(Q45861221)

17 December 2017

title

The modest impact of transcription factor Nrf2 on the course of disease in an ALS animal model (English)

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17 December 2017

amyotrophic lateral sclerosis

main subject

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Yansu Guo

1

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17 December 2017

Yuesheng Zhang

2

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17 December 2017

Di Wen

3

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17 December 2017

Weisong Duan

4

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17 December 2017

Ting An

5

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17 December 2017

Pengxiao Shi

6

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17 December 2017

Jingjing Wang

7

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17 December 2017

Zhongyao Li

8

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17 December 2017

Xiaoyu Chen

9

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17 December 2017

Chunyan Li

10

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17 December 2017

publication date

27 May 2013

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17 December 2017

published in

Laboratory Investigation

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17 December 2017

volume

93

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17 December 2017

issue

7

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17 December 2017

page(s)

825-833

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17 December 2017

https://scigraph.springernature.com/pub.10.1038/labinvest.2013.73

exact match

0 references

cites work

Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis

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https://api.crossref.org/works/10.1038%2FLABINVEST.2013.73

Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation

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Nitric oxide-mediated oxidative damage and the progressive demise of motor neurons in ALS.

21 January 2018

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https://api.crossref.org/works/10.1038%2FLABINVEST.2013.73

Oxidative stress in ALS: key role in motor neuron injury and therapeutic target

21 January 2018

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https://api.crossref.org/works/10.1038%2FLABINVEST.2013.73

An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2013.73

Activation of the mouse heme oxygenase-1 gene by 15-deoxy-Delta(12,14)-prostaglandin J(2) is mediated by the stress response elements and transcription factor Nrf2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2013.73

CO/HO-1 Induces NQO-1 Expression via Nrf2 Activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2013.73

An important function of Nrf2 in combating oxidative stress: detoxification of acetaminophen

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2013.73

Nrf2, a Cap'n'Collar transcription factor, regulates induction of the heme oxygenase-1 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2013.73

Neuroprotective effect of Nrf2/ARE activators, CDDO ethylamide and CDDO trifluoroethylamide, in a mouse model of amyotrophic lateral sclerosis

21 January 2018

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Neuroprotective effects of diallyl trisulfide in SOD1-G93A transgenic mouse model of amyotrophic lateral sclerosis.

21 January 2018

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Impaired antioxydative Keap1/Nrf2 system and the downstream stress protein responses in the motor neuron of ALS model mice.

21 January 2018

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Decreased GLT-1 and increased SOD1 and HO-1 expression in astrocytes contribute to lumbar spinal cord vulnerability of SOD1-G93A transgenic mice.

21 January 2018

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Nrf2 activity is lost in the spinal cord and its astrocytes of aged mice

21 January 2018

1 reference

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The Nrf2-ARE pathway: an indicator and modulator of oxidative stress in neurodegeneration

21 January 2018

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Decreased glutathione accelerates neurological deficit and mitochondrial pathology in familial ALS-linked hSOD1(G93A) mice model

21 January 2018

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Glutathione in defense and signaling: lessons from a small thiol

21 January 2018

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Heme oxygenase-1 and neurodegeneration: expanding frontiers of engagement

21 January 2018

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Expression of heme oxygenase-1 in the senescent and Alzheimer-diseased brain

21 January 2018

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Differential upregulation of heme oxygenase-1 (HSP32) in glial cells after oxidative stress and in demyelinating disorders

21 January 2018

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Curcumin upregulates transcription factor Nrf2, HO-1 expression and protects rat brains against focal ischemia.

21 January 2018

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https://api.crossref.org/works/10.1038%2FLABINVEST.2013.73

The role of Nrf2 signaling in the regulation of antioxidants and detoxifying enzymes after traumatic brain injury in rats and mice

21 January 2018

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https://api.crossref.org/works/10.1038%2FLABINVEST.2013.73

Overexpression of CCS in G93A-SOD1 mice leads to accelerated neurological deficits with severe mitochondrial pathology

21 January 2018

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Discovery and development of sulforaphane as a cancer chemopreventive phytochemical

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2013.73

Nrf2-dependent and Nrf2-independent induction of phase 2 detoxifying and antioxidant enzymes during keratinocyte differentiation.

21 January 2018

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https://api.crossref.org/works/10.1038%2FLABINVEST.2013.73

Human haem oxygenase-1 induction by nitro-linoleic acid is mediated by cAMP, AP-1 and E-box response element interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2013.73

Long isoforms of NRF1 contribute to arsenic-induced antioxidant response in human keratinocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2013.73

Nrf2 transcription factor, a novel target of keratinocyte growth factor action which regulates gene expression and inflammation in the healing skin wound

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2013.73

Astrocytes expressing ALS-linked mutated SOD1 release factors selectively toxic to motor neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2013.73

Nrf2 activation in astrocytes protects against neurodegeneration in mouse models of familial amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2013.73

Nuclear factor E2-related factor 2-dependent antioxidant response element activation by tert-butylhydroquinone and sulforaphane occurring preferentially in astrocytes conditions neurons against oxidative insult.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2013.73

Amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2013.73

7 January 2021

Evidence of increased oxidative damage in both sporadic and familial amyotrophic lateral sclerosis.

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2013.73

7 January 2021

Assessing disease onset and progression in the SOD1 mouse model of ALS

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2013.73

7 January 2021

Prevention of glutamate excitotoxicity in motor neurons by 5,6-dihydrocyclopenta-1,2-dithiole-3-thione: implication to the development of neuroprotective drugs

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2013.73

7 January 2021

A role for astrocytes in motor neuron loss in amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2013.73

7 January 2021

Erratum to: Modulation of Nrf2/ARE Pathway by Food Polyphenols: A Nutritional Neuroprotective Strategy for Cognitive and Neurodegenerative Disorders

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2013.73

7 January 2021

Astrocytes interact intimately with degenerating motor neurons in mouse amyotrophic lateral sclerosis (ALS)

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2013.73

7 January 2021

Quinone reductase (NQO1), a sensitive redox indicator, is increased in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2013.73

7 January 2021

Role of oxidative stress in rheumatoid arthritis: insights from the Nrf2-knockout mice

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2013.73

7 January 2021

10.1038/LABINVEST.2013.73

Identifiers

DOI

1 reference

17 December 2017

Dimensions Publication ID

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1 reference

17 December 2017