(Q45399384)

14 December 2017

title

Ligand-independent FLT3 activation does not cooperate with MLL-AF4 to immortalize/transform cord blood CD34+ cells (English)

1 reference

14 December 2017

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24240202%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Rolf Marschalek

10

1 reference

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7 June 2020

Pablo Menendez

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24240202%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Verónica Ayllón

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24240202%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Cristina Prieto

3

1 reference

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7 June 2020

M. Carmen Chillón

9

1 reference

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7 June 2020

author name string

R Montes

1

1 reference

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7 June 2020

A Bursen

4

1 reference

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7 June 2020

C Prelle

5

1 reference

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7 June 2020

D Romero-Moya

6

1 reference

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7 June 2020

O Navarro-Montero

8

1 reference

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7 June 2020

C Bueno

11

1 reference

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7 June 2020

language of work or name

1 reference

18 November 2013

1 reference

14 December 2017

number of pages

9

1 reference

inferred from page(s)

published in

Leukemia

1 reference

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7 June 2020

volume

28

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7 June 2020

issue

3

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7 June 2020

page(s)

666-674

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https://scigraph.springernature.com/pub.10.1038/leu.2013.346

7 June 2020

exact match

0 references

cites work

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Insights into the cellular origin and etiology of the infant pro-B acute lymphoblastic leukemia with MLL-AF4 rearrangement

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In utero rearrangements in the trithorax-related oncogene in infant leukaemias.

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Leukemia in twins: lessons in natural history

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Mechanisms of leukemogenesis by MLL fusion proteins

21 January 2018

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The AF4.MLL fusion protein is capable of inducing ALL in mice without requirement of MLL.AF4.

21 January 2018

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A murine Mll-AF4 knock-in model results in lymphoid and myeloid deregulation and hematologic malignancy

21 January 2018

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H3K79 methylation profiles define murine and human MLL-AF4 leukemias

21 January 2018

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Enforced expression of MLL-AF4 fusion in cord blood CD34+ cells enhances the hematopoietic repopulating cell function and clonogenic potential but is not sufficient to initiate leukemia.

21 January 2018

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A human ESC model for MLL-AF4 leukemic fusion gene reveals an impaired early hematopoietic-endothelial specification

21 January 2018

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FLT3 mutations in childhood acute lymphoblastic leukemia

21 January 2018

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FLT3 mutations in the activation loop of tyrosine kinase domain are frequently found in infant ALL with MLL rearrangements and pediatric ALL with hyperdiploidy

21 January 2018

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Multistep pathogenesis of leukemia via the MLL-AF4 chimeric gene/Flt3 gene tyrosine kinase domain (TKD) mutation-related enhancement of S100A6 expression

21 January 2018

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Prognostic significance of FLT3 mutational status and expression levels in MLL-AF4+ and MLL-germline acute lymphoblastic leukemia.

21 January 2018

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Aberrant chromatin at genes encoding stem cell regulators in human mixed-lineage leukemia

21 January 2018

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D-HPLC analysis of the entire FLT3 gene in MLL rearranged and hyperdiploid acute lymphoblastic leukemia.

21 January 2018

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Prognostic significance of high-level FLT3 expression in MLL-rearranged infant acute lymphoblastic leukemia.

21 January 2018

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FLT3 activation cooperates with MLL-AF4 fusion protein to abrogate the hematopoietic specification of human ESCs

21 January 2018

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Etoposide induces MLL rearrangements and other chromosomal abnormalities in human embryonic stem cells.

21 January 2018

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SCL/TAL1 regulates hematopoietic specification from human embryonic stem cells

21 January 2018

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Human induced pluripotent stem cells develop teratoma more efficiently and faster than human embryonic stem cells regardless the site of injection

21 January 2018

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Cord blood-derived CD34+ hematopoietic cells with low mitochondrial mass are enriched in hematopoietic repopulating stem cell function.

21 January 2018

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The ROCK inhibitor Y-27632 negatively affects the expansion/survival of both fresh and cryopreserved cord blood-derived CD34+ hematopoietic progenitor cells: Y-27632 negatively affects the expansion/survival of CD34+HSPCs.

21 January 2018

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OP9 stroma augments survival of hematopoietic precursors and progenitors during hematopoietic differentiation from human embryonic stem cells

21 January 2018

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Genetic stability of human embryonic stem cells: A first-step toward the development of potential hESC-based systems for modeling childhood leukemia.

21 January 2018

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Clinical relevance of FLT3 gene abnormalities in Brazilian patients with infant leukemia.

21 January 2018

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Implementation of array based whole-genome high-resolution technologies confirms the absence of secondary copy-number alterations in MLL-AF4-positive infant ALL patients.

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21 January 2018

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21 January 2018

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Leukemic transformation by the MLL-AF6 fusion oncogene requires the H3K79 methyltransferase Dot1l

21 January 2018

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Specific promoter methylation identifies different subgroups of MLL-rearranged infant acute lymphoblastic leukemia, influences clinical outcome, and provides therapeutic options

21 January 2018

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Absence of global hypomethylation in promoter hypermethylated Mixed Lineage Leukaemia-rearranged infant acute lymphoblastic leukaemia.

21 January 2018

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A conditional model of MLL-AF4 B-cell tumourigenesis using invertor technology

21 January 2018

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NG2 antigen is expressed in CD34+ HPCs and plasmacytoid dendritic cell precursors: is NG2 expression in leukemia dependent on the target cell where leukemogenesis is triggered?

21 January 2018

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12 December 2020

Intrahepatic transplantation of cord blood CD34+ cells into newborn NOD/SCID-IL2Rγ(null) mice allows efficient multi-organ and multi-lineage hematopoietic engraftment without accessory cells

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12 December 2020

Infant leukaemia biology, aetiology and treatment

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12 December 2020

Intra-bone marrow transplantation of human CD34(+) cells into NOD/LtSz-scid IL-2rgamma(null) mice permits multilineage engraftment without previous irradiation

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12 December 2020

Clinical characteristics and treatment outcome of childhood acute lymphoblastic leukemia with the t(4;11)(q21;q23): a collaborative study of 40 cases

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12 December 2020

The composition of leukapheresis products impacts on the hematopoietic recovery after autologous transplantation independently of the mobilization regimen

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12 December 2020

Quantitative analysis of bcl-2 expression in normal and leukemic human B-cell differentiation

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12 December 2020

DNA copy-number abnormalities do not occur in infant ALL with t(4;11)/MLL-AF4

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12 December 2020

Defects in yolk sac hematopoiesis in Mll-null embryos.

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12 December 2020

Intra-bone marrow transplantation facilitates pauci-clonal human hematopoietic repopulation of NOD/SCID/beta2m(-/-) mice

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12 December 2020

Identifiers

DOI

10.1038/LEU.2013.346

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24240202%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

7 June 2020

1048028002

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24240202%20AND%20SRC:MED&resulttype=core&format=json