(Q45781827)

16 December 2017

title

Activin receptor-like kinase 5 inhibition reverses impairment of endothelial cell viability by endogenous islet mesenchymal stromal cells (English)

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16 December 2017

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16 December 2017

Peter M Jones

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Peter M Jones

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author name string

Claire E Clarkin

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16 December 2017

Paramjeet Dhadda

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16 December 2017

Pedro Chagastelles

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16 December 2017

Nance Nardi

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16 December 2017

Caroline P Wheeler-Jones

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16 December 2017

publication date

1 March 2013

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16 December 2017

published in

Stem Cells

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16 December 2017

volume

31

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16 December 2017

issue

3

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16 December 2017

page(s)

547-559

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16 December 2017

'Giving and taking': endothelial and beta-cells in the islets of Langerhans

cites work

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Endothelial cell signalling supports pancreatic beta cell function in the rat.

21 January 2018

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Thrombospondin-1: an islet endothelial cell signal of importance for β-cell function.

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Intraislet endothelial cells contribute to revascularization of transplanted pancreatic islets

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Better vascular engraftment and function in pancreatic islets transplanted without prior culture

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Increased islet cell proliferation, decreased apoptosis, and greater vascularization leading to beta-cell hyperplasia in mutant mice lacking insulin

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VEGF-A has a critical, nonredundant role in angiogenic switching and pancreatic beta cell carcinogenesis

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Role of VEGF-A in vascularization of pancreatic islets

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TGF-beta signaling: a tale of two responses

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Extracellular control of TGFbeta signalling in vascular development and disease

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Endoglin promotes endothelial cell proliferation and TGF-beta/ALK1 signal transduction

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Activin receptor-like kinase 1 modulates transforming growth factor-beta 1 signaling in the regulation of angiogenesis

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Endoglin, a TGF-beta binding protein of endothelial cells, is the gene for hereditary haemorrhagic telangiectasia type 1

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Controlling the angiogenic switch: a balance between two distinct TGF-b receptor signaling pathways

21 January 2018

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Somatostatin secreted by islet delta-cells fulfills multiple roles as a paracrine regulator of islet function

21 January 2018

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The development of new density gradient media for purifying human islets and islet-quality assessments

21 January 2018

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Vascular endothelial growth factor receptor-2 couples cyclo-oxygenase-2 with pro-angiogenic actions of leptin on human endothelial cells

21 January 2018

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Mesenchymal stem cells reside in virtually all post-natal organs and tissues

21 January 2018

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Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement

21 January 2018

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Id-1 expression and cell survival

21 January 2018

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Mesenchymal stem cells from adipose and bone marrow promote angiogenesis via distinct cytokine and protease expression mechanisms

21 January 2018

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Serum-deprived human multipotent mesenchymal stromal cells (MSCs) are highly angiogenic

21 January 2018

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SB-431542 is a potent and specific inhibitor of transforming growth factor-beta superfamily type I activin receptor-like kinase (ALK) receptors ALK4, ALK5, and ALK7

21 January 2018

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VEGF and inhibitors of TGFbeta type-I receptor kinase synergistically promote blood-vessel formation by inducing alpha5-integrin expression.

21 January 2018

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Defective paracrine signalling by TGFbeta in yolk sac vasculature of endoglin mutant mice: a paradigm for hereditary haemorrhagic telangiectasia

21 January 2018

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Expression of nephrin by human pancreatic islet endothelial cells

21 January 2018

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Primary and immortalised human pancreatic islet endothelial cells: phenotypic and immunological characterisation.

21 January 2018

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Hyperglycemia induces apoptosis of human pancreatic islet endothelial cells: effects of pravastatin on the Akt survival pathway

21 January 2018

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Expression of CD86 on human islet endothelial cells facilitates T cell adhesion and migration.

21 January 2018

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Human pancreatic islet endothelial cells express coxsackievirus and adenovirus receptor and are activated by coxsackie B virus infection

21 January 2018

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Generation and expansion of multipotent mesenchymal progenitor cells from cultured human pancreatic islets

21 January 2018

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Isolated human islets contain a distinct population of mesenchymal stem cells

21 January 2018

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Endoglin promotes transforming growth factor beta-mediated Smad 1/5/8 signaling and inhibits endothelial cell migration through its association with GIPC.

21 January 2018

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Colorectal carcinoma cell production of transforming growth factor beta decreases expression of endothelial cell vascular endothelial growth factor receptor 2.

21 January 2018

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Vascular progenitors derived from murine bone marrow stromal cells are regulated by fibroblast growth factor and are avidly recruited by vascularizing tumors

21 January 2018

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Mesenchymal stem cells: Stem cell therapy perspectives for type 1 diabetes

21 January 2018

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Mesenchymal stem cells enhance allogeneic islet engraftment in nonhuman primates

21 January 2018

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Mesenchymal stem cell and islet co-transplantation promotes graft revascularization and function.

21 January 2018

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Mesenchymal stem cells prevent the rejection of fully allogenic islet grafts by the immunosuppressive activity of matrix metalloproteinase-2 and -9

21 January 2018

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Inhibition of capillary endothelial cell growth by pericytes and smooth muscle cells

21 January 2018

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An activated form of transforming growth factor beta is produced by cocultures of endothelial cells and pericytes

21 January 2018

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Concentration-dependent inhibition of angiogenesis by mesenchymal stem cells

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/STEM.1305

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16 December 2017

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16 December 2017