(Q45771316)

15 December 2017

title

p27(Kip1) inhibits systemic autoimmunity through the control of Treg cell activity and differentiation (English)

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15 December 2017

author name string

Marcos Iglesias

1

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15 December 2017

Jorge Postigo

2

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15 December 2017

Inés Santiuste

3

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15 December 2017

Jovanna González

4

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15 December 2017

Luis Buelta

5

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15 December 2017

Esther Tamayo

6

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15 December 2017

Jesús Merino

7

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15 December 2017

Ramón Merino

8

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15 December 2017

publication date

1 February 2013

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15 December 2017

published in

Arthritis & Rheumatology

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15 December 2017

volume

65

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15 December 2017

issue

2

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15 December 2017

page(s)

343-354

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15 December 2017

JM2, encoding a fork head-related protein, is mutated in X-linked autoimmunity-allergic disregulation syndrome

cites work

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The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3

21 January 2018

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Foxp3 programs the development and function of CD4+CD25+ regulatory T cells

21 January 2018

1 reference

Control of regulatory T cell development by the transcription factor Foxp3

21 January 2018

1 reference

An essential role for Scurfin in CD4+CD25+ T regulatory cells

21 January 2018

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Regulatory T cells and treatment of cancer

21 January 2018

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Role of endogenous and induced regulatory T cells during infections

21 January 2018

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Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3

21 January 2018

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TGF-beta: a master of all T cell trades

21 January 2018

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Transforming growth factor-beta signaling curbs thymic negative selection promoting regulatory T cell development

21 January 2018

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Cross talk between cell death and cell cycle progression: BCL-2 regulates NFAT-mediated activation.

21 January 2018

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Bcl-2 retards cell cycle entry through p27(Kip1), pRB relative p130, and altered E2F regulation

21 January 2018

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A pathway regulated by cell cycle inhibitor p27Kip1 and checkpoint inhibitor Smad3 is involved in the induction of T cell tolerance.

21 January 2018

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bcl-2 inhibits multiple forms of apoptosis but not negative selection in thymocytes

21 January 2018

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B-cell overexpression of Bcl-2 cooperates with p21 deficiency for the induction of autoimmunity and lymphomas

21 January 2018

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Inhibition of B cell death causes the development of an IgA nephropathy in (New Zealand white x C57BL/6)F(1)-bcl-2 transgenic mice.

21 January 2018

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BCL2A1: the underdog in the BCL2 family

21 January 2018

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Cyclin-dependent kinases regulate the antiproliferative function of Smads

21 January 2018

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FoxP3 and Bcl-xL cooperatively promote regulatory T cell persistence and prevention of arthritis development

21 January 2018

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Expression of Helios, an Ikaros transcription factor family member, differentiates thymic-derived from peripherally induced Foxp3+ T regulatory cells

21 January 2018

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A syndrome of multiorgan hyperplasia with features of gigantism, tumorigenesis, and female sterility in p27(Kip1)-deficient mice

21 January 2018

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Mice lacking p27(Kip1) display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors

21 January 2018

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Amelioration of lupus-like autoimmune disease in NZB/WF1 mice after treatment with a blocking monoclonal antibody specific for complement component C5.

21 January 2018

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Uncoupling of immune complex formation and kidney damage in autoimmune glomerulonephritis.

21 January 2018

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IgM and IgA anti-erythrocyte autoantibodies induce anemia in a mouse model through multivalency-dependent hemagglutination but not through complement activation

21 January 2018

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Critical roles of Bim in T cell activation and T cell-mediated autoimmune inflammation in mice

21 January 2018

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The AKT-mTOR axis regulates de novo differentiation of CD4+Foxp3+ cells

21 January 2018

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p27Kip1 modulates cell migration through the regulation of RhoA activation.

21 January 2018

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Phosphatidylinositol 3-kinase function is required for transforming growth factor beta-mediated epithelial to mesenchymal transition and cell migration.

21 January 2018

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Expression of Helios in Peripherally Induced Foxp3+ Regulatory T Cells

21 January 2018

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Bcl-xL is required for the development of functional regulatory CD4 cells in lupus-afflicted mice following treatment with a tolerogenic peptide

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/ART.37778

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15 December 2017

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15 December 2017