(Q45733826)

15 December 2017

title

Cytosolic p53 inhibits Parkin-mediated mitophagy and promotes mitochondrial dysfunction in the mouse heart (English)

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15 December 2017

Atsushi Hoshino

1

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15 December 2017

Yuichiro Mita

2

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15 December 2017

Yoshifumi Okawa

3

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15 December 2017

Makoto Ariyoshi

4

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15 December 2017

Eri Iwai-Kanai

5

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15 December 2017

Tomomi Ueyama

6

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15 December 2017

Koji Ikeda

7

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15 December 2017

Takehiro Ogata

8

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15 December 2017

Satoaki Matoba

9

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15 December 2017

language of work or name

English

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publication date

1 January 2013

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15 December 2017

published in

Nature Communications

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15 December 2017

volume

4

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15 December 2017

page(s)

2308

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https://scigraph.springernature.com/pub.10.1038/ncomms3308

15 December 2017

exact match

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Mitochondrial oxidative stress mediates angiotensin II-induced cardiac hypertrophy and Galphaq overexpression-induced heart failure

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Regulation of mitochondrial processes: a target for heart failure

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Functions and dysfunctions of mitochondrial dynamics

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Fission and selective fusion govern mitochondrial segregation and elimination by autophagy

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7 January 2021

Parkin is recruited selectively to impaired mitochondria and promotes their autophagy

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7 January 2021

Mechanisms of mitophagy

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https://api.crossref.org/works/10.1038%2FNCOMMS3308

7 January 2021

PINK1 autophosphorylation upon membrane potential dissipation is essential for Parkin recruitment to damaged mitochondria

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7 January 2021

PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1

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7 January 2021

Proteasome and p97 mediate mitophagy and degradation of mitofusins induced by Parkin

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7 January 2021

Contribution of impaired mitochondrial autophagy to cardiac aging: mechanisms and therapeutic opportunities

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Extension of murine life span by overexpression of catalase targeted to mitochondria

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7 January 2021

Premature ageing in mice expressing defective mitochondrial DNA polymerase

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7 January 2021

DNA deletions and clonal mutations drive premature aging in mitochondrial mutator mice

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7 January 2021

Identification of the molecular basis of doxorubicin-induced cardiotoxicity

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7 January 2021

Induction of premature senescence in cardiomyocytes by doxorubicin as a novel mechanism of myocardial damage

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7 January 2021

Role of p53 and p21waf1/cip1 in senescence-like terminal proliferation arrest induced in human tumor cells by chemotherapeutic drugs

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7 January 2021

Doxorubicin induces senescence or apoptosis in rat neonatal cardiomyocytes by regulating the expression levels of the telomere binding factors 1 and 2.

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7 January 2021

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7 January 2021

SIRT5 Deacetylates carbamoyl phosphate synthetase 1 and regulates the urea cycle

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7 January 2021

Identification of a novel Zn2+-binding domain in the autosomal recessive juvenile Parkinson-related E3 ligase parkin.

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7 January 2021

p53 regulates mitochondrial respiration

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7 January 2021

Mitochondria in heart failure: the emerging role of mitochondrial dynamics

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7 January 2021

Mechanisms of mitochondria and autophagy crosstalk

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7 January 2021

PTEN-inducible kinase 1 (PINK1)/Park6 is indispensable for normal heart function

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7 January 2021

Mitochondria: dynamic organelles in disease, aging, and development

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7 January 2021

p53 in health and disease

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7 January 2021

A crucial role for adipose tissue p53 in the regulation of insulin resistance

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7 January 2021

Telomere dysfunction induces metabolic and mitochondrial compromise.

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7 January 2021

Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis

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7 January 2021

Regulation of autophagy by cytoplasmic p53

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7 January 2021

Transcription-independent pro-apoptotic functions of p53.

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7 January 2021

p53 improves aerobic exercise capacity and augments skeletal muscle mitochondrial DNA content

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7 January 2021

Mutation of RRM2B, encoding p53-controlled ribonucleotide reductase (p53R2), causes severe mitochondrial DNA depletion

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7 January 2021

The antioxidant function of the p53 tumor suppressor

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https://api.crossref.org/works/10.1038%2FNCOMMS3308

7 January 2021

Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism

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https://api.crossref.org/works/10.1038%2FNCOMMS3308

7 January 2021

Preconditioning involves selective mitophagy mediated by Parkin and p62/SQSTM1.

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https://api.crossref.org/works/10.1038%2FNCOMMS3308

7 January 2021

PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS3308

7 January 2021

Parkin ubiquitinates and promotes the degradation of RanBP2

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS3308

7 January 2021

Functional modulation of parkin through physical interaction with SUMO-1.

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS3308

7 January 2021

BAG5 inhibits parkin and enhances dopaminergic neuron degeneration

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS3308

7 January 2021

Parkin, a p53 target gene, mediates the role of p53 in glucose metabolism and the Warburg effect

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS3308

7 January 2021

Transcriptional repression of p53 by parkin and impairment by mutations associated with autosomal recessive juvenile Parkinson's disease.

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7 January 2021

PARIS (ZNF746) repression of PGC-1α contributes to neurodegeneration in Parkinson's disease

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https://api.crossref.org/works/10.1038%2FNCOMMS3308

7 January 2021

Parkin-deficient mice exhibit nigrostriatal deficits but not loss of dopaminergic neurons

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https://api.crossref.org/works/10.1038%2FNCOMMS3308

7 January 2021

HL-1 cells: a cardiac muscle cell line that contracts and retains phenotypic characteristics of the adult cardiomyocyte

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https://api.crossref.org/works/10.1038%2FNCOMMS3308

7 January 2021

Requirement for p53 and p21 to sustain G2 arrest after DNA damage

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https://api.crossref.org/works/10.1038%2FNCOMMS3308

7 January 2021

Mitochondrially targeted p53 has tumor suppressor activities in vivo

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https://api.crossref.org/works/10.1038%2FNCOMMS3308

7 January 2021

Identifiers

DOI

10.1038/NCOMMS3308

1 reference

Dimensions Publication ID

15 December 2017

0 references

1012976258

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1 reference