(Q45413895)

English

Transcriptional activity of blood-and cerebrospinal fluid-derived nef/long-terminal repeat sequences isolated from a slow progressor infected with nef-deleted human immunodeficiency virus type 1 (HIV-1) who developed HIV-associated dementia

scientific article published in June 2006

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Europe PubMed Central

PubMed publication ID

14 December 2017

Transcriptional activity of blood-and cerebrospinal fluid-derived nef/long-terminal repeat sequences isolated from a slow progressor infected with nef-deleted human immunodeficiency virus type 1 (HIV-1) who developed HIV-associated dementia (English)

1 reference

Europe PubMed Central

PubMed publication ID

14 December 2017

cerebrospinal fluid

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4

1 reference

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14 December 2017

object named as

Bruce J Brew

9

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Steven L Wesselingh

8

object named as

Steven L Wesselingh

1 reference

Europe PubMed Central

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14 December 2017

author name string

Melissa J Churchill

1

1 reference

Europe PubMed Central

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14 December 2017

Anna Figueiredo

2

1 reference

Europe PubMed Central

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14 December 2017

Daniel Cowley

3

1 reference

Europe PubMed Central

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14 December 2017

Damian Fj Purcell

5

1 reference

Europe PubMed Central

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14 December 2017

John S Sullivan

6

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Europe PubMed Central

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14 December 2017

Dale A McPhee

7

1 reference

Europe PubMed Central

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14 December 2017

Paul R Gorry

10

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Europe PubMed Central

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14 December 2017

publication date

1 June 2006

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Europe PubMed Central

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14 December 2017

Journal of NeuroVirology

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Europe PubMed Central

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14 December 2017

12

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Europe PubMed Central

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14 December 2017

3

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14 December 2017

219-228

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14 December 2017

The human immunodeficiency virus-1 nef gene product: a positive factor for viral infection and replication in primary lymphocytes and macrophages

1 reference

https://pubmed.ncbi.nlm.nih.gov/16877303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Independent evolution of human immunodeficiency virus (HIV) drug resistance mutations in diverse areas of the brain in HIV-infected patients, with and without dementia, on antiretroviral treatment

1 reference

https://pubmed.ncbi.nlm.nih.gov/16877303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic composition of human immunodeficiency virus type 1 in cerebrospinal fluid and blood without treatment and during failing antiretroviral therapy.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16877303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The neuropathogenesis of AIDS

1 reference

https://pubmed.ncbi.nlm.nih.gov/16877303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Determinants of syncytium formation in microglia by human immunodeficiency virus type 1: role of the V1/V2 domains

1 reference

https://pubmed.ncbi.nlm.nih.gov/16877303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vivo replication kinetics of a nef-deleted strain of HIV-1

1 reference

https://pubmed.ncbi.nlm.nih.gov/16877303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Brief report: absence of intact nef sequences in a long-term survivor with nonprogressive HIV-1 infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/16877303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interaction with CD4 and antibodies to CD4-induced epitopes of the envelope gp120 from a microglial cell-adapted human immunodeficiency virus type 1 isolate

1 reference

https://pubmed.ncbi.nlm.nih.gov/16877303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Both virus and host components are important for the manifestation of a Nef- phenotype in HIV-1 and HIV-2.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16877303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High frequency of defective nef alleles in a long-term survivor with nonprogressive human immunodeficiency virus type 1 infection.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16877303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intracerebral cytokine messenger RNA expression in acquired immunodeficiency syndrome dementia

1 reference

https://pubmed.ncbi.nlm.nih.gov/16877303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunologic and virologic status after 14 to 18 years of infection with an attenuated strain of HIV-1. A report from the Sydney Blood Bank Cohort

1 reference

https://pubmed.ncbi.nlm.nih.gov/16877303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanisms of HIV-1 neurotropism

1 reference

https://pubmed.ncbi.nlm.nih.gov/16877303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HIV-1 LTR C/EBP binding site sequence configurations preferentially encountered in brain lead to enhanced C/EBP factor binding and increased LTR-specific activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/16877303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Restricted HIV-1 infection of human astrocytes: potential role of nef in the regulation of virus replication.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16877303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Microglia express CCR5, CXCR4, and CCR3, but of these, CCR5 is the principal coreceptor for human immunodeficiency virus type 1 dementia isolates.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16877303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Live attenuated, nef-deleted SIV is pathogenic in most adult macaques after prolonged observation

1 reference

https://pubmed.ncbi.nlm.nih.gov/16877303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Persistent CCR5 utilization and enhanced macrophage tropism by primary blood human immunodeficiency virus type 1 isolates from advanced stages of disease and comparison to tissue-derived isolates

1 reference

https://pubmed.ncbi.nlm.nih.gov/16877303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of three nef-defective human immunodeficiency virus type 1 strains associated with long-term nonprogression. Australian Long-Term Nonprogressor Study Group

1 reference

https://pubmed.ncbi.nlm.nih.gov/16877303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of highly attenuated mutants of simian immunodeficiency virus

1 reference

https://pubmed.ncbi.nlm.nih.gov/16877303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of attenuated variants of HIV-1 circulating recombinant form 01_AE that are associated with slow disease progression due to gross genetic alterations in the nef/long terminal repeat sequences

1 reference

https://pubmed.ncbi.nlm.nih.gov/16877303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biological analysis of human immunodeficiency virus type 1 R5 envelopes amplified from brain and lymph node tissues of AIDS patients with neuropathology reveals two distinct tropism phenotypes and identifies envelopes in the brain that confer an enh

1 reference

https://pubmed.ncbi.nlm.nih.gov/16877303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Macrophage tropism of human immunodeficiency virus type 1 isolates from brain and lymphoid tissues predicts neurotropism independent of coreceptor specificity

1 reference

https://pubmed.ncbi.nlm.nih.gov/16877303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HIV-1 tropism for the central nervous system: Brain-derived envelope glycoproteins with lower CD4 dependence and reduced sensitivity to a fusion inhibitor

1 reference

https://pubmed.ncbi.nlm.nih.gov/16877303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Region-specific distribution of human immunodeficiency virus type 1 long terminal repeats containing specific configurations of CCAAT/enhancer-binding protein site II in brains derived from demented and nondemented patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/16877303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Determinants of increased replicative capacity of serially passaged simian immunodeficiency virus with nef deleted in rhesus monkeys

1 reference

https://pubmed.ncbi.nlm.nih.gov/16877303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interaction between CCAAT/enhancer binding protein and cyclic AMP response element binding protein 1 regulates human immunodeficiency virus type 1 transcription in cells of the monocyte/macrophage lineage.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16877303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CCR3 and CCR5 are co-receptors for HIV-1 infection of microglia

1 reference

https://pubmed.ncbi.nlm.nih.gov/16877303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Demented and nondemented patients with AIDS differ in brain-derived human immunodeficiency virus type 1 envelope sequences

1 reference

https://pubmed.ncbi.nlm.nih.gov/16877303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional interactions between C/EBP, Sp1, and COUP-TF regulate human immunodeficiency virus type 1 gene transcription in human brain cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/16877303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Long-term symptomless HIV-1 infection in recipients of blood products from a single donor

1 reference

https://pubmed.ncbi.nlm.nih.gov/16877303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structural and functional evolution of human immunodeficiency virus type 1 long terminal repeat CCAAT/enhancer binding protein sites and their use as molecular markers for central nervous system disease progression

1 reference

https://pubmed.ncbi.nlm.nih.gov/16877303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased CCR5 affinity and reduced CCR5/CD4 dependence of a neurovirulent primary human immunodeficiency virus type 1 isolate.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16877303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chemokine receptor utilization by human immunodeficiency virus type 1 isolates that replicate in microglia

1 reference

https://pubmed.ncbi.nlm.nih.gov/16877303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The decreased replicative capacity of simian immunodeficiency virus SIVmac239Delta(nef) is manifest in cultures of immature dendritic cellsand T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/16877303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Importance of the nef gene for maintenance of high virus loads and for development of AIDS

1 reference

https://pubmed.ncbi.nlm.nih.gov/16877303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Longitudinal analysis of human immunodeficiency virus type 1 nef/long terminal repeat sequences in a cohort of long-term survivors infected from a single source

1 reference

https://pubmed.ncbi.nlm.nih.gov/16877303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Uncoupling coreceptor usage of human immunodeficiency virus type 1 (HIV-1) from macrophage tropism reveals biological properties of CCR5-restricted HIV-1 isolates from patients with acquired immunodeficiency syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/16877303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High-affinity interaction between HIV-1 Vpr and specific sequences that span the C/EBP and adjacent NF-kappaB sites within the HIV-1 LTR correlate with HIV-1-associated dementia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16877303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Varied tropism of HIV-1 isolates derived from different regions of adult brain cortex discriminate between patients with and without AIDS dementia complex (ADC): evidence for neurotropic HIV variants

1 reference

https://pubmed.ncbi.nlm.nih.gov/16877303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Disrupting surfaces of nef required for downregulation of CD4 and for enhancement of virion infectivity attenuates simian immunodeficiency virus replication in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/16877303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pathogenic and nef-interrupted simian-human immunodeficiency viruses traffic to the macaque CNS and cause astrocytosis early after inoculation

1 reference

https://pubmed.ncbi.nlm.nih.gov/16877303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pathogenesis of simian immunodeficiency virus encephalitis: viral determinants of neurovirulence

1 reference

https://pubmed.ncbi.nlm.nih.gov/16877303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutational trends in V3 loop protein sequences observed in different genetic lineages of human immunodeficiency virus type 1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16877303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genomic structure of an attenuated quasi species of HIV-1 from a blood transfusion donor and recipients

1 reference

https://pubmed.ncbi.nlm.nih.gov/16877303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HIV-associated cognitive impairment before and after the advent of combination therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/16877303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chemokine receptors and mechanisms of cell death in HIV neuropathogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16877303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Simian immunodeficiency virus SIVmac chimeric virus whose env gene was derived from SIV-encephalitic brain is macrophage-tropic but not neurovirulent.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16877303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HIV-1 tropism for mononuclear phagocytes can be determined by regions of gp120 outside the CD4-binding domain

1 reference

https://pubmed.ncbi.nlm.nih.gov/16877303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human immunodeficiency virus type 1 genetic diversity in the nervous system: evolutionary epiphenomenon or disease determinant?

1 reference

https://pubmed.ncbi.nlm.nih.gov/16877303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional differences between the long terminal repeat transcriptional promoters of human immunodeficiency virus type 1 subtypes A through G.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16877303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic and functional analysis of full-length human immunodeficiency virus type 1 env genes derived from brain and blood of patients with AIDS.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16877303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Complete nucleotide sequence, genome organization, and biological properties of human immunodeficiency virus type 1 in vivo: evidence for limited defectiveness and complementation

1 reference

https://pubmed.ncbi.nlm.nih.gov/16877303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Limited viral spread and rapid immune response in lymph nodes of macaques inoculated with attenuated simian immunodeficiency virus

1 reference

https://pubmed.ncbi.nlm.nih.gov/16877303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular characterization of human immunodeficiency virus type 1 cloned directly from uncultured human brain tissue: identification of replication-competent and -defective viral genomes

1 reference

https://pubmed.ncbi.nlm.nih.gov/16877303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Decreased neurotropism of nef long terminal repeat (nef/LTR)-deleted simian immunodeficiency virus

1 reference

https://pubmed.ncbi.nlm.nih.gov/16877303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sp1 and related factors fail to interact with the NF-kappaB-proximal G/C box in the LTR of a replication competent, brain-derived strain of HIV-1 (YU-2).

1 reference

https://pubmed.ncbi.nlm.nih.gov/16877303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Longitudinal Analysis ofnef/Long Terminal Repeat–Deleted HIV‐1 in Blood and Cerebrospinal Fluid of a Long‐Term Survivor Who Developed HIV‐Associated Dementia

1 reference

https://pubmed.ncbi.nlm.nih.gov/16877303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.1080/13550280600827369

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Europe PubMed Central

PubMed publication ID

14 December 2017

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PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

14 December 2017

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