(Q52114306)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12354397%20AND%20SRC:MED&resulttype=core&format=json

13 December 2019

title

Motoneuron death triggered by a specific pathway downstream of Fas. potentiation by ALS-linked SOD1 mutations (English)

1 reference

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amyotrophic lateral sclerosis

13 December 2019

main subject

1 reference

1

1 reference

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13 December 2019

Don W. Cleveland

4

1 reference

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13 December 2019

Christopher E. Henderson

6

1 reference

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13 December 2019

8

Brigitte Pettmann

1 reference

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13 December 2019

author name string

Alvaro G Estévez

2

1 reference

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13 December 2019

Hiroshi Nishimune

3

1 reference

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13 December 2019

Odile deLapeyrière

5

1 reference

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13 December 2019

Georg Haase

7

1 reference

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13 December 2019

language of work or name

English

0 references

publication date

1 September 2002

1 reference

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13 December 2019

1 reference

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13 December 2019

volume

35

1 reference

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13 December 2019

issue

6

1 reference

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13 December 2019

page(s)

1067-1083

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Targeted mutation in the Fas gene causes hyperplasia in peripheral lymphoid organs and liver

13 December 2019

cites work

1 reference

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7 January 2021

Inducible nitric oxide synthase up-regulation in a transgenic mouse model of familial amyotrophic lateral sclerosis

1 reference

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7 January 2021

Glial cells of the spinal cord and subcortical white matter up-regulate neuronal nitric oxide synthase in sporadic amyotrophic lateral sclerosis

1 reference

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7 January 2021

Cardiotrophin-1 requires LIFRbeta to promote survival of mouse motoneurons purified by a novel technique

1 reference

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7 January 2021

Design of isoform-selective inhibitors of nitric oxide synthase

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7 January 2021

TNFalpha contributes to the death of NGF-dependent neurons during development

1 reference

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7 January 2021

Extensive nitration of protein tyrosines in human atherosclerosis detected by immunohistochemistry

1 reference

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7 January 2021

Superoxide dismutase and the death of motoneurons in ALS.

1 reference

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7 January 2021

Cell-permeable peptide inhibitors of JNK: novel blockers of beta-cell death

1 reference

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7 January 2021

CEP-1347/KT7515, a JNK pathway inhibitor, supports the in vitro survival of chick embryonic neurons.

1 reference

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7 January 2021

Superoxide dismutase 1 with mutations linked to familial amyotrophic lateral sclerosis possesses significant activity

1 reference

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7 January 2021

ALS-linked SOD1 mutant G85R mediates damage to astrocytes and promotes rapidly progressive disease with SOD1-containing inclusions.

1 reference

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7 January 2021

Increased expression of neuronal nitric oxide synthase spliced variants in reactive astrocytes of amyotrophic lateral sclerosis human spinal cord

1 reference

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7 January 2021

Activation of apoptosis signal-regulating kinase 1 (ASK1) by the adapter protein Daxx

1 reference

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7 January 2021

Mechanisms underlying neuronal death induced by chromogranin A-activated microglia

1 reference

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7 January 2021

Cu,Zn-superoxide dismutase-dependent apoptosis induced by nitric oxide in neuronal cells

1 reference

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7 January 2021

Death of motoneurons induced by trophic deprivation or by excitotoxicity is not prevented by overexpression of SMN.

1 reference

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7 January 2021

From Charcot to Lou Gehrig: deciphering selective motor neuron death in ALS

1 reference

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7 January 2021

Blockade of p38 mitogen-activated protein kinase pathway inhibits inducible nitric-oxide synthase expression in mouse astrocytes

1 reference

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7 January 2021

BAX is required for neuronal death after trophic factor deprivation and during development

1 reference

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7 January 2021

Aggregation of mutant Cu/Zn superoxide dismutase proteins in a culture model of ALS

1 reference

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7 January 2021

Role of endogenous nitric oxide and peroxynitrite formation in the survival and death of motor neurons in culture.

1 reference

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7 January 2021

Nitric oxide and superoxide contribute to motor neuron apoptosis induced by trophic factor deprivation.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900905-4

7 January 2021

Induction of nitric oxide-dependent apoptosis in motor neurons by zinc-deficient superoxide dismutase

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900905-4

7 January 2021

Lack of involvement of neuronal nitric oxide synthase in the pathogenesis of a transgenic mouse model of familial amyotrophic lateral sclerosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900905-4

7 January 2021

Synergy between T cell Receptor and Fas (CD95/APO-1) signaling in mouse thymocyte death

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900905-4

7 January 2021

Microglia-Derived Nerve Growth Factor Causes Cell Death in the Developing Retina

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900905-4

7 January 2021

Early and selective loss of neuromuscular synapse subtypes with low sprouting competence in motoneuron diseases

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900905-4

7 January 2021

Mutant superoxide dismutase-1-linked familial amyotrophic lateral sclerosis: molecular mechanisms of neuronal death and protection

1 reference

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7 January 2021

Restricted expression of G86R Cu/Zn superoxide dismutase in astrocytes results in astrocytosis but does not cause motoneuron degeneration

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900905-4

7 January 2021

The central executioners of apoptosis: caspases or mitochondria?

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900905-4

7 January 2021

Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900905-4

7 January 2021

The antinociceptive effect of 1-(2-trifluoromethylphenyl) imidazole (TRIM), a potent inhibitor of neuronal nitric oxide synthase in vitro, in the mouse

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900905-4

7 January 2021

Signalling for survival and death in neurones: the role of stress-activated kinases, JNK and p38

1 reference

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7 January 2021

Lasting N-terminal phosphorylation of c-Jun and activation of c-Jun N-terminal kinases after neuronal injury.

1 reference

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7 January 2021

Amyotrophic lateral sclerosis. unfolding the toxicity of the misfolded

1 reference

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7 January 2021

Role of apoptosis signal-regulating kinase in regulation of the c-Jun N-terminal kinase pathway and apoptosis in sympathetic neurons

1 reference

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7 January 2021

Neuromuscular function impairment is not caused by motor neurone loss in FALS mice: an electromyographic study

1 reference

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7 January 2021

Bax-deficient mice with lymphoid hyperplasia and male germ cell death

1 reference

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7 January 2021

Bcl-2: prolonging life in a transgenic mouse model of familial amyotrophic lateral sclerosis

1 reference

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7 January 2021

CD95's deadly mission in the immune system

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900905-4

7 January 2021

Withdrawal of survival factors results in activation of the JNK pathway in neuronal cells leading to Fas ligand induction and cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900905-4

7 January 2021

Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900905-4

7 January 2021

Functional Role of Caspase-1 and Caspase-3 in an ALS Transgenic Mouse Model

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900905-4

7 January 2021

Accumulation of SOD1 mutants in postnatal motoneurons does not cause motoneuron pathology or motoneuron disease

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900905-4

7 January 2021

A potential role for the p75 low-affinity neurotrophin receptor in spinal motor neuron degeneration in murine and human amyotrophic lateral sclerosis

1 reference

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7 January 2021

Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900905-4

7 January 2021

Motoneuron apoptosis is blocked by CEP-1347 (KT 7515), a novel inhibitor of the JNK signaling pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900905-4

7 January 2021

Fas receptor and neuronal cell death after spinal cord ischemia

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900905-4

7 January 2021

Localization of Fas antigen mRNA induced in postischemic murine forebrain by in situ hybridization

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900905-4

7 January 2021

Loss of Daxx, a promiscuously interacting protein, results in extensive apoptosis in early mouse development

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900905-4

7 January 2021

JNK and p38 stresskinases--degenerative effectors of signal-transduction-cascades in the nervous system

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900905-4

7 January 2021

A study of apoptosis in normal and pathologic nervous tissue after in situ end-labeling of DNA strand breaks

1 reference

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7 January 2021

Lack of apoptosis in mice with ALS

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900905-4

7 January 2021

Beta-amyloid induces neuronal apoptosis via a mechanism that involves the c-Jun N-terminal kinase pathway and the induction of Fas ligand.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900905-4

7 January 2021

Apoptosis by death factor

1 reference

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7 January 2021

Delayed neurodegeneration in neonatal rat thalamus after hypoxia-ischemia is apoptosis.

1 reference

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7 January 2021

Selective apoptosis of CD4+CD8+ thymocytes by the anti-Fas antibody

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900905-4

7 January 2021

The p38 signal transduction pathway: activation and function

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900905-4

7 January 2021

Caspase-1 and -3 are sequentially activated in motor neuron death in Cu,Zn superoxide dismutase-mediated familial amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900905-4

7 January 2021

Stress-activated protein kinases: activation, regulation and function.

1 reference

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7 January 2021

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900905-4

1 reference

7 January 2021

Biologically active basic fibroblast growth factor migrates at 27 kD in "non-denaturing" SDS-polyacrylamide gel electrophoresis

1 reference

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7 January 2021

Neuron-specific expression of mutant superoxide dismutase 1 in transgenic mice does not lead to motor impairment.

1 reference

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7 January 2021

Mutations associated with amyotrophic lateral sclerosis convert superoxide dismutase from an antiapoptotic gene to a proapoptotic gene: studies in yeast and neural cells

1 reference

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7 January 2021

Programmed cell death of embryonic motoneurons triggered through the Fas death receptor

1 reference

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7 January 2021

Active killing of neurons during development and following stress: a role for p75(NTR) and Fas?

1 reference

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7 January 2021

Superoxide reacts with nitric oxide to nitrate tyrosine at physiological pH via peroxynitrite.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900905-4

7 January 2021

Apoptotic death of neurons exhibiting peripherin aggregates is mediated by the proinflammatory cytokine tumor necrosis factor-alpha

1 reference

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7 January 2021

Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900905-4

7 January 2021

Dynamic regulation of neuronal NO synthase transcription by calcium influx through a CREB family transcription factor-dependent mechanism

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900905-4

7 January 2021

Two CD95 (APO-1/Fas) signaling pathways

1 reference

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7 January 2021

Differential modulation of apoptosis sensitivity in CD95 type I and type II cells.

1 reference

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7 January 2021

Bcl-xL functions downstream of caspase-8 to inhibit Fas- and tumor necrosis factor receptor 1-induced apoptosis of MCF7 breast carcinoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900905-4

7 January 2021

In situ immunodetection of activated caspase-3 in apoptotic neurons in the developing nervous system

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900905-4

7 January 2021

Soluble TNF receptors partially protect injured motoneurons in the postnatal CNS

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900905-4

7 January 2021

ASK1 is required for sustained activations of JNK/p38 MAP kinases and apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900905-4

7 January 2021

Administration of nitric oxide synthase inhibitors does not alter disease course of amyotrophic lateral sclerosis SOD1 mutant transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900905-4

7 January 2021

Trophic activities for dorsal root and sympathetic ganglionic neurons in media conditioned by Schwann and other peripheral cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900905-4

7 January 2021

An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900905-4

7 January 2021

Daxx, a novel Fas-binding protein that activates JNK and apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900905-4

7 January 2021

In vitro induction of neuronal apoptosis by anti-Fas antibody-containing sera from amyotrophic lateral sclerosis patients.

1 reference

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7 January 2021

Potent and selective inhibition of neuronal nitric oxide synthase by N omega-propyl-L-arginine

1 reference

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7 January 2021

10.1016/S0896-6273(02)00905-4

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12354397%20AND%20SRC:MED&resulttype=core&format=json

13 December 2019

1 reference