(Q45418238)

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Immunogenicity and safety of a novel therapeutic hepatitis C virus (HCV) peptide vaccine: a randomized, placebo controlled trial for dose optimization in 128 healthy subjects.

scientific article published on 20 March 2006

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Europe PubMed Central

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18 January 2020

Immunogenicity and safety of a novel therapeutic hepatitis C virus (HCV) peptide vaccine: a randomized, placebo controlled trial for dose optimization in 128 healthy subjects (English)

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18 January 2020

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based on heuristic

inferred from title

Hepatitis C virus

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based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

3

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18 January 2020

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Christa Firbas

1

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18 January 2020

Bernd Jilma

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18 January 2020

Vera Buerger

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18 January 2020

Sandra Jelovcan

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18 January 2020

Karen Lingnau

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18 January 2020

Michael Buschle

7

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18 January 2020

Jürgen Frisch

8

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18 January 2020

Christoph S Klade

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18 January 2020

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20 March 2006

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18 January 2020

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18 January 2020

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18 January 2020

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18 January 2020

4343-4353

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18 January 2020

Epidemiology of hepatitis C

1 reference

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7 January 2021

Peginterferon alfa-2b plus ribavirin compared with interferon alfa-2b plus ribavirin for initial treatment of chronic hepatitis C: a randomised trial

1 reference

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7 January 2021

Correlation between virus genotype and chronicity rate in acute hepatitis C.

1 reference

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7 January 2021

Cell-mediated immunity and the outcome of hepatitis C virus infection

1 reference

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7 January 2021

The role of hepatitis C virus specific CD4+ T lymphocytes in acute and chronic hepatitis C.

1 reference

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7 January 2021

Different clinical behaviors of acute hepatitis C virus infection are associated with different vigor of the anti-viral cell-mediated immune response

1 reference

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7 January 2021

Analysis of a successful immune response against hepatitis C virus

1 reference

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7 January 2021

Recurrence of hepatitis C virus after loss of virus-specific CD4(+) T-cell response in acute hepatitis C

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2006.03.009

7 January 2021

Conserved hepatitis C virus sequences are highly immunogenic for CD4(+) T cells: implications for vaccine development.

1 reference

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7 January 2021

Association of hepatitis C virus-specific CD8+ T cells with viral clearance in acute hepatitis C.

1 reference

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7 January 2021

Analysis of successful immune responses in persons infected with hepatitis C virus

1 reference

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7 January 2021

CD8+ T lymphocyte responses are induced during acute hepatitis C virus infection but are not sustained

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2006.03.009

7 January 2021

HCV Persistence and Immune Evasion in the Absence of Memory T Cell Help

1 reference

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7 January 2021

Kinetics of CD4+ and CD8+ Memory T-Cell Responses during Hepatitis C Virus Rechallenge of Previously Recovered Chimpanzees

1 reference

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7 January 2021

Comprehensive analyses of CD8+ T cell responses during longitudinal study of acute human hepatitis C.

1 reference

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7 January 2021

Cellular immune responses persist and humoral responses decrease two decades after recovery from a single-source outbreak of hepatitis C

1 reference

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7 January 2021

Comprehensive Analysis of CD8+-T-Cell Responses against Hepatitis C Virus Reveals Multiple Unpredicted Specificities

1 reference

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7 January 2021

Broad Specificity of Virus-Specific CD4+ T-Helper-Cell Responses in Resolved Hepatitis C Virus Infection

1 reference

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7 January 2021

Novel CD4+ and CD8+ T-cell determinants within the NS3 protein in subjects with spontaneously resolved HCV infection

1 reference

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7 January 2021

High resolution analysis of cellular immune responses in resolved and persistent hepatitis C virus infection

1 reference

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7 January 2021

Sustained Dysfunction of Antiviral CD8+ T Lymphocytes after Infection with Hepatitis C Virus

1 reference

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7 January 2021

Impaired effector function of hepatitis C virus-specific CD8+ T cells in chronic hepatitis C virus infection

1 reference

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7 January 2021

Mutational escape from CD8+ T cell immunity: HCV evolution, from chimpanzees to man

1 reference

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7 January 2021

Immunological significance of cytotoxic T lymphocyte epitope variants in patients chronically infected by the hepatitis C virus

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2006.03.009

7 January 2021

The outcome of hepatitis C virus infection is predicted by escape mutations in epitopes targeted by cytotoxic T lymphocytes

1 reference

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7 January 2021

Hepatitis C virus mutation affects proteasomal epitope processing

1 reference

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7 January 2021

CD8 Epitope Escape and Reversion in Acute HCV Infection

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2006.03.009

7 January 2021

Escape mutations alter proteasome processing of major histocompatibility complex class I-restricted epitopes in persistent hepatitis C virus infection

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2006.03.009

7 January 2021

Immune evasion versus recovery after acute hepatitis C virus infection from a shared source

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2006.03.009

7 January 2021

Cellular immune selection with hepatitis C virus persistence in humans

1 reference

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7 January 2021

Impaired allostimulatory function of dendritic cells in chronic hepatitis C infection

1 reference

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7 January 2021

Reduced numbers and impaired ability of myeloid and plasmacytoid dendritic cells to polarize T helper cells in chronic hepatitis C virus infection

1 reference

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7 January 2021

Comparable functions of plasmacytoid and monocyte-derived dendritic cells in chronic hepatitis C patients and healthy donors

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2006.03.009

7 January 2021

Normal functional capacity in circulating myeloid and plasmacytoid dendritic cells in patients with chronic hepatitis C

1 reference

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7 January 2021

Subversion of effector CD8+ T cell differentiation in acute hepatitis C virus infection: exploring the immunological mechanisms

1 reference

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7 January 2021

Subversion of effector CD8+ T cell differentiation in acute hepatitis C virus infection: the role of the virus.

1 reference

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7 January 2021

An immunomodulatory role for CD4(+)CD25(+) regulatory T lymphocytes in hepatitis C virus infection.

1 reference

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7 January 2021

Regulatory T cells suppress in vitro proliferation of virus-specific CD8+ T cells during persistent hepatitis C virus infection

1 reference

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7 January 2021

T cells with a CD4+CD25+ regulatory phenotype suppress in vitro proliferation of virus-specific CD8+ T cells during chronic hepatitis C virus infection.

1 reference

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7 January 2021

Prevention of hepatitis C virus infection in chimpanzees after antibody-mediated in vitro neutralization

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7 January 2021

Hepatitis C virus: molecular biology and genetic variability

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Genetic Heterogeneity of Hepatitis C Virus: Quasispecies and Genotypes

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Prevention of hepatitis C virus infection in chimpanzees by hyperimmune serum against the hypervariable region 1 of the envelope 2 protein

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Induction of specific immune responses by polycation-based vaccines

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Poly-L-arginine synergizes with oligodeoxynucleotides containing CpG-motifs (CpG-ODN) for enhanced and prolonged immune responses and prevents the CpG-ODN-induced systemic release of pro-inflammatory cytokines

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7 January 2021

Rapid effector function in CD8+ memory T cells

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Protamine-reactive natural IgM antibodies in human sera. Characterization of the epitope demonstrates specificity of antigenic recognition; occurrence indicates obscurity of origin and function

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7 January 2021

DNA vaccine strategies for hepatitis C.

1 reference

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7 January 2021

Perspectives: towards a peptide-based vaccine against hepatitis C virus.

1 reference

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7 January 2021

The challenge of developing a vaccine against hepatitis C virus

1 reference

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A candidate vaccine based on the hepatitis C E1 protein: tolerability and immunogenicity in healthy volunteers.

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A pilot study of therapeutic vaccination with envelope protein E1 in 35 patients with chronic hepatitis C.

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1 reference

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7 January 2021

Identifiers

10.1016/J.VACCINE.2006.03.009

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16581161%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

PubMed publication ID

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16581161%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

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