(Q45833523)

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Succinate dehydrogenase deficiency is associated with decreased 5-hydroxymethylcytosine production in gastrointestinal stromal tumors: implications for mechanisms of tumorigenesis

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

16 December 2017

http://europepmc.org/abstract/MED/23743927

Succinate dehydrogenase deficiency is associated with decreased 5-hydroxymethylcytosine production in gastrointestinal stromal tumors: implications for mechanisms of tumorigenesis (English)

1 reference

Europe PubMed Central

PubMed publication ID

16 December 2017

http://europepmc.org/abstract/MED/23743927

Jason L. Hornick

2

1 reference

Europe PubMed Central

PubMed publication ID

16 December 2017

http://europepmc.org/abstract/MED/23743927

author name string

Emily F Mason

1

1 reference

Europe PubMed Central

PubMed publication ID

16 December 2017

http://europepmc.org/abstract/MED/23743927

publication date

7 June 2013

1 reference

Europe PubMed Central

PubMed publication ID

16 December 2017

http://europepmc.org/abstract/MED/23743927

Modern Pathology

1 reference

Europe PubMed Central

PubMed publication ID

16 December 2017

http://europepmc.org/abstract/MED/23743927

26

1 reference

Europe PubMed Central

PubMed publication ID

16 December 2017

http://europepmc.org/abstract/MED/23743927

11

1 reference

Europe PubMed Central

PubMed publication ID

16 December 2017

http://europepmc.org/abstract/MED/23743927

1492-1497

1 reference

Europe PubMed Central

PubMed publication ID

16 December 2017

http://europepmc.org/abstract/MED/23743927

Predictors of response to targeted therapies for gastrointestinal stromal tumors

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2013.86

21 January 2018

Gastrointestinal stromal tumour.

1 reference

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Efficacy and safety of imatinib mesylate in advanced gastrointestinal stromal tumors

1 reference

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Efficacy and safety of sunitinib in patients with advanced gastrointestinal stromal tumour after failure of imatinib: a randomised controlled trial

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Gastrointestinal stromal tumors in children and young adults: a clinicopathologic, molecular, and genomic study of 15 cases and review of the literature

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2013.86

21 January 2018

Molecular characterization of pediatric gastrointestinal stromal tumors.

1 reference

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21 January 2018

V600E BRAF mutations are alternative early molecular events in a subset of KIT/PDGFRA wild-type gastrointestinal stromal tumours.

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2013.86

21 January 2018

Novel V600E BRAF mutations in imatinib-naive and imatinib-resistant gastrointestinal stromal tumors

1 reference

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21 January 2018

BRAF mutation status in gastrointestinal stromal tumors.

1 reference

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21 January 2018

Succinate Dehydrogenase Subunit B (SDHB) Is Expressed in Neurofibromatosis 1-Associated Gastrointestinal Stromal Tumors (Gists): Implications for the SDHB Expression Based Classification of Gists

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2013.86

21 January 2018

Succinate dehydrogenase-deficient tumors: diagnostic advances and clinical implications

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2013.86

21 January 2018

Clinical and molecular genetics of patients with the Carney-Stratakis syndrome and germline mutations of the genes coding for the succinate dehydrogenase subunits SDHB, SDHC, and SDHD.

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2013.86

21 January 2018

Defects in succinate dehydrogenase in gastrointestinal stromal tumors lacking KIT and PDGFRA mutations

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2013.86

21 January 2018

SDHA loss of function mutations in a subset of young adult wild-type gastrointestinal stromal tumors

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2013.86

21 January 2018

SDHA loss-of-function mutations in KIT-PDGFRA wild-type gastrointestinal stromal tumors identified by massively parallel sequencing

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2013.86

21 January 2018

Loss of SDHA expression identifies SDHA mutations in succinate dehydrogenase-deficient gastrointestinal stromal tumors.

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2013.86

21 January 2018

Immunohistochemical loss of succinate dehydrogenase subunit A (SDHA) in gastrointestinal stromal tumors (GISTs) signals SDHA germline mutation

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2013.86

21 January 2018

C-KIT mutations were closely associated with the response to Imatinib in Chinese advanced gastrointestinal stromal tumor patients.

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2013.86

21 January 2018

Accumulation of Krebs cycle intermediates and over-expression of HIF1alpha in tumours which result from germline FH and SDH mutations

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2013.86

21 January 2018

Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF-alpha prolyl hydroxylase

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2013.86

21 January 2018

Inhibition of α-KG-dependent histone and DNA demethylases by fumarate and succinate that are accumulated in mutations of FH and SDH tumor suppressors

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2013.86

21 January 2018

Tet family proteins and 5-hydroxymethylcytosine in development and disease

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2013.86

21 January 2018

Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2013.86

21 January 2018

Identification of a CpG island methylator phenotype that defines a distinct subgroup of glioma

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2013.86

21 January 2018

Tumor development is associated with decrease of TET gene expression and 5-methylcytosine hydroxylation

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2013.86

21 January 2018

Loss of 5-hydroxymethylcytosine is an epigenetic hallmark of melanoma

1 reference

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21 January 2018

Somatic mosaic IDH1 and IDH2 mutations are associated with enchondroma and spindle cell hemangioma in Ollier disease and Maffucci syndrome

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2013.86

21 January 2018

The role of mutations in epigenetic regulators in myeloid malignancies

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2013.86

21 January 2018

IDH1 and IDH2 mutations in gliomas

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2013.86

21 January 2018

IDH1 and IDH2 mutations are frequent events in central chondrosarcoma and central and periosteal chondromas but not in other mesenchymal tumours

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2013.86

21 January 2018

IDH mutations: new genetic signatures in cholangiocarcinoma and therapeutic implications.

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2013.86

21 January 2018

Mitochondrial tumour suppressors: a genetic and biochemical update

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2013.86

21 January 2018

Cancer and altered metabolism: potential importance of hypoxia-inducible factor and 2-oxoglutarate-dependent dioxygenases

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2013.86

21 January 2018

Inhibition of succinate dehydrogenase dysregulates histone modification in mammalian cells

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2013.86

21 January 2018

Impaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2013.86

21 January 2018

The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting alpha-ketoglutarate to 2-hydroxyglutarate

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2013.86

21 January 2018

Alterations of metabolic genes and metabolites in cancer

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2013.86

21 January 2018

A distinct pediatric-type gastrointestinal stromal tumor in adults: potential role of succinate dehydrogenase subunit A mutations

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2013.86

21 January 2018

Gastrointestinal stromal tumors

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2013.86

7 January 2021

based on heuristic

inferred from DOI database lookup

Loss of expression of SDHA predicts SDHA mutations in gastrointestinal stromal tumors

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2013.86

7 January 2021

based on heuristic

inferred from DOI database lookup

SDHA mutations in adult and pediatric wild-type gastrointestinal stromal tumors

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2013.86

7 January 2021

based on heuristic

inferred from DOI database lookup

Loss of succinate dehydrogenase subunit B (SDHB) expression is limited to a distinctive subset of gastric wild-type gastrointestinal stromal tumours: a comprehensive genotype-phenotype correlation study

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2013.86

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1038/MODPATHOL.2013.86

1 reference

Europe PubMed Central

PubMed publication ID

16 December 2017

http://europepmc.org/abstract/MED/23743927

Dimensions Publication ID

0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

16 December 2017

http://europepmc.org/abstract/MED/23743927

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