(Q45756120)

English

Characterization of intrastriatal recombinant adeno-associated virus-mediated gene transfer of human tyrosine hydroxylase and human GTP-cyclohydrolase I in a rat model of Parkinson's disease.

scientific article published in June 1998

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scholarly article

1 reference

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11 November 2019

Characterization of intrastriatal recombinant adeno-associated virus-mediated gene transfer of human tyrosine hydroxylase and human GTP-cyclohydrolase I in a rat model of Parkinson's disease (English)

1 reference

Europe PubMed Central

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11 November 2019

Parkinson's disease

1 reference

based on heuristic

inferred from title

author name string

R J Mandel

1

1 reference

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11 November 2019

K G Rendahl

2

1 reference

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11 November 2019

S K Spratt

3

1 reference

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11 November 2019

R O Snyder

4

1 reference

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11 November 2019

L K Cohen

5

1 reference

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11 November 2019

S E Leff

6

1 reference

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11 November 2019

language of work or name

0 references

publication date

1 June 1998

1 reference

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11 November 2019

number of pages

14

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inferred from page(s)

Journal of Neuroscience

1 reference

Europe PubMed Central

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11 November 2019

18

1 reference

Europe PubMed Central

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11 November 2019

4271-4284

1 reference

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11 November 2019

11

1 reference

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11 November 2019

Diminished decarboxylation of L-DOPA in rat striatum after intrastriatal injections of kainic acid

1 reference

https://pubmed.ncbi.nlm.nih.gov/9592104

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NeuN, a neuronal specific nuclear protein in vertebrates

1 reference

https://pubmed.ncbi.nlm.nih.gov/9592104

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Direct intracerebral gene transfer of an adenoviral vector expressing tyrosine hydroxylase in a rat model of Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/9592104

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Behavioral effects and gene delivery in a rat model of Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/9592104

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential and persistent expression patterns of CNS gene transfer by an adeno-associated virus (AAV) vector

1 reference

https://pubmed.ncbi.nlm.nih.gov/9592104

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rationale for continuous dopaminomimetic therapy of Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/9592104

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Suppression of dyskinesias in advanced Parkinson's disease. I. Continuous intravenous levodopa shifts dose response for production of dyskinesias but not for relief of parkinsonism in patients with advanced Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/9592104

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Decarboxylation of exogenous L-DOPA in rat striatum after lesions of the dopaminergic nigrostriatal neurons: the role of striatal capillaries

1 reference

https://pubmed.ncbi.nlm.nih.gov/9592104

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuropathological evidence of graft survival and striatal reinnervation after the transplantation of fetal mesencephalic tissue in a patient with Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/9592104

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Estimation of nuclear population from microtome sections

1 reference

https://pubmed.ncbi.nlm.nih.gov/9592104

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cellular immunity to viral antigens limits E1-deleted adenoviruses for gene therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/9592104

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biopterin in human brain and urine from controls and parkinsonian patients: Application of a new radioimmunoassay

1 reference

https://pubmed.ncbi.nlm.nih.gov/9592104

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dopaminergic transplants normalize amphetamine- and apomorphine-induced Fos expression in the 6-hydroxydopamine-lesioned striatum.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9592104

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Continuous and intermittent levodopa differentially affect rotation induced by D-1 and D-2 dopamine agonists

1 reference

https://pubmed.ncbi.nlm.nih.gov/9592104

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Motor response complications and the function of striatal efferent systems

1 reference

https://pubmed.ncbi.nlm.nih.gov/9592104

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Long-term gene expression and phenotypic correction using adeno-associated virus vectors in the mammalian brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/9592104

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

1 Production of antibodies by inoculation into lymph nodes

1 reference

https://pubmed.ncbi.nlm.nih.gov/9592104

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tetrahydrobiopterin in Striatum: Localization in Dopamine Nerve Terminals and Role in Catecholamine Synthesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/9592104

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical application of cell transplantation and neurotrophic factors in CNS disorders

1 reference

https://pubmed.ncbi.nlm.nih.gov/9592104

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vivo gene transfer by intravenous administration of stable cationic lipid/DNA complex

1 reference

https://pubmed.ncbi.nlm.nih.gov/9592104

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Long-term behavioral recovery in parkinsonian rats by an HSV vector expressing tyrosine hydroxylase

1 reference

https://pubmed.ncbi.nlm.nih.gov/9592104

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantitative recording of rotational behavior in rats after 6-hydroxy-dopamine lesions of the nigrostriatal dopamine system.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9592104

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Some new, simple and efficient stereological methods and their use in pathological research and diagnosis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9592104

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Second-strand synthesis is a rate-limiting step for efficient transduction by recombinant adeno-associated virus vectors

1 reference

https://pubmed.ncbi.nlm.nih.gov/9592104

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aromatic L-amino acid decarboxylase in rat corpus striatum: implications for action of L-dopa in parkinsonism

1 reference

https://pubmed.ncbi.nlm.nih.gov/9592104

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rotation and striatal c-fos expression after repeated, daily treatment with selective dopamine receptor agonists and levodopa

1 reference

https://pubmed.ncbi.nlm.nih.gov/9592104

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Helper-free stocks of recombinant adeno-associated viruses: normal integration does not require viral gene expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/9592104

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aromatic L-amino acid decarboxylase immunoreactive cells in the rat striatum: a possible site for the conversion of exogenous L-DOPA to dopamine

1 reference

https://pubmed.ncbi.nlm.nih.gov/9592104

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Trans-activation of human immunodeficiency virus occurs via a bimodal mechanism

1 reference

https://pubmed.ncbi.nlm.nih.gov/9592104

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector

1 reference

https://pubmed.ncbi.nlm.nih.gov/9592104

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amphetamine induces excess release of striatal acetylcholine in vivo that is independent of nigrostriatal dopamine.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9592104

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Midbrain injection of recombinant adeno-associated virus encoding rat glial cell line-derived neurotrophic factor protects nigral neurons in a progressive 6-hydroxydopamine-induced degeneration model of Parkinson's disease in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/9592104

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of pulsatile versus continuous dopamine receptor stimulation for functional recovery in Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/9592104

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tetrahydrobiopterin uptake into rat brain synaptosomes, cultured PC12 cells, and rat striatum

1 reference

https://pubmed.ncbi.nlm.nih.gov/9592104

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Survival and function of dissociated rat dopamine neurones grafted at different developmental stages or after being cultured in vitro.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9592104

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chronic continuous and intermittent L-3,4-dihydroxyphenylalanine treatments differentially affect basal ganglia function in 6-hydroxydopamine lesioned rats--an autoradiographic study using [3H]flunitrazepam

1 reference

https://pubmed.ncbi.nlm.nih.gov/9592104

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Levodopa replacement therapy alters enzyme activities in striatum and neuropeptide content in striatal output regions of 6-hydroxydopamine lesioned rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/9592104

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Grafting genetically modified cells to the brain: possibilities for the future

1 reference

https://pubmed.ncbi.nlm.nih.gov/9592104

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Catecholamine-related enzymes and the biopterin cofactor in Parkinson's disease and related extrapyramidal diseases

1 reference

https://pubmed.ncbi.nlm.nih.gov/9592104

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intracerebral grafting of neuronal cell suspensions. III. Activity of intrastriatal nigral suspension implants as assessed by measurements of dopamine synthesis and metabolism.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9592104

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The regional distribution of hydroxylase cofactor in rat brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/9592104

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Highly efficient and sustained gene transfer in adult neurons with a lentivirus vector.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9592104

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The decarboxylation of DOPA in the parkinsonian brain: in vivo studies on an animal model

1 reference

https://pubmed.ncbi.nlm.nih.gov/9592104

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tetrahydrobiopterin-dependent functional recovery in 6-hydroxydopamine-treated rats by intracerebral grafting of fibroblasts transfected with tyrosine hydroxylase cDNA

1 reference

https://pubmed.ncbi.nlm.nih.gov/9592104

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adeno-associated virus vectors for gene therapy of neurodegenerative disorders

1 reference

https://pubmed.ncbi.nlm.nih.gov/9592104

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nonaminergic striatal neurons convert exogenous l-dopa to dopamine in parkinsonism

1 reference

https://pubmed.ncbi.nlm.nih.gov/9592104

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Unilateral transplantation of human fetal mesencephalic tissue into the caudate nucleus of patients with Parkinson's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9592104

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ibotenic acid lesions of the striatum reduce drug-induced rotation in the 6-hydroxydopamine-lesioned rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/9592104

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Persistent and therapeutic concentrations of human factor IX in mice after hepatic gene transfer of recombinant AAV vectors

1 reference

https://pubmed.ncbi.nlm.nih.gov/9592104

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Endogenous release of neuronal serotonin and 5-hydroxyindoleacetic acid in the caudate-putamen of the rat as revealed by intracerebral dialysis coupled to high-performance liquid chromatography with fluorimetric detection.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9592104

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Use of Adeno-Associated Virus as a General Transduction Vector for Mammalian Cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/9592104

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vivo L-DOPA production by genetically modified primary rat fibroblast or 9L gliosarcoma cell grafts via coexpression of GTPcyclohydrolase I with tyrosine hydroxylase

1 reference

https://pubmed.ncbi.nlm.nih.gov/9592104

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Survival of implanted fetal dopamine cells and neurologic improvement 12 to 46 months after transplantation for Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/9592104

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hydroxylase Cofactor Activity in Cerebrospinal Fluid of Normal Subjects and Patients with Parkinson's Disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/9592104

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The site of dopamine formation in rat striatum after L-dopa administration

1 reference

https://pubmed.ncbi.nlm.nih.gov/9592104

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tyrosine hydroxylase cofactor (tetrahydrobiopterin) in parkinsonism

1 reference

https://pubmed.ncbi.nlm.nih.gov/9592104

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A defective herpes simplex virus vector system for gene delivery into the brain: comparison with alternative gene delivery systems and usefulness for gene therapy.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9592104

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Normalization of spiroperidol binding in the denervated rat striatum by homologous grafts of substantia nigra.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9592104

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The unlabeled antibody enzyme method of immunohistochemistry: preparation and properties of soluble antigen-antibody complex (horseradish peroxidase-antihorseradish peroxidase) and its use in identification of spirochetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/9592104

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evaluation of promoter strength for hepatic gene expression in vivo following adenovirus-mediated gene transfer

1 reference

https://pubmed.ncbi.nlm.nih.gov/9592104

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Double transduction with GTP cyclohydrolase I and tyrosine hydroxylase is necessary for spontaneous synthesis of L-DOPA by primary fibroblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/9592104

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human GTP cyclohydrolase I: only one out of three cDNA isoforms gives rise to the active enzyme

1 reference

https://pubmed.ncbi.nlm.nih.gov/9592104

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neural transplantation

1 reference

https://pubmed.ncbi.nlm.nih.gov/9592104

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Grafting fibroblasts genetically modified to produce L-dopa in a rat model of Parkinson disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/9592104

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bilateral fetal mesencephalic grafting in two patients with parkinsonism induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)

1 reference

https://pubmed.ncbi.nlm.nih.gov/9592104

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neural transplantation — an experimental tool with clinical possibilities

1 reference

https://pubmed.ncbi.nlm.nih.gov/9592104

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The new stereological tools: disector, fractionator, nucleator and point sampled intercepts and their use in pathological research and diagnosis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9592104

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Use of a new fluorogenic phosphatase substrate in immunohistochemical applications

1 reference

https://pubmed.ncbi.nlm.nih.gov/9592104

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Production of reagent antibodies

1 reference

https://pubmed.ncbi.nlm.nih.gov/9592104

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.18-11-04271.1998

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9592104%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9592104%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9592104%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

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