(Q45417025)

English

The TLR4 agonist, monophosphoryl lipid A, attenuates the cytokine storm associated with respiratory syncytial virus vaccine-enhanced disease.

scientific article published on 18 April 2006

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20 January 2020

The TLR4 agonist, monophosphoryl lipid A, attenuates the cytokine storm associated with respiratory syncytial virus vaccine-enhanced disease (English)

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20 January 2020

toll-like receptor

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6

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20 January 2020

Marina Boukhvalova

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Marina S Boukhvalova

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20 January 2020

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Gregory A Prince

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20 January 2020

Stefanie N. Vogel

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Stefanie N Vogel

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20 January 2020

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Layla Soroush

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20 January 2020

Dolores C Harrigan

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20 January 2020

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18 April 2006

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20 January 2020

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20 January 2020

5027-5035

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20 January 2020

Bronchiolitis-associated mortality and estimates of respiratory syncytial virus-associated deaths among US children, 1979-1997.

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2006.03.064

7 January 2021

Respiratory syncytial virus and other pneumoviruses: a review of the international symposium--RSV 2003.

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2006.03.064

7 January 2021

Absence of lung immunopathology following respiratory syncytial virus (RSV) challenge in mice immunized with a recombinant RSV G protein fragment

1 reference

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7 January 2021

Efficacy and safety studies of a recombinant chimeric respiratory syncytial virus FG glycoprotein vaccine in cotton rats

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2006.03.064

7 January 2021

Adjuvants influence the quantitative and qualitative immune response in BALB/c mice immunized with respiratory syncytial virus FG subunit vaccine

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2006.03.064

7 January 2021

Immunoprotective activity and safety of a respiratory syncytial virus vaccine: mucosal delivery of fusion glycoprotein with a CpG oligodeoxynucleotide adjuvant

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2006.03.064

7 January 2021

Lipid A and immunotherapy.

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2006.03.064

7 January 2021

Monophosphoryl lipid A adjuvant reverses a principal histologic parameter of formalin-inactivated respiratory syncytial virus vaccine-induced disease

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2006.03.064

7 January 2021

Enhancement of antigen-specific immunity via the TLR4 ligands MPL adjuvant and Ribi.529.

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2006.03.064

7 January 2021

Taking toll: lipid A mimetics as adjuvants and immunomodulators

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2006.03.064

7 January 2021

Role of Innate Immune Factors in the Adjuvant Activity of Monophosphoryl Lipid A

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2006.03.064

7 January 2021

Cell activation by Porphyromonas gingivalis lipid A molecule through Toll-like receptor 4- and myeloid differentiation factor 88-dependent signaling pathway

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2006.03.064

7 January 2021

Pattern recognition receptors TLR4 and CD14 mediate response to respiratory syncytial virus

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2006.03.064

7 January 2021

Association between common Toll-like receptor 4 mutations and severe respiratory syncytial virus disease

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2006.03.064

7 January 2021

Involvement of toll-like receptor 4 in innate immunity to respiratory syncytial virus

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2006.03.064

7 January 2021

Respiratory syncytial virus-induced activation of nuclear factor-kappaB in the lung involves alveolar macrophages and toll-like receptor 4-dependent pathways

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2006.03.064

7 January 2021

Immune responses and disease enhancement during respiratory syncytial virus infection

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2006.03.064

7 January 2021

Respiratory syncytial virus disease in infants despite prior administration of antigenic inactivated vaccine

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2006.03.064

7 January 2021

Vaccine-enhanced respiratory syncytial virus disease in cotton rats following immunization with Lot 100 or a newly prepared reference vaccine

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2006.03.064

7 January 2021

Cytokine and chemokine gene expression after primary and secondary respiratory syncytial virus infection in cotton rats

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2006.03.064

7 January 2021

Stabilization of respiratory syncytial virus (RSV) against thermal inactivation and freeze-thaw cycles for development and control of RSV vaccines and immune globulin

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2006.03.064

7 January 2021

The cotton rat: an underutilized animal model for human infectious diseases can now be exploited using specific reagents to cytokines, chemokines, and interferons.

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2006.03.064

7 January 2021

New insights into the role of cytokines in asthma

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2006.03.064

7 January 2021

Interleukin 9: a candidate gene for asthma

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2006.03.064

7 January 2021

Molecular analysis of human interleukin-9 receptor transcripts in peripheral blood mononuclear cells. Identification of a splice variant encoding for a nonfunctional cell surface receptor

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2006.03.064

7 January 2021

Interleukin 9 production in the lungs of infants with severe respiratory syncytial virus bronchiolitis

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2006.03.064

7 January 2021

Monophosphoryl lipid A (MPL) upregulates major histocompatibility complex (MHC) class I expression by increasing interferon-gamma (IFN-gamma)

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2006.03.064

7 January 2021

Monophosphoryl lipid A (MPL) promotes allergen-induced immune deviation in favour of Th1 responses.

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2006.03.064

7 January 2021

Adjuvants recognized by toll-like receptors inhibit the induction of polarized type 2 T cell responses by natural attachment (G) protein of respiratory syncytial virus

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2006.03.064

7 January 2021

The adjuvant combination monophosphoryl lipid A and QS21 switches T cell responses induced with a soluble recombinant HIV protein from Th2 to Th1

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2006.03.064

7 January 2021

Pretreatment of normal humans with monophosphoryl lipid A induces tolerance to endotoxin: a prospective, double-blind, randomized, controlled trial.

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2006.03.064

7 January 2021

Both immunisation with a formalin-inactivated respiratory syncytial virus (RSV) vaccine and a mock antigen vaccine induce severe lung pathology and a Th2 cytokine profile in RSV-challenged mice

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2006.03.064

7 January 2021

Immune response to experimentally induced infection with respiratory syncytial virus: possible role in the development of pulmonary disease

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2006.03.064

7 January 2021

A well-tolerated grass pollen-specific allergy vaccine containing a novel adjuvant, monophosphoryl lipid A, reduces allergic symptoms after only four preseasonal injections

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2006.03.064

7 January 2021

Allergen-specific immunotherapy with a monophosphoryl lipid A-adjuvanted vaccine: reduced seasonally boosted immunoglobulin E production and inhibition of basophil histamine release by therapy-induced blocking antibodies.

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2006.03.064

7 January 2021

Monophosphoryl lipid A activates both human dendritic cells and T cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2006.03.064

7 January 2021

Mechanisms of monophosphoryl lipid A augmentation of host responses to recombinant HagB from Porphyromonas gingivalis

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2006.03.064

7 January 2021

Pulmonary histopathology induced by respiratory syncytial virus (RSV) challenge of formalin-inactivated RSV-immunized BALB/c mice is abrogated by depletion of CD4+ T cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2006.03.064

7 January 2021

based on heuristic

inferred from DOI database lookup

Generation of atypical pulmonary inflammatory responses in BALB/c mice after immunization with the native attachment (G) glycoprotein of respiratory syncytial virus

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2006.03.064

7 January 2021

based on heuristic

inferred from DOI database lookup

Enhancement of respiratory syncytial virus pulmonary pathology in cotton rats by prior intramuscular inoculation of formalin-inactiva ted virus

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2006.03.064

7 January 2021

based on heuristic

inferred from DOI database lookup

Early-phase endotoxin tolerance: induction by a detoxified lipid A derivative, monophosphoryl lipid A.

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2006.03.064

7 January 2021

based on heuristic

inferred from DOI database lookup

Effect of monophosphoryl lipid A on host resistance to bacterial infection

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2006.03.064

7 January 2021

based on heuristic

inferred from DOI database lookup

Pulmonary and hepatic gene expression following cecal ligation and puncture: monophosphoryl lipid A prophylaxis attenuates sepsis-induced cytokine and chemokine expression and neutrophil infiltration

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2006.03.064

7 January 2021

based on heuristic

inferred from DOI database lookup

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