(Q45855548)

English

Reversion of the biochemical defects in murine embryonic Sandhoff neurons using a bicistronic lentiviral vector encoding hexosaminidase alpha and beta

scientific article published on 25 January 2006

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scholarly article

1 reference

Europe PubMed Central

17 December 2017

http://europepmc.org/abstract/MED/16441513

Reversion of the biochemical defects in murine embryonic Sandhoff neurons using a bicistronic lentiviral vector encoding hexosaminidase alpha and beta (English)

1 reference

Europe PubMed Central

17 December 2017

http://europepmc.org/abstract/MED/16441513

Anthony H. Futerman

6

1 reference

Europe PubMed Central

17 December 2017

http://europepmc.org/abstract/MED/16441513

author name string

Audrey Arfi

1

1 reference

Europe PubMed Central

17 December 2017

http://europepmc.org/abstract/MED/16441513

Rivka Zisling

2

1 reference

Europe PubMed Central

17 December 2017

http://europepmc.org/abstract/MED/16441513

Emmanuel Richard

3

1 reference

Europe PubMed Central

17 December 2017

http://europepmc.org/abstract/MED/16441513

Lionel Batista

4

1 reference

Europe PubMed Central

17 December 2017

http://europepmc.org/abstract/MED/16441513

Livia Poenaru

5

1 reference

Europe PubMed Central

17 December 2017

http://europepmc.org/abstract/MED/16441513

Catherine Caillaud

7

1 reference

Europe PubMed Central

17 December 2017

http://europepmc.org/abstract/MED/16441513

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publication date

25 January 2006

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Europe PubMed Central

17 December 2017

http://europepmc.org/abstract/MED/16441513

Journal of Neurochemistry

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Europe PubMed Central

17 December 2017

http://europepmc.org/abstract/MED/16441513

96

1 reference

Europe PubMed Central

17 December 2017

http://europepmc.org/abstract/MED/16441513

6

1 reference

Europe PubMed Central

17 December 2017

http://europepmc.org/abstract/MED/16441513

1572-1579

1 reference

Europe PubMed Central

17 December 2017

http://europepmc.org/abstract/MED/16441513

Bicistronic lentiviral vector corrects beta-hexosaminidase deficiency in transduced and cross-corrected human Sandhoff fibroblasts.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03665.X

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Optimized survival of hippocampal neurons in B27-supplemented Neurobasal, a new serum-free medium combination

1 reference

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High-efficiency transformation of mammalian cells by plasmid DNA

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03665.X

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The cell biology of lysosomal storage disorders

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03665.X

21 January 2018

The pathogenesis of glycosphingolipid storage disorders

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03665.X

21 January 2018

Physiological substrates for human lysosomal beta -hexosaminidase S.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03665.X

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The long-chain sphingoid base of sphingolipids is acylated at the cytosolic surface of the endoplasmic reticulum in rat liver

1 reference

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Central nervous system inflammation is a hallmark of pathogenesis in mouse models of GM1 and GM2 gangliosidosis

1 reference

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Neonatal gene therapy of MPS I mice by intravenous injection of a lentiviral vector

1 reference

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21 January 2018

Elevation of intracellular glucosylceramide levels results in an increase in endoplasmic reticulum density and in functional calcium stores in cultured neurons.

1 reference

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21 January 2018

Biochemical consequences of mutations causing the GM2 gangliosidoses

1 reference

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Development of minimal lentivirus vectors derived from simian immunodeficiency virus (SIVmac251) and their use for gene transfer into human dendritic cells

1 reference

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21 January 2018

Molecular pathophysiology in Tay-Sachs and Sandhoff diseases as revealed by gene expression profiling.

1 reference

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21 January 2018

Death-associated protein (DAP) kinase plays a central role in ceramide-induced apoptosis in cultured hippocampal neurons

1 reference

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21 January 2018

Reduced rates of axonal and dendritic growth in embryonic hippocampal neurones cultured from a mouse model of Sandhoff disease.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03665.X

21 January 2018

Inhibition of calcium uptake via the sarco/endoplasmic reticulum Ca2+-ATPase in a mouse model of Sandhoff disease and prevention by treatment with N-butyldeoxynojirimycin

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03665.X

21 January 2018

Dramatically different phenotypes in mouse models of human Tay-Sachs and Sandhoff diseases

1 reference

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21 January 2018

Mouse models of Tay-Sachs and Sandhoff diseases differ in neurologic phenotype and ganglioside metabolism

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03665.X

21 January 2018

Mice lacking both subunits of lysosomal beta-hexosaminidase display gangliosidosis and mucopolysaccharidosis

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03665.X

21 January 2018

Lysosomal storage results in impaired survival but normal neurite outgrowth in dorsal root ganglion neurones from a mouse model of Sandhoff disease.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03665.X

21 January 2018

A regulatory role for sphingolipids in neuronal growth. Inhibition of sphingolipid synthesis and degradation have opposite effects on axonal branching.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03665.X

21 January 2018

A tool coming of age: thapsigargin as an inhibitor of sarco-endoplasmic reticulum Ca(2+)-ATPases.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03665.X

21 January 2018

Metabolic correction in microglia derived from Sandhoff disease model mice

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03665.X

21 January 2018

Microglial activation precedes acute neurodegeneration in Sandhoff disease and is suppressed by bone marrow transplantation

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03665.X

21 January 2018

Inflammation in neurodegenerative disease--a double-edged sword

1 reference

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21 January 2018

Gene transfer into the central nervous system in vivo using a recombinanat lentivirus vector.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03665.X

21 January 2018

Identifiers

10.1111/J.1471-4159.2006.03665.X

1 reference

Europe PubMed Central

17 December 2017

http://europepmc.org/abstract/MED/16441513

1 reference

Europe PubMed Central

17 December 2017

http://europepmc.org/abstract/MED/16441513

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