(Q45711023)

English

Lack of DNA binding in the rat nasal mucosa and other tissues of the nasal toxicants roflumilast, a phosphodiesterase 4 inhibitor, and a metabolite, 4-amino-3,5-dichloropyridine, in contrast to the nasal carcinogen 2,6-dimethylaniline

scientific article published in February 2002

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

15 December 2017

Lack of DNA binding in the rat nasal mucosa and other tissues of the nasal toxicants roflumilast, a phosphodiesterase 4 inhibitor, and a metabolite, 4-amino-3,5-dichloropyridine, in contrast to the nasal carcinogen 2,6-dimethylaniline (English)

1 reference

Europe PubMed Central

PubMed publication ID

15 December 2017

author name string

Alan M Jeffrey

1

1 reference

Europe PubMed Central

PubMed publication ID

15 December 2017

Feng-Qi Luo

2

1 reference

Europe PubMed Central

PubMed publication ID

15 December 2017

Shantilal Amin

3

1 reference

Europe PubMed Central

PubMed publication ID

15 December 2017

Jacek Krzeminski

4

1 reference

Europe PubMed Central

PubMed publication ID

15 December 2017

Karl Zech

5

1 reference

Europe PubMed Central

PubMed publication ID

15 December 2017

Gary M Williams

6

1 reference

Europe PubMed Central

PubMed publication ID

15 December 2017

publication date

1 February 2002

1 reference

Europe PubMed Central

PubMed publication ID

15 December 2017

Drug and Chemical Toxicology

1 reference

Europe PubMed Central

PubMed publication ID

15 December 2017

25

1 reference

Europe PubMed Central

PubMed publication ID

15 December 2017

1

1 reference

Europe PubMed Central

PubMed publication ID

15 December 2017

93-107

1 reference

Europe PubMed Central

PubMed publication ID

15 December 2017

Toxicologic and carcinogenic effects of the type IV phosphodiesterase inhibitor RP 73401 on the nasal olfactory tissue in rats

1 reference

https://api.crossref.org/works/10.1081%2FDCT-100108475

21 January 2018

An update of the National Toxicology Program database on nasal carcinogens

1 reference

https://api.crossref.org/works/10.1081%2FDCT-100108475

21 January 2018

32P-labeling test for DNA damage

1 reference

https://api.crossref.org/works/10.1081%2FDCT-100108475

21 January 2018

Determination of 4,4'-methylene-bis(2-chloroaniline)-DNA adduct formation in rat liver and human uroepithelial cells by the 32p postlabeling assay

1 reference

https://api.crossref.org/works/10.1081%2FDCT-100108475

21 January 2018

Review of the genotoxicity and carcinogenicity of 4,4'-methylene-dianiline and 4,4'-methylene-bis-2-chloroaniline

1 reference

https://api.crossref.org/works/10.1081%2FDCT-100108475

21 January 2018

2-Acetylaminofluorene mechanistic data and risk assessment: DNA reactivity, enhanced cell proliferation and tumor initiation

1 reference

https://api.crossref.org/works/10.1081%2FDCT-100108475

21 January 2018

Synthesis, purification and mutagenicity of 2-hydroxyamino-3-methylimidazolo[4,5-f]quinoline.

1 reference

https://api.crossref.org/works/10.1081%2FDCT-100108475

21 January 2018

Synthesis, characterization, and conformational analysis of DNA adducts from methylated anilines present in tobacco smoke.

1 reference

https://api.crossref.org/works/10.1081%2FDCT-100108475

21 January 2018

Revised methods for the Salmonella mutagenicity test

1 reference

https://api.crossref.org/works/10.1081%2FDCT-100108475

21 January 2018

Nuclease P1-mediated enhancement of sensitivity of 32P-postlabeling test for structurally diverse DNA adducts.

1 reference

https://api.crossref.org/works/10.1081%2FDCT-100108475

21 January 2018

Synthesis, characterization, and comparative 32P-postlabeling efficiencies of 2,6-dimethylaniline-DNA adducts.

1 reference

https://api.crossref.org/works/10.1081%2FDCT-100108475

21 January 2018

Toxicological significance of DNA adducts: summary of discussions with an expert panel

1 reference

https://api.crossref.org/works/10.1081%2FDCT-100108475

21 January 2018

Correlation of nucleic acid binding by metabolites of trans-4-aminostilbene derivatives with tissue specific acute toxicity and carcinogenicity in rats

1 reference

https://api.crossref.org/works/10.1081%2FDCT-100108475

21 January 2018

In vivo covalent binding of organic chemicals to DNA as a quantitative indicator in the process of chemical carcinogenesis

1 reference

https://api.crossref.org/works/10.1081%2FDCT-100108475

21 January 2018

Acetochlor-induced rat nasal tumors: further studies on the mode of action and relevance to humans

1 reference

https://api.crossref.org/works/10.1081%2FDCT-100108475

21 January 2018

Covalent binding of [14C]-2,6-dimethylaniline to DNA of rat liver and ethmoid turbinate

1 reference

https://api.crossref.org/works/10.1081%2FDCT-100108475

21 January 2018

Lack of alachlor induced DNA damage as assayed in rodent liver by the alkaline elution test

1 reference

https://api.crossref.org/works/10.1081%2FDCT-100108475

21 January 2018

Methods of DNA adduct determination and their application to testing compounds for genotoxicity

1 reference

https://api.crossref.org/works/10.1081%2FDCT-100108475

21 January 2018

32P-postlabeling of a DNA adduct derived from 4,4'-methylenedianiline, in the olfactory epithelium of rats exposed by inhalation to 4,4'-methylenediphenyl diisocyanate

1 reference

https://api.crossref.org/works/10.1081%2FDCT-100108475

21 January 2018

32P-adduct assay: short- and long-term persistence of 2-acetylaminofluorene-DNA adducts and other applications of the assay

1 reference

https://api.crossref.org/works/10.1081%2FDCT-100108475

21 January 2018

Arylamine–DNA adduct conformation in relation to mutagenesis

1 reference

https://api.crossref.org/works/10.1081%2FDCT-100108475

21 January 2018

Identifiers

10.1081/DCT-100108475

1 reference

Europe PubMed Central

PubMed publication ID

15 December 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

15 December 2017

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