(Q45858373)

17 December 2017

title

Toward gene therapy for hemophilia A with novel adenoviral vectors: successes and limitations in canine models (English)

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17 December 2017

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Arruda VR

1

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17 December 2017

publication date

1 June 2006

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17 December 2017

Journal of Thrombosis and Haemostasis

published in

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17 December 2017

volume

4

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17 December 2017

issue

6

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17 December 2017

page(s)

1215-1217

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17 December 2017

Gene therapy: twenty-first century medicine

cites work

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2006.01964.X

Improvements in adenoviral vector technology: overcoming barriers for gene therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2006.01964.X

Germline alteration by gene therapy: assessing and reducing the risks

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2006.01964.X

Fatal systemic inflammatory response syndrome in a ornithine transcarbamylase deficient patient following adenoviral gene transfer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2006.01964.X

Expanded-capacity adenoviral vectors--the helper-dependent vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2006.01964.X

A gene-deleted adenoviral vector results in phenotypic correction of canine hemophilia B without liver toxicity or thrombocytopenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2006.01964.X

Administration of helper-dependent adenoviral vectors and sequential delivery of different vector serotype for long-term liver-directed gene transfer in baboons

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2006.01964.X

The Chapel Hill hemophilia A dog colony exhibits a factor VIII gene inversion

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2006.01964.X

Helper-dependent adenoviral gene therapy mediates long-term correction of the clotting defect in the canine hemophilia A model

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2006.01964.X

Therapeutic factor VIII levels and negligible toxicity in mouse and dog models of hemophilia A following gene therapy with high-capacity adenoviral vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2006.01964.X

Helper-dependent adenoviral vectors mediate therapeutic factor VIII expression for several months with minimal accompanying toxicity in a canine model of severe hemophilia A

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2006.01964.X

Gene therapy for hemophilia: an imperative to succeed

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2006.01964.X

Factor VIII alloantibodies in hemophilia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2006.01964.X

Preexisting immunity to adenovirus in rhesus monkeys fails to prevent vector-induced toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2006.01964.X

10.1111/J.1538-7836.2006.01964.X

21 January 2018

Identifiers

DOI

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17 December 2017

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17 December 2017