(Q24623266)

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Neuroprotective effect of Nrf2/ARE activators, CDDO ethylamide and CDDO trifluoroethylamide, in a mouse model of amyotrophic lateral sclerosis

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scholarly article

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Neuroprotective effect of Nrf2/ARE activators, CDDO ethylamide and CDDO trifluoroethylamide, in a mouse model of amyotrophic lateral sclerosis (English)

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amyotrophic lateral sclerosis

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5

object named as

Susanne Petri

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10

object named as

M Flint Beal

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7

object named as

Karen T Liby

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author name string

Arie Neymotin

1

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Noel Y Calingasan

2

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Elizabeth Wille

3

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Nima Naseri

4

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Maria Damiano

6

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Renee Risingsong

8

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Michael Sporn

9

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Mahmoud Kiaei

11

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language of work or name

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publication date

1 July 2011

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Free Radical Biology and Medicine

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51

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1

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88-96

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Vacuolar leukoencephalopathy with widespread astrogliosis in mice lacking transcription factor Nrf2

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20 March 2017

DJ-1, a cancer- and Parkinson's disease-associated protein, stabilizes the antioxidant transcriptional master regulator Nrf2

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20 March 2017

Peroxisome proliferator-activated receptor-gamma coactivator 1 alpha (PGC-1 alpha): transcriptional coactivator and metabolic regulator

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20 March 2017

Isolation of NF-E2-related factor 2 (Nrf2), a NF-E2-like basic leucine zipper transcriptional activator that binds to the tandem NF-E2/AP1 repeat of the beta-globin locus control region

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20 March 2017

Stress-activated cap'n'collar transcription factors in aging and human disease

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20 March 2017

An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements

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20 March 2017

The antioxidant responsive element. Activation by oxidative stress and identification of the DNA consensus sequence required for functional activity

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Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation

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7 April 2017

Metabolic control through the PGC-1 family of transcription coactivators

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7 April 2017

NRF2, a member of the NFE2 family of transcription factors, is not essential for murine erythropoiesis, growth, and development

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7 April 2017

Triterpenoids CDDO-ethyl amide and CDDO-trifluoroethyl amide improve the behavioral phenotype and brain pathology in a transgenic mouse model of Huntington's disease

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27 September 2017

A review of the neural mechanisms of action and clinical efficiency of riluzole in treating amyotrophic lateral sclerosis: what have we learned in the last decade?

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27 September 2017

Astrocyte-specific overexpression of Nrf2 protects striatal neurons from mitochondrial complex II inhibition

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27 September 2017

Mutant SOD1 in neuronal mitochondria causes toxicity and mitochondrial dynamics abnormalities

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27 September 2017

Induction of Nrf2 and xCT are involved in the action of the neuroprotective antibiotic ceftriaxone in vitro.

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27 September 2017

Neuroprotective effects of the triterpenoid, CDDO methyl amide, a potent inducer of Nrf2-mediated transcription.

1 reference

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27 September 2017

Triterpenoid CDDO-methylamide improves memory and decreases amyloid plaques in a transgenic mouse model of Alzheimer's disease

1 reference

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27 September 2017

Nrf2 activation in astrocytes protects against neurodegeneration in mouse models of familial amyotrophic lateral sclerosis

1 reference

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27 September 2017

Keap1/Nrf2 signaling regulates oxidative stress tolerance and lifespan in Drosophila

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27 September 2017

Molecular biology of amyotrophic lateral sclerosis: insights from genetics

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Translating preclinical insights into effective human trials in ALS.

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27 September 2017

The Nrf2-ARE Signalling pathway: promising drug target to combat oxidative stress in neurodegenerative disorders

1 reference

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27 September 2017

Protection from mitochondrial complex II inhibition in vitro and in vivo by Nrf2-mediated transcription

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27 September 2017

Mitochondrial degeneration in amyotrophic lateral sclerosis.

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27 September 2017

Complexity of CNC transcription factors as revealed by gene targeting of the Nrf3 locus

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27 September 2017

Transcriptional regulatory circuits controlling mitochondrial biogenesis and function

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27 September 2017

Relevance of oxidative injury in the pathogenesis of motor neuron diseases

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27 September 2017

Programmed cell death in amyotrophic lateral sclerosis: a mechanism of pathogenic and therapeutic importance

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27 September 2017

Protein aggregation in motor neurone disorders.

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27 September 2017

Antioxidants Enhance Mammalian Proteasome Expression through the Keap1-Nrf2 Signaling Pathway

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27 September 2017

Functions of intermediate filaments in neuronal development and disease

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27 September 2017

NF-E2-related factor-2 mediates neuroprotection against mitochondrial complex I inhibitors and increased concentrations of intracellular calcium in primary cortical neurons

1 reference

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27 September 2017

Coordinate Regulation of Glutathione Biosynthesis and Release by Nrf2-Expressing Glia Potently Protects Neurons from Oxidative Stress

1 reference

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27 September 2017

Glutamate transporters in neurologic disease

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27 September 2017

Excitotoxic mechanisms in the pathogenesis of amyotrophic lateral sclerosis.

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27 September 2017

Rat liver aldehyde reductase

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27 September 2017

Focal dysfunction of the proteasome: a pathogenic factor in a mouse model of amyotrophic lateral sclerosis

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30 May 2018

Message and protein-level elevation of tumor necrosis factor alpha (TNF alpha) and TNF alpha-modulating cytokines in spinal cords of the G93A-SOD1 mouse model for amyotrophic lateral sclerosis

1 reference

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30 May 2018

Involvement of the retinoblastoma protein in brown and white adipocyte cell differentiation: functional and physical association with the adipogenic transcription factor C/EBPalpha

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30 May 2018

Neuroblastoma x spinal cord (NSC) hybrid cell lines resemble developing motor neurons

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30 May 2018

Cytoplasmic aldo-keto reductases: a class of drug metabolizing enzymes

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30 May 2018

Nuclear erythroid 2-related factor 2-antioxidative response element signaling pathway in motor cortex and spinal cord in amyotrophic lateral sclerosis

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28 November 2018

Increased glutathione biosynthesis by Nrf2 activation in astrocytes prevents p75NTR-dependent motor neuron apoptosis

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28 November 2018

Thalidomide and lenalidomide extend survival in a transgenic mouse model of amyotrophic lateral sclerosis.

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28 November 2018

Integrative role of cPLA with COX-2 and the effect of non-steriodal anti-inflammatory drugs in a transgenic mouse model of amyotrophic lateral sclerosis

1 reference

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28 November 2018

Rat embryonic motoneurons in long-term co-culture with Schwann cells--a system to investigate motoneuron diseases on a cellular level in vitro.

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28 November 2018

CHIP promotes proteasomal degradation of familial ALS-linked mutant SOD1 by ubiquitinating Hsp/Hsc70.

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28 November 2018

Additive neuroprotective effects of creatine and cyclooxygenase 2 inhibitors in a transgenic mouse model of amyotrophic lateral sclerosis

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28 November 2018

Cyclooxygenase 2 inhibition protects motor neurons and prolongs survival in a transgenic mouse model of ALS.

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28 November 2018

Proteasomal inhibition by misfolded mutant superoxide dismutase 1 induces selective motor neuron death in familial amyotrophic lateral sclerosis

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28 November 2018

Motoneuron death triggered by a specific pathway downstream of Fas. potentiation by ALS-linked SOD1 mutations.

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28 November 2018

Increased levels of the pro-inflammatory prostaglandin PGE2 in CSF from ALS patients

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28 November 2018

A novel dicyanotriterpenoid, 2-cyano-3,12-dioxooleana-1,9(11)-dien-28-onitrile, active at picomolar concentrations for inhibition of nitric oxide production

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28 November 2018

Increased expression of the pro-inflammatory enzyme cyclooxygenase-2 in amyotrophic lateral sclerosis.

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28 November 2018

Loss of Fas ligand-function improves survival in G93A-transgenic ALS mice

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Matrix metalloproteinase-9 regulates TNF-alpha and FasL expression in neuronal, glial cells and its absence extends life in a transgenic mouse model of amyotrophic lateral sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/21457778

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

1 reference

https://api.crossref.org/works/10.1016%2FJ.FREERADBIOMED.2011.03.027

7 January 2021

based on heuristic

inferred from DOI database lookup

Detection of specific polymerase chain reaction product by utilizing the 5'----3' exonuclease activity of Thermus aquaticus DNA polymerase

1 reference

https://api.crossref.org/works/10.1016%2FJ.FREERADBIOMED.2011.03.027

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1016/J.FREERADBIOMED.2011.03.027

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PMC publication ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PubMed publication ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

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