(Q45856152)

17 December 2017

review article

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title

Neurotrophin gene therapy in CNS models of trauma and degeneration (English)

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17 December 2017

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1

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17 December 2017

author name string

Grill RJ

series ordinal

2

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17 December 2017

Tuszynski MH

series ordinal

3

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17 December 2017

publication date

1 January 1998

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17 December 2017

Progress in Brain Research

published in

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17 December 2017

volume

117

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17 December 2017

page(s)

473-484

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17 December 2017

Effects of scopolamine and physostigmine on recognition memory in monkeys with ibotenic-acid lesions of the nucleus basalis of Meynert

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Neurotrophin-3 prevents the death of adult central noradrenergic neurons in vivo

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Response of septal cholinergic neurons to axotomy

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Regeneration in the adult mammalian CNS: guided by development

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Perspectives on axonal regeneration in the mammalian CNS.

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The cholinergic hypothesis of geriatric memory dysfunction

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Quantitative histochemistry of brain acetylcholinesterase and learning rate in the aged rat.

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7 January 2021

Intrastriatal injection of an adenoviral vector expressing glial-cell-line-derived neurotrophic factor prevents dopaminergic neuron degeneration and behavioral impairment in a rat model of Parkinson disease.

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7 January 2021

Recovery of function after spinal cord injury: mechanisms underlying transplant-mediated recovery of function differ after spinal cord injury in newborn and adult rats.

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Recovery from spinal cord injury mediated by antibodies to neurite growth inhibitors

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Somatic gene transfer of NGF to the aged brain: behavioral and morphological amelioration

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Spinal cord repair in adult paraplegic rats: partial restoration of hind limb function

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Dopaminergic neurons protected from degeneration by GDNF gene therapy

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7 January 2021

Alzheimer's Disease: A Disorder of Cortical Cholinergic Innervation

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In vitro Evidence for two distinct hippocampal growth factors: basis of neuronal plasticity?

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7 January 2021

Axonal Elongation into Peripheral Nervous System "Bridges" After Central Nervous System Injury in Adult Rats

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7 January 2021

Implants of encapsulated human CNTF-producing fibroblasts prevent behavioral deficits and striatal degeneration in a rodent model of Huntington's disease

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7 January 2021

Protective effect of encapsulated cells producing neurotrophic factor CNTF in a monkey model of Huntington's disease

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7 January 2021

Implants of polymer-encapsulated human NGF-secreting cells in the nonhuman primate: rescue and sprouting of degenerating cholinergic basal forebrain neurons

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7 January 2021

Amelioration of cholinergic neuron atrophy and spatial memory impairment in aged rats by nerve growth factor.

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7 January 2021

Cells engineered to produce acetylcholine: therapeutic potential for Alzheimer's disease

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7 January 2021

In vivo production and release of acetylcholine from primary fibroblasts genetically modified to express choline acetyltransferase.

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7 January 2021

Morphological response of axotomized septal neurons to nerve growth factor

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7 January 2021

Genetically modified cells: applications for intracerebral grafting

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7 January 2021

Grafting genetically modified cells to the brain: possibilities for the future

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7 January 2021

BDNF and NT-3, but not NGF, prevent axotomy-induced death of rat corticospinal neurons in vivo

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7 January 2021

Criteria for assessing recovery of function after spinal cord injury: behavioral methods

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7 January 2021

Transcriptional activation by tetracyclines in mammalian cells

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7 January 2021

Cellular delivery of neurotrophin-3 promotes corticospinal axonal growth and partial functional recovery after spinal cord injury.

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7 January 2021

Robust growth of chronically injured spinal cord axons induced by grafts of genetically modified NGF-secreting cells

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7 January 2021

Nerve growth factor promotes survival of septal cholinergic neurons after fimbrial transections

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7 January 2021

Chronic intraventricular injections of nerve growth factor elevate hippocampal choline acetyltransferase activity in adult rats with partial septo-hippocampal lesions

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7 January 2021

Grafts of fetal central nervous system tissue rescue axotomized Clarke's nucleus neurons in adult and neonatal operates.

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7 January 2021

In vivo release of dopa and dopamine from genetically engineered cells grafted to the denervated rat striatum

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7 January 2021

Stability of numbers but not size of mouse forebrain cholinergic neurons to 53 months

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7 January 2021

Demonstration of the potential for chronically injured neurons to regenerate axons into intraspinal peripheral nerve grafts.

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7 January 2021

Transplantation of fetal spinal cord tissue into the chronically injured adult rat spinal cord

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7 January 2021

Bridging a complete transection lesion of adult rat spinal cord with growth factor-treated nitrocellulose implants

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7 January 2021

Collagen implants and cortico-spinal axonal growth after mid-thoracic spinal cord lesion in the adult rat

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7 January 2021

Regulation of dopamine production by genetically modified primary fibroblasts

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7 January 2021

Somatic gene transfer of nerve growth factor promotes the survival of axotomized septal neurons and the regeneration of their axons in adult rats

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7 January 2021

Mouse nerve growth factor prevents degeneration of axotomized basal forebrain cholinergic neurons in the monkey.

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7 January 2021

The aged monkey basal forebrain: rescue and sprouting of axotomized basal forebrain neurons after grafts of encapsulated cells secreting human nerve growth factor

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7 January 2021

Nerve growth factor treatment after brain injury prevents neuronal death

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7 January 2021

Methods to assess the development and recovery of locomotor function after spinal cord injury in rats

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7 January 2021

The nerve growth factor 35 years later

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7 January 2021

Repair of adult rat corticospinal tract by transplants of olfactory ensheathing cells.

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7 January 2021

Schwann cells induce sprouting in motor and sensory axons in the adult rat spinal cord

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7 January 2021

Brain-derived neurotrophic factor-transduced fibroblasts: production of BDNF and effects of grafting to the adult rat brain.

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7 January 2021

Age and sex-dependent decreases in ChAT in basal forebrain nuclei

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7 January 2021

Neurotrophin-3: a neurotrophic factor related to NGF and BDNF

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7 January 2021

Transected spinal cords grafted with in situ self-assembled collagen matrices

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7 January 2021

Evaluation of two cross-linked collagen gels implanted in the transected spinal cord.

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7 January 2021

Human nerve growth factor improves spatial memory in aged but not in young rats.

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7 January 2021

Selective effects of nerve growth factor on spatial recent memory as assessed by a delayed nonmatching-to-position task in the water maze.

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7 January 2021

Reversal of age-dependent cognitive impairments and cholinergic neuron atrophy by NGF-secreting neural progenitors grafted to the basal forebrain.

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7 January 2021

Long-term functional recovery from age-induced spatial memory impairments by nerve growth factor gene transfer to the rat basal forebrain

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7 January 2021

CNS-derived neural progenitor cells for gene transfer of nerve growth factor to the adult rat brain: complete rescue of axotomized cholinergic neurons after transplantation into the septum.

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7 January 2021

Cell death of corticospinal neurons is induced by axotomy before but not after innervation of spinal targets.

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7 January 2021

Molecular cloning of rat trkC and distribution of cells expressing messenger RNAs for members of the trk family in the rat central nervous system

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7 January 2021

Nerve growth factor treatment increases brain-derived neurotrophic factor selectively in TrkA-expressing dorsal root ganglion cells and in their central terminations within the spinal cord.

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7 January 2021

Use of retroviral vectors for gene transfer and expression

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7 January 2021

Transfer of genes into human somatic cells using retrovirus vectors

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7 January 2021

Fetal spinal cord transplants rescue some axotomized rubrospinal neurons from retrograde cell death in adult rats.

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7 January 2021

Expression of trk receptors in the developing and adult human central and peripheral nervous system

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7 January 2021

Grafts of fibroblasts genetically modified to secrete NGF, BDNF, NT-3, or basic FGF elicit differential responses in the adult spinal cord

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7 January 2021

Ecdysone-inducible gene expression in mammalian cells and transgenic mice.

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7 January 2021

Nerve growth factor affects 11C-nicotine binding, blood flow, EEG, and verbal episodic memory in an Alzheimer patient (case report).

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7 January 2021

Regrowth of axons in lesioned adult rat spinal cord: promotion by implants of cultured Schwann cells.

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7 January 2021

Correlation of cholinergic abnormalities with senile plaques and mental test scores in senile dementia.

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7 January 2021

New perspectives on Alzheimer's disease

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7 January 2021

Regeneration into the spinal cord of transected dorsal root axons is promoted by ensheathing glia transplants.

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7 January 2021

Expression of biologically active basic fibroblast growth factor by genetically modified rat primary skin fibroblasts.

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7 January 2021

Axons from CNS neurones regenerate into PNS grafts

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7 January 2021

Effects of ibotenic acid lesions of the basal forebrain on serial reversal learning in marmosets.

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7 January 2021

Visuospatial learning impairment following lesion of the cholinergic projection to the hippocampus

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7 January 2021

Grafting genetically modified cells to the damaged brain: restorative effects of NGF expression

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7 January 2021

Intraventricular NGF infusion in the mature rat brain enhances sympathetic innervation of cerebrovascular targets but fails to elicit sympathetic ingrowth

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7 January 2021

Regulation of antioxidant enzyme expression by NGF

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7 January 2021

Neurotrophin-3 enhances sprouting of corticospinal tract during development and after adult spinal cord lesion.

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7 January 2021

Axonal regeneration in the rat spinal cord produced by an antibody against myelin-associated neurite growth inhibitors

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7 January 2021

Sprouting and regeneration of lesioned corticospinal tract fibres in the adult rat spinal cord

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7 January 2021

Myelin-associated inhibitors of neurite growth and regeneration in the CNS.

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7 January 2021

Nerve growth factor (NGF) in the rat CNS: Absence of specific retrograde axonal transport and tyrosine hydroxylase induction in locus coeruleus and substantia nigra

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7 January 2021

Specific retrograde transport of nerve growth factor (NGF) from neocortex to nucleus basalis in the rat.

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7 January 2021

Regional differences in responsiveness of adult CNS axons to grafts of cells expressing human neurotrophin 3.

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7 January 2021

TrkA-immunoreactive profiles in the central nervous system: colocalization with neurons containing p75 nerve growth factor receptor, choline acetyltransferase, and serotonin

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7 January 2021

Fetal grafts alter chronic behavioral outcome after contusion damage to the adult rat spinal cord

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7 January 2021

Rescue of basal forebrain cholinergic neurons after implantation of genetically modified cells producing recombinant NGF.

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7 January 2021

Senile dementia of the Alzheimer type

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7 January 2021

Intraspinal transplants

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7 January 2021

Nerve growth factor delivery by gene transfer induces differential outgrowth of sensory, motor, and noradrenergic neurites after adult spinal cord injury

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7 January 2021

Functional characterization of NGF-secreting cell grafts to the acutely injured spinal cord

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7 January 2021

Fibroblasts genetically modified to produce nerve growth factor induce robust neuritic ingrowth after grafting to the spinal cord

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7 January 2021

Recombinant human nerve growth factor infusions prevent cholinergic neuronal degeneration in the adult primate brain

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7 January 2021

Somatic gene transfer to the adult primate central nervous system: in vitro and in vivo characterization of cells genetically modified to secrete nerve growth factor

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7 January 2021

Nerve growth factor infusion in the primate brain reduces lesion-induced cholinergic neuronal degeneration.

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7 January 2021

Grafts of genetically modified Schwann cells to the spinal cord: survival, axon growth, and myelination

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7 January 2021

Basal forebrain lesions in monkeys disrupt attention but not learning and memory

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7 January 2021

Hypophagia is induced by intracerebroventricular administration of nerve growth factor

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7 January 2021

Reversible Schwann cell hyperplasia and sprouting of sensory and sympathetic neurites after intraventricular administration of nerve growth factor

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7 January 2021

Essential role of neocortical acetylcholine in spatial memory

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7 January 2021

Grafting fibroblasts genetically modified to produce L-dopa in a rat model of Parkinson disease

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7 January 2021

A combination of BDNF and NT-3 promotes supraspinal axonal regeneration into Schwann cell grafts in adult rat thoracic spinal cord.

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7 January 2021

Axonal regeneration into Schwann cell-seeded guidance channels grafted into transected adult rat spinal cord.

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7 January 2021

Mechanisms of neuronal degeneration in Alzheimer's disease

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7 January 2021

Treatment of the chronically injured spinal cord with neurotrophic factors can promote axonal regeneration from supraspinal neurons.

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https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2964033-9

7 January 2021

Response of rubrospinal and corticospinal neurons to injury and neurotrophins

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https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2964033-9

7 January 2021

Pilocarpine and physostigmine attenuate spatial memory impairments produced by lesions of the nucleus basalis magnocellularis

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7 January 2021

10.1016/S0079-6123(08)64033-9

Identifiers

DOI

0 references

PubMed ID

9932426

1 reference

17 December 2017