(Q45713873)

15 December 2017

title

The effect of amino-acid substitutions I112P, D147E and K152N in CYP11B2 on the catalytic activities of the enzyme (English)

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15 December 2017

3

Rita Bernhardt

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15 December 2017

Stephanie Bechtel

1

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15 December 2017

Natalya Belkina

series ordinal

2

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15 December 2017

language of work or name

English

0 references

publication date

1 February 2002

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15 December 2017

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15 December 2017

volume

269

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15 December 2017

issue

4

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15 December 2017

page(s)

1118-1127

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Frog cytochrome P-450 (11 beta,aldo), a single enzyme involved in the final steps of glucocorticoid and mineralocorticoid biosynthesis

15 December 2017

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1 reference

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Molecular cloning and nucleotide sequence of DNA of mitochondrial cytochrome P-450(11 beta) of bovine adrenal cortex

21 January 2018

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Cloning and expression of a cDNA for human cytochrome P-450aldo as related to primary aldosteronism

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Different isozymes of mouse 11 beta-hydroxylase produce mineralocorticoids and glucocorticoids

21 January 2018

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Molecular cloning and sequence analysis of cDNA encoding rat adrenal cytochrome P-450(11)beta

21 January 2018

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Cytochrome P450 in adrenocortical mitochondria

21 January 2018

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Glucocorticoid-suppressible hyperaldosteronism results from hybrid genes created by unequal crossovers between CYP11B1 and CYP11B2

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Cloning and sequence analysis of adrenodoxin reductase cDNA from bovine adrenal cortex

21 January 2018

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Adrenodoxin: structure, stability, and electron transfer properties

21 January 2018

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A chimaeric llβ-hydroxylase/aldosterone synthase gene causes glucocorticoid-remediable aldosteronism and human hypertension

21 January 2018

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Molecular variants in the P450c11AS gene as determinants of aldosterone synthase activity in the Dahl rat model of hypertension.

21 January 2018

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Cloning of cDNA and genomic DNA for human cytochrome P-45011 beta

21 January 2018

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Simultaneous transfection of COS-1 cells with mitochondrial and microsomal steroid hydroxylases: incorporation of a steroidogenic pathway into nonsteroidogenic cells

21 January 2018

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Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

21 January 2018

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CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

21 January 2018

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Prediction of protein secondary structure at better than 70% accuracy

21 January 2018

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21 January 2018

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21 January 2018

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Recognition of errors in three-dimensional structures of proteins

21 January 2018

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Conferring aldosterone synthesis to human CYP11B1 by replacing key amino acid residues with CYP11B2-specific ones

21 January 2018

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Interaction of CYP11B1 (cytochrome P-45011 beta) with CYP11A1 (cytochrome P-450scc) in COS-1 cells

21 January 2018

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Disorders of the aldosterone synthase and steroid 11beta-hydroxylase deficiencies

21 January 2018

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A mutation in CYP11B1 (Arg-448----His) associated with steroid 11 beta-hydroxylase deficiency in Jews of Moroccan origin

21 January 2018

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Structure and function of cytochromes P450: a comparative analysis of three crystal structures

21 January 2018

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21 January 2018

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Complex formation in vesicle-reconstituted mitochondrial cytochrome P450 systems (CYP11A1 and CYP11B1) as evidenced by rotational diffusion experiments using EPR and ST-EPR.

21 January 2018

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Nonsubstrate recognition site residues are involved in testosterone hydroxylation by cytochrome P450 CYP 2C11.

21 January 2018

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Cytochrome P-45011 beta and P-450scc in adrenal cortex: zonal distribution and intramitochondrial localization by the horseradish peroxidase-labeled antibody method

21 January 2018

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Engineering a mineralocorticoid- to a glucocorticoid-synthesizing cytochrome P450

21 January 2018

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The amino acid substitutions Ser288Gly and Val320Ala convert the cortisol producing enzyme, CYP11B1, into an aldosterone producing enzyme

21 January 2018

1 reference

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Changed ratios of glucocorticoids/mineralocorticoids caused by point mutations in the putative I-helix regions of CYP11B1 and CYP11B2

21 January 2018

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Structural alignments of P450s and extrapolations to the unknown

21 January 2018

1 reference

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Arginines 97 and 108 in CYP2C9 are important determinants of the catalytic function

21 January 2018

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A close family resemblance: the importance of structure in understanding cytochromes P450

21 January 2018

1 reference

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Modelling of three-dimensional structures of cytochromes P450 11B1 and 11B2

21 January 2018

1 reference

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Modulation of aldosterone biosynthesis by adrenodoxin mutants with different electron transport efficiencies

21 January 2018

1 reference

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Structure/function relationship of CYP11B1 associated with Dahl's salt-resistant rats--expression of rat CYP11B1 and CYP11B2 in Escherichia coli

21 January 2018

1 reference

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Amino acid residues in I- and K-helices of rat CYP11B1 and CYP11B2 are important in expression of 18-hydroxylation activity

21 January 2018

1 reference

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Essential role of the Arg112 residue of cytochrome P450cam for electron transfer from reduced putidaredoxin

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2002.02729.X

10.1046/J.1432-1033.2002.02729.X

21 January 2018

Identifiers

DOI

1 reference

15 December 2017

1 reference