy and targeted toxins for glioma

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12 December 2020

SERP1, a serine proteinase inhibitor encoded by myxoma virus, is a secreted glycoprotein that interferes with inflammation

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12 December 2020

Role of the C-terminal RDEL motif of the myxoma virus M-T4 protein in terms of apoptosis regulation and viral pathogenesis

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12 December 2020

PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer

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12 December 2020

Myxoma virus M063R is a host range gene essential for virus replication in rabbit cells

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12 December 2020

VSV strains with defects in their ability to shutdown innate immunity are potent systemic anti-cancer agents

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12 December 2020

Targeting human glioblastoma cells: comparison of nine viruses with oncolytic potential

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12 December 2020

Clinical trial results with oncolytic virotherapy: a century of promise, a decade of progress

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12 December 2020

M135R is a novel cell surface virulence factor of myxoma virus

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12 December 2020

Distinct domains of M-T2, the myxoma virus tumor necrosis factor (TNF) receptor homolog, mediate extracellular TNF binding and intracellular apoptosis inhibition.

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12 December 2020

Naturally oncolytic viruses.

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12 December 2020

Altered molecular pathways in gliomas: an overview of clinically relevant issues

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12 December 2020

Advances in oncolytic viral therapy

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12 December 2020

Encoding of a homolog of the IFN-gamma receptor by myxoma virus

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12 December 2020

Expression of the myxoma virus tumor necrosis factor receptor homologue and M11L genes is required to prevent virus-induced apoptosis in infected rabbit T lymphocytes

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12 December 2020

Myxoma virus is a novel oncolytic virus with significant antitumor activity against experimental human gliomas

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12 December 2020

Recent progress in the battle between oncolytic viruses and tumours

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12 December 2020

Frequent co-alterations of TP53, p16/CDKN2A, p14ARF, PTEN tumor suppressor genes in human glioma cell lines

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12 December 2020

Oncolytic virotherapy synergism with signaling inhibitors: Rapamycin increases myxoma virus tropism for human tumor cells

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12 December 2020

Technical knockout: understanding poxvirus pathogenesis by selectively deleting viral immunomodulatory genes

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12 December 2020

Genetic markers in glioblastoma: prognostic significance and future therapeutic implications

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12 December 2020

Variable deficiencies in the interferon response enhance susceptibility to vesicular stomatitis virus oncolytic actions in glioblastoma cells but not in normal human glial cells

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12 December 2020

Disruption of M-T5, a novel myxoma virus gene member of poxvirus host range superfamily, results in dramatic attenuation of myxomatosis in infected European rabbits

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12 December 2020

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12 December 2020

Myxoma virus expresses a secreted protein with homology to the tumor necrosis factor receptor gene family that contributes to viral virulence

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12 December 2020

Systemic efficacy with oncolytic virus therapeutics: clinical proof-of-concept and future directions.

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12 December 2020

10.1080/13550280701591526

Identifiers

DOI

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Dimensions Publication ID

14 December 2017

1015032732

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